Emulsan, a tailorable biopolymer for controlled release

Autores
Castro, Guillermo Raúl; Panilaitis, Bruce; Kaplan, David L.
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Microsphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating agent. BSA adsorption by emulsan–alginate microspheres is also enhanced 40% compared to alginate alone. XPS studies confirm the presence of BSA adsorbed on emulsan microsphere surfaces. These results are in agreement with the equilibrium adsorption model of Freundlich. Studies of BSA adsorption using non-equilibrium Lagergren second-order and intraparticle models, are suggesting a complex mechanisms of protein adsorption by chemisorption and intraparticle diffusion. Also, enzymatic release of BSA from emulsan microspheres containing azo-BSA under physiological conditions is suggests the possibility of using microspheres as a depot for pre-proteins of medical interest.
Centro de Investigación y Desarrollo en Fermentaciones Industriales
Materia
Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/152994
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/152994
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Emulsan, a tailorable biopolymer for controlled releaseCastro, Guillermo RaúlPanilaitis, BruceKaplan, David L.BioquímicaEmulsanBioemulsifierControlled releaseAgricultureFermentationMicrosphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating agent. BSA adsorption by emulsan–alginate microspheres is also enhanced 40% compared to alginate alone. XPS studies confirm the presence of BSA adsorbed on emulsan microsphere surfaces. These results are in agreement with the equilibrium adsorption model of Freundlich. Studies of BSA adsorption using non-equilibrium Lagergren second-order and intraparticle models, are suggesting a complex mechanisms of protein adsorption by chemisorption and intraparticle diffusion. Also, enzymatic release of BSA from emulsan microspheres containing azo-BSA under physiological conditions is suggests the possibility of using microspheres as a depot for pre-proteins of medical interest.Centro de Investigación y Desarrollo en Fermentaciones Industriales2008info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/152994enginfo:eu-repo/semantics/altIdentifier/issn/0960-8524info:eu-repo/semantics/altIdentifier/issn/1873-2976info:eu-repo/semantics/altIdentifier/doi/10.1016/j.biortech.2007.06.059info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:11:34Zoai:sedici.unlp.edu.ar:10915/152994Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:11:35.094SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Emulsan, a tailorable biopolymer for controlled release
title Emulsan, a tailorable biopolymer for controlled release
spellingShingle Emulsan, a tailorable biopolymer for controlled release
Castro, Guillermo Raúl
Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
title_short Emulsan, a tailorable biopolymer for controlled release
title_full Emulsan, a tailorable biopolymer for controlled release
title_fullStr Emulsan, a tailorable biopolymer for controlled release
title_full_unstemmed Emulsan, a tailorable biopolymer for controlled release
title_sort Emulsan, a tailorable biopolymer for controlled release
dc.creator.none.fl_str_mv Castro, Guillermo Raúl
Panilaitis, Bruce
Kaplan, David L.
author Castro, Guillermo Raúl
author_facet Castro, Guillermo Raúl
Panilaitis, Bruce
Kaplan, David L.
author_role author
author2 Panilaitis, Bruce
Kaplan, David L.
author2_role author
author
dc.subject.none.fl_str_mv Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
topic Bioquímica
Emulsan
Bioemulsifier
Controlled release
Agriculture
Fermentation
dc.description.none.fl_txt_mv Microsphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating agent. BSA adsorption by emulsan–alginate microspheres is also enhanced 40% compared to alginate alone. XPS studies confirm the presence of BSA adsorbed on emulsan microsphere surfaces. These results are in agreement with the equilibrium adsorption model of Freundlich. Studies of BSA adsorption using non-equilibrium Lagergren second-order and intraparticle models, are suggesting a complex mechanisms of protein adsorption by chemisorption and intraparticle diffusion. Also, enzymatic release of BSA from emulsan microspheres containing azo-BSA under physiological conditions is suggests the possibility of using microspheres as a depot for pre-proteins of medical interest.
Centro de Investigación y Desarrollo en Fermentaciones Industriales
description Microsphere hydrogels made with emulsan–alginate were used as carrier for the microencapsulation of blue dextran in order to study the effect of emulsan on the alginate bead stability. Blue dextran release studies indicated an increase of microsphere stability in presence of emulsan, as a coating agent. BSA adsorption by emulsan–alginate microspheres is also enhanced 40% compared to alginate alone. XPS studies confirm the presence of BSA adsorbed on emulsan microsphere surfaces. These results are in agreement with the equilibrium adsorption model of Freundlich. Studies of BSA adsorption using non-equilibrium Lagergren second-order and intraparticle models, are suggesting a complex mechanisms of protein adsorption by chemisorption and intraparticle diffusion. Also, enzymatic release of BSA from emulsan microspheres containing azo-BSA under physiological conditions is suggests the possibility of using microspheres as a depot for pre-proteins of medical interest.
publishDate 2008
dc.date.none.fl_str_mv 2008
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/152994
url http://sedici.unlp.edu.ar/handle/10915/152994
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0960-8524
info:eu-repo/semantics/altIdentifier/issn/1873-2976
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.biortech.2007.06.059
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.13397

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