Extended phylogeny of the equine arteritis virus sequences including South American sequences

Autores
Metz, Germán Ernesto; Martín Ocampos, Giselle Paula; Serena, María Soledad; Gambaro, Sabrina Eliana; Nosetto, Edgardo Omar; Echeverría, María Gabriela
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objective: To perform genetic analysis of the ORF5 of equine arteritis virus (EAV) may provide new insights into the genetic evolution and origin of the Argentinean EAV sequences. Methods: A total of 76 sequences were analyzed by neighbor joining (NJ), maximum parsimony and maximum likelihood algorithms. The analysis of the selective pressures was performed using the Tajima's test. Results: The trees showed similar topologies. Two clades were identified: the first clade was formed by strains isolated mainly from a donkey, whereas the second clade presented four large groups from different geographic regions exclusively from Equus caballus. In this clade, we identified a group formed by South African and another one by South American and European sequences. In the latter, the monophyletic group was formed by seven Argentinean sequences. In the NJ tree, we identified a group formed by six Argentinean sequences. The Tajima's test showed a D value of 1.73663, indicating that the sequences analyzed follow a neutral evolution model. Conclusion: We concluded that the Argentinean sequences have a paraphyletic origin and that the fixation of point mutation might follow the neutral model evolution; however, we identified purifying pressures that may be involved in the differentiation of the EAV sequences.
Facultad de Ciencias Veterinarias
Materia
Ciencias Veterinarias
Equine arteritis virus
Equine arteritis, Argentina
Phylogenetic analysis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/82438
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/82438
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Extended phylogeny of the equine arteritis virus sequences including South American sequencesMetz, Germán ErnestoMartín Ocampos, Giselle PaulaSerena, María SoledadGambaro, Sabrina ElianaNosetto, Edgardo OmarEcheverría, María GabrielaCiencias VeterinariasEquine arteritis virusEquine arteritis, ArgentinaPhylogenetic analysisObjective: To perform genetic analysis of the ORF5 of equine arteritis virus (EAV) may provide new insights into the genetic evolution and origin of the Argentinean EAV sequences. Methods: A total of 76 sequences were analyzed by neighbor joining (NJ), maximum parsimony and maximum likelihood algorithms. The analysis of the selective pressures was performed using the Tajima's test. Results: The trees showed similar topologies. Two clades were identified: the first clade was formed by strains isolated mainly from a donkey, whereas the second clade presented four large groups from different geographic regions exclusively from Equus caballus. In this clade, we identified a group formed by South African and another one by South American and European sequences. In the latter, the monophyletic group was formed by seven Argentinean sequences. In the NJ tree, we identified a group formed by six Argentinean sequences. The Tajima's test showed a D value of 1.73663, indicating that the sequences analyzed follow a neutral evolution model. Conclusion: We concluded that the Argentinean sequences have a paraphyletic origin and that the fixation of point mutation might follow the neutral model evolution; however, we identified purifying pressures that may be involved in the differentiation of the EAV sequences.Facultad de Ciencias Veterinarias2010info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf30-36http://sedici.unlp.edu.ar/handle/10915/82438enginfo:eu-repo/semantics/altIdentifier/issn/0300-5526info:eu-repo/semantics/altIdentifier/doi/10.1159/000318925info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T10:47:46Zoai:sedici.unlp.edu.ar:10915/82438Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 10:47:46.454SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Extended phylogeny of the equine arteritis virus sequences including South American sequences
title Extended phylogeny of the equine arteritis virus sequences including South American sequences
spellingShingle Extended phylogeny of the equine arteritis virus sequences including South American sequences
Metz, Germán Ernesto
Ciencias Veterinarias
Equine arteritis virus
Equine arteritis, Argentina
Phylogenetic analysis
title_short Extended phylogeny of the equine arteritis virus sequences including South American sequences
title_full Extended phylogeny of the equine arteritis virus sequences including South American sequences
title_fullStr Extended phylogeny of the equine arteritis virus sequences including South American sequences
title_full_unstemmed Extended phylogeny of the equine arteritis virus sequences including South American sequences
title_sort Extended phylogeny of the equine arteritis virus sequences including South American sequences
dc.creator.none.fl_str_mv Metz, Germán Ernesto
Martín Ocampos, Giselle Paula
Serena, María Soledad
Gambaro, Sabrina Eliana
Nosetto, Edgardo Omar
Echeverría, María Gabriela
author Metz, Germán Ernesto
author_facet Metz, Germán Ernesto
Martín Ocampos, Giselle Paula
Serena, María Soledad
Gambaro, Sabrina Eliana
Nosetto, Edgardo Omar
Echeverría, María Gabriela
author_role author
author2 Martín Ocampos, Giselle Paula
Serena, María Soledad
Gambaro, Sabrina Eliana
Nosetto, Edgardo Omar
Echeverría, María Gabriela
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Veterinarias
Equine arteritis virus
Equine arteritis, Argentina
Phylogenetic analysis
topic Ciencias Veterinarias
Equine arteritis virus
Equine arteritis, Argentina
Phylogenetic analysis
dc.description.none.fl_txt_mv Objective: To perform genetic analysis of the ORF5 of equine arteritis virus (EAV) may provide new insights into the genetic evolution and origin of the Argentinean EAV sequences. Methods: A total of 76 sequences were analyzed by neighbor joining (NJ), maximum parsimony and maximum likelihood algorithms. The analysis of the selective pressures was performed using the Tajima's test. Results: The trees showed similar topologies. Two clades were identified: the first clade was formed by strains isolated mainly from a donkey, whereas the second clade presented four large groups from different geographic regions exclusively from Equus caballus. In this clade, we identified a group formed by South African and another one by South American and European sequences. In the latter, the monophyletic group was formed by seven Argentinean sequences. In the NJ tree, we identified a group formed by six Argentinean sequences. The Tajima's test showed a D value of 1.73663, indicating that the sequences analyzed follow a neutral evolution model. Conclusion: We concluded that the Argentinean sequences have a paraphyletic origin and that the fixation of point mutation might follow the neutral model evolution; however, we identified purifying pressures that may be involved in the differentiation of the EAV sequences.
Facultad de Ciencias Veterinarias
description Objective: To perform genetic analysis of the ORF5 of equine arteritis virus (EAV) may provide new insights into the genetic evolution and origin of the Argentinean EAV sequences. Methods: A total of 76 sequences were analyzed by neighbor joining (NJ), maximum parsimony and maximum likelihood algorithms. The analysis of the selective pressures was performed using the Tajima's test. Results: The trees showed similar topologies. Two clades were identified: the first clade was formed by strains isolated mainly from a donkey, whereas the second clade presented four large groups from different geographic regions exclusively from Equus caballus. In this clade, we identified a group formed by South African and another one by South American and European sequences. In the latter, the monophyletic group was formed by seven Argentinean sequences. In the NJ tree, we identified a group formed by six Argentinean sequences. The Tajima's test showed a D value of 1.73663, indicating that the sequences analyzed follow a neutral evolution model. Conclusion: We concluded that the Argentinean sequences have a paraphyletic origin and that the fixation of point mutation might follow the neutral model evolution; however, we identified purifying pressures that may be involved in the differentiation of the EAV sequences.
publishDate 2010
dc.date.none.fl_str_mv 2010
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/82438
url http://sedici.unlp.edu.ar/handle/10915/82438
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0300-5526
info:eu-repo/semantics/altIdentifier/doi/10.1159/000318925
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
30-36
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.13397

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