A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells

Autores
Boztepe, Tugce; Sólimo, Aldana; Goldberg, Tatiana; Santa María de la Parra, Lucía; Islan, Germán Abel; Callero, Mariana; León, Ignacio Esteban
Año de publicación
2024
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Platinum-based drugs are commonly used due to their effectiveness and ability to target various types of cancers. However, over time, cancer cells can develop drug resistance, making the treatment less effective. Additionally, these drugs can have high toxicity and cause harmful side effects in patients. On the other hand, copper-based complexes have attracted attention as potential alternatives. Early in vitro and in vivo studies have shown that they may have promising antitumor activities, offering a potentially effective and less toxic option for cancer treatment. Drug delivery systems offer significant benefits in cancer treatment by enhancing the delivery of therapeutics, reducing side effects, and improving drug efficacy and bioavailability at tumor sites. Eudragit polymers are widely used in drug delivery systems due to their versatility in controlling the release profile of drugs, offering protection to active compounds, and enhancing targeted delivery to specific areas of the body.
Centro de Química Inorgánica
Materia
Ciencias Exactas
Química
copper-based complexes
antitumor activities
drug delivery systems
cancer treatment
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/192238
Acceder
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network_name_str SEDICI (UNLP)
spelling A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cellsBoztepe, TugceSólimo, AldanaGoldberg, TatianaSanta María de la Parra, LucíaIslan, Germán AbelCallero, MarianaLeón, Ignacio EstebanCiencias ExactasQuímicacopper-based complexesantitumor activitiesdrug delivery systemscancer treatmentPlatinum-based drugs are commonly used due to their effectiveness and ability to target various types of cancers. However, over time, cancer cells can develop drug resistance, making the treatment less effective. Additionally, these drugs can have high toxicity and cause harmful side effects in patients. On the other hand, copper-based complexes have attracted attention as potential alternatives. Early in vitro and in vivo studies have shown that they may have promising antitumor activities, offering a potentially effective and less toxic option for cancer treatment. Drug delivery systems offer significant benefits in cancer treatment by enhancing the delivery of therapeutics, reducing side effects, and improving drug efficacy and bioavailability at tumor sites. Eudragit polymers are widely used in drug delivery systems due to their versatility in controlling the release profile of drugs, offering protection to active compounds, and enhancing targeted delivery to specific areas of the body.Centro de Química Inorgánica2024-10info:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/publishedVersionResumenhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/192238enginfo:eu-repo/semantics/altIdentifier/url/https://congresos.unlp.edu.ar/jqi/wp-content/uploads/sites/55/2024/10/Boztepe_T.pdfinfo:eu-repo/semantics/altIdentifier/url/https://congresos.unlp.edu.ar/jqi/wp-content/uploads/sites/55/2024/09/28_Boztepe_T.pdfinfo:eu-repo/semantics/altIdentifier/issn/2953-4267info:eu-repo/semantics/reference/url/https://sedici.unlp.edu.ar/handle/10915/183483info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2026-05-06T13:00:22Zoai:sedici.unlp.edu.ar:10915/192238Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292026-05-06 13:00:22.578SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
title A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
spellingShingle A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
Boztepe, Tugce
Ciencias Exactas
Química
copper-based complexes
antitumor activities
drug delivery systems
cancer treatment
title_short A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
title_full A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
title_fullStr A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
title_full_unstemmed A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
title_sort A new copper(II) complex-loaded Eudragit® nanoparticles against triple-negative breast cancer cells
dc.creator.none.fl_str_mv Boztepe, Tugce
Sólimo, Aldana
Goldberg, Tatiana
Santa María de la Parra, Lucía
Islan, Germán Abel
Callero, Mariana
León, Ignacio Esteban
author Boztepe, Tugce
author_facet Boztepe, Tugce
Sólimo, Aldana
Goldberg, Tatiana
Santa María de la Parra, Lucía
Islan, Germán Abel
Callero, Mariana
León, Ignacio Esteban
author_role author
author2 Sólimo, Aldana
Goldberg, Tatiana
Santa María de la Parra, Lucía
Islan, Germán Abel
Callero, Mariana
León, Ignacio Esteban
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Química
copper-based complexes
antitumor activities
drug delivery systems
cancer treatment
topic Ciencias Exactas
Química
copper-based complexes
antitumor activities
drug delivery systems
cancer treatment
dc.description.none.fl_txt_mv Platinum-based drugs are commonly used due to their effectiveness and ability to target various types of cancers. However, over time, cancer cells can develop drug resistance, making the treatment less effective. Additionally, these drugs can have high toxicity and cause harmful side effects in patients. On the other hand, copper-based complexes have attracted attention as potential alternatives. Early in vitro and in vivo studies have shown that they may have promising antitumor activities, offering a potentially effective and less toxic option for cancer treatment. Drug delivery systems offer significant benefits in cancer treatment by enhancing the delivery of therapeutics, reducing side effects, and improving drug efficacy and bioavailability at tumor sites. Eudragit polymers are widely used in drug delivery systems due to their versatility in controlling the release profile of drugs, offering protection to active compounds, and enhancing targeted delivery to specific areas of the body.
Centro de Química Inorgánica
description Platinum-based drugs are commonly used due to their effectiveness and ability to target various types of cancers. However, over time, cancer cells can develop drug resistance, making the treatment less effective. Additionally, these drugs can have high toxicity and cause harmful side effects in patients. On the other hand, copper-based complexes have attracted attention as potential alternatives. Early in vitro and in vivo studies have shown that they may have promising antitumor activities, offering a potentially effective and less toxic option for cancer treatment. Drug delivery systems offer significant benefits in cancer treatment by enhancing the delivery of therapeutics, reducing side effects, and improving drug efficacy and bioavailability at tumor sites. Eudragit polymers are widely used in drug delivery systems due to their versatility in controlling the release profile of drugs, offering protection to active compounds, and enhancing targeted delivery to specific areas of the body.
publishDate 2024
dc.date.none.fl_str_mv 2024-10
dc.type.none.fl_str_mv info:eu-repo/semantics/conferenceObject
info:eu-repo/semantics/publishedVersion
Resumen
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
format conferenceObject
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/192238
url http://sedici.unlp.edu.ar/handle/10915/192238
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://congresos.unlp.edu.ar/jqi/wp-content/uploads/sites/55/2024/10/Boztepe_T.pdf
info:eu-repo/semantics/altIdentifier/url/https://congresos.unlp.edu.ar/jqi/wp-content/uploads/sites/55/2024/09/28_Boztepe_T.pdf
info:eu-repo/semantics/altIdentifier/issn/2953-4267
info:eu-repo/semantics/reference/url/https://sedici.unlp.edu.ar/handle/10915/183483
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.1485815

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