Relationship between Systolic Arterial Pressure and Heart Mass in the Rat

Autores
Grassi de Gende, Ángela
Año de publicación
1993
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study describes the relationship between left ventricular mass and systolic arterial pressure (SAP) in normotensive and hypertensive rats. The genetically hypertensive rats (SHR) were stratified according to their SAP values in to hypertensive (SHRH) and normotensive (SHRN) subgroups. Males and females of both subgroups exhibited biventricular hypertrophy and the left ventricular mass was not correlated with SAP values. An overall cardiac enlargement was also found in female rats of the normotensive WKY group. In DOCA-salt and 2K/1C hypertensive rats the left ventricular mass was correlated positively with SAP. These data suggest that SAP is not a factor in the development of left ventricular hypertrophy in the SHR strain, however, they also revealed a right ventricular mass increase in this strain with respect to the Wistar strain.
Facultad de Ciencias Médicas
Materia
Ciencias Médicas
Hypertension
Left and right ventricular mass
SHR strain
WKY strain
Mineralocorticoid hypertension
Renal hypertension
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/132838
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/132838
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Relationship between Systolic Arterial Pressure and Heart Mass in the RatGrassi de Gende, ÁngelaCiencias MédicasHypertensionLeft and right ventricular massSHR strainWKY strainMineralocorticoid hypertensionRenal hypertensionThis study describes the relationship between left ventricular mass and systolic arterial pressure (SAP) in normotensive and hypertensive rats. The genetically hypertensive rats (SHR) were stratified according to their SAP values in to hypertensive (SHRH) and normotensive (SHRN) subgroups. Males and females of both subgroups exhibited biventricular hypertrophy and the left ventricular mass was not correlated with SAP values. An overall cardiac enlargement was also found in female rats of the normotensive WKY group. In DOCA-salt and 2K/1C hypertensive rats the left ventricular mass was correlated positively with SAP. These data suggest that SAP is not a factor in the development of left ventricular hypertrophy in the SHR strain, however, they also revealed a right ventricular mass increase in this strain with respect to the Wistar strain.Facultad de Ciencias Médicas1993info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf795-801http://sedici.unlp.edu.ar/handle/10915/132838enginfo:eu-repo/semantics/altIdentifier/issn/0021-4868info:eu-repo/semantics/altIdentifier/issn/1348-673Xinfo:eu-repo/semantics/altIdentifier/doi/10.1536/ihj.34.795info:eu-repo/semantics/altIdentifier/pmid/8164346info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:03:49Zoai:sedici.unlp.edu.ar:10915/132838Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:03:49.342SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
title Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
spellingShingle Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
Grassi de Gende, Ángela
Ciencias Médicas
Hypertension
Left and right ventricular mass
SHR strain
WKY strain
Mineralocorticoid hypertension
Renal hypertension
title_short Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
title_full Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
title_fullStr Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
title_full_unstemmed Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
title_sort Relationship between Systolic Arterial Pressure and Heart Mass in the Rat
dc.creator.none.fl_str_mv Grassi de Gende, Ángela
author Grassi de Gende, Ángela
author_facet Grassi de Gende, Ángela
author_role author
dc.subject.none.fl_str_mv Ciencias Médicas
Hypertension
Left and right ventricular mass
SHR strain
WKY strain
Mineralocorticoid hypertension
Renal hypertension
topic Ciencias Médicas
Hypertension
Left and right ventricular mass
SHR strain
WKY strain
Mineralocorticoid hypertension
Renal hypertension
dc.description.none.fl_txt_mv This study describes the relationship between left ventricular mass and systolic arterial pressure (SAP) in normotensive and hypertensive rats. The genetically hypertensive rats (SHR) were stratified according to their SAP values in to hypertensive (SHRH) and normotensive (SHRN) subgroups. Males and females of both subgroups exhibited biventricular hypertrophy and the left ventricular mass was not correlated with SAP values. An overall cardiac enlargement was also found in female rats of the normotensive WKY group. In DOCA-salt and 2K/1C hypertensive rats the left ventricular mass was correlated positively with SAP. These data suggest that SAP is not a factor in the development of left ventricular hypertrophy in the SHR strain, however, they also revealed a right ventricular mass increase in this strain with respect to the Wistar strain.
Facultad de Ciencias Médicas
description This study describes the relationship between left ventricular mass and systolic arterial pressure (SAP) in normotensive and hypertensive rats. The genetically hypertensive rats (SHR) were stratified according to their SAP values in to hypertensive (SHRH) and normotensive (SHRN) subgroups. Males and females of both subgroups exhibited biventricular hypertrophy and the left ventricular mass was not correlated with SAP values. An overall cardiac enlargement was also found in female rats of the normotensive WKY group. In DOCA-salt and 2K/1C hypertensive rats the left ventricular mass was correlated positively with SAP. These data suggest that SAP is not a factor in the development of left ventricular hypertrophy in the SHR strain, however, they also revealed a right ventricular mass increase in this strain with respect to the Wistar strain.
publishDate 1993
dc.date.none.fl_str_mv 1993
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/132838
url http://sedici.unlp.edu.ar/handle/10915/132838
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0021-4868
info:eu-repo/semantics/altIdentifier/issn/1348-673X
info:eu-repo/semantics/altIdentifier/doi/10.1536/ihj.34.795
info:eu-repo/semantics/altIdentifier/pmid/8164346
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.format.none.fl_str_mv application/pdf
795-801
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.13397

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