Pharmaceuticals and personal care products in the environment: What are the big questions?

Autores
Boxall, Alistair B. A.; Rudd, Murray A.; Brooks, Bryan W.; Caldwell, Daniel J.; Choi, Kyungho; Hickmann, Silke; Innes, Elizabeth; Ostapyk, Kim; Staveley, Jane P.; Verslycke, Tim; Ankley, Gerald T.; Beazley, Karen F.; Belanger, Scott E.; Berninger, Jason P.; Carriquiriborde, Pedro; Coors, Anja; DeLeo, Paul C.; Dyer, Scott D.; Ericson, Jon F.; Gagné, François; Giesy, John P.; Gouin, Todd; Hallstrom, Lars; Karlsson, Maja V.; Joakim Larsson, D.G.; Lazorchak, James M.; Mastrocco, Frank; McLaughlin, Alison; McMaster, Mark E.; Meyerhoff, Roger D.; Moore, Roberta; Parrott, Joanne L.; Snape, Jason R.; Murray-Smith, Richard; Servos, Mark R.; Sibley, Paul K.; Straub, Jürg Oliver; Szabo, Nora D.; Topp, Edward; Tetreault, Gerald R.; Trudeau, Vance L.; Van Der Kraak, Glen
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
Centro de Investigaciones del Medioambiente
Materia
Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/96195

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network_name_str SEDICI (UNLP)
spelling Pharmaceuticals and personal care products in the environment: What are the big questions?Boxall, Alistair B. A.Rudd, Murray A.Brooks, Bryan W.Caldwell, Daniel J.Choi, KyunghoHickmann, SilkeInnes, ElizabethOstapyk, KimStaveley, Jane P.Verslycke, TimAnkley, Gerald T.Beazley, Karen F.Belanger, Scott E.Berninger, Jason P.Carriquiriborde, PedroCoors, AnjaDeLeo, Paul C.Dyer, Scott D.Ericson, Jon F.Gagné, FrançoisGiesy, John P.Gouin, ToddHallstrom, LarsKarlsson, Maja V.Joakim Larsson, D.G.Lazorchak, James M.Mastrocco, FrankMcLaughlin, AlisonMcMaster, Mark E.Meyerhoff, Roger D.Moore, RobertaParrott, Joanne L.Snape, Jason R.Murray-Smith, RichardServos, Mark R.Sibley, Paul K.Straub, Jürg OliverSzabo, Nora D.Topp, EdwardTetreault, Gerald R.Trudeau, Vance L.Van Der Kraak, GlenBiologíaAntibiotic resistanceEcotoxicityExposure assessmentHealth effectsPersonal care productsPharmaceuticalsPrioritizationRisk assessmentRisk managementBackground: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.Centro de Investigaciones del Medioambiente2012-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf1221-1229http://sedici.unlp.edu.ar/handle/10915/96195enginfo:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/81809info:eu-repo/semantics/altIdentifier/url/https://ehp.niehs.nih.gov/doi/10.1289/ehp.1104477info:eu-repo/semantics/altIdentifier/issn/0091-6765info:eu-repo/semantics/altIdentifier/doi/10.1289/ehp.1104477info:eu-repo/semantics/altIdentifier/hdl/11336/81809info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:20:26Zoai:sedici.unlp.edu.ar:10915/96195Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:20:27.052SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Pharmaceuticals and personal care products in the environment: What are the big questions?
title Pharmaceuticals and personal care products in the environment: What are the big questions?
spellingShingle Pharmaceuticals and personal care products in the environment: What are the big questions?
Boxall, Alistair B. A.
Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
title_short Pharmaceuticals and personal care products in the environment: What are the big questions?
title_full Pharmaceuticals and personal care products in the environment: What are the big questions?
title_fullStr Pharmaceuticals and personal care products in the environment: What are the big questions?
title_full_unstemmed Pharmaceuticals and personal care products in the environment: What are the big questions?
title_sort Pharmaceuticals and personal care products in the environment: What are the big questions?
dc.creator.none.fl_str_mv Boxall, Alistair B. A.
Rudd, Murray A.
Brooks, Bryan W.
Caldwell, Daniel J.
Choi, Kyungho
Hickmann, Silke
Innes, Elizabeth
Ostapyk, Kim
Staveley, Jane P.
Verslycke, Tim
Ankley, Gerald T.
Beazley, Karen F.
Belanger, Scott E.
Berninger, Jason P.
Carriquiriborde, Pedro
Coors, Anja
DeLeo, Paul C.
Dyer, Scott D.
Ericson, Jon F.
Gagné, François
Giesy, John P.
Gouin, Todd
Hallstrom, Lars
Karlsson, Maja V.
Joakim Larsson, D.G.
Lazorchak, James M.
Mastrocco, Frank
McLaughlin, Alison
McMaster, Mark E.
Meyerhoff, Roger D.
Moore, Roberta
Parrott, Joanne L.
Snape, Jason R.
Murray-Smith, Richard
Servos, Mark R.
Sibley, Paul K.
Straub, Jürg Oliver
Szabo, Nora D.
Topp, Edward
Tetreault, Gerald R.
Trudeau, Vance L.
Van Der Kraak, Glen
author Boxall, Alistair B. A.
author_facet Boxall, Alistair B. A.
Rudd, Murray A.
Brooks, Bryan W.
Caldwell, Daniel J.
Choi, Kyungho
Hickmann, Silke
Innes, Elizabeth
Ostapyk, Kim
Staveley, Jane P.
Verslycke, Tim
Ankley, Gerald T.
Beazley, Karen F.
Belanger, Scott E.
Berninger, Jason P.
Carriquiriborde, Pedro
Coors, Anja
DeLeo, Paul C.
Dyer, Scott D.
Ericson, Jon F.
Gagné, François
Giesy, John P.
Gouin, Todd
Hallstrom, Lars
Karlsson, Maja V.
Joakim Larsson, D.G.
Lazorchak, James M.
Mastrocco, Frank
McLaughlin, Alison
McMaster, Mark E.
Meyerhoff, Roger D.
Moore, Roberta
Parrott, Joanne L.
Snape, Jason R.
Murray-Smith, Richard
Servos, Mark R.
Sibley, Paul K.
Straub, Jürg Oliver
Szabo, Nora D.
Topp, Edward
Tetreault, Gerald R.
Trudeau, Vance L.
Van Der Kraak, Glen
author_role author
author2 Rudd, Murray A.
Brooks, Bryan W.
Caldwell, Daniel J.
Choi, Kyungho
Hickmann, Silke
Innes, Elizabeth
Ostapyk, Kim
Staveley, Jane P.
Verslycke, Tim
Ankley, Gerald T.
Beazley, Karen F.
Belanger, Scott E.
Berninger, Jason P.
Carriquiriborde, Pedro
Coors, Anja
DeLeo, Paul C.
Dyer, Scott D.
Ericson, Jon F.
Gagné, François
Giesy, John P.
Gouin, Todd
Hallstrom, Lars
Karlsson, Maja V.
Joakim Larsson, D.G.
Lazorchak, James M.
Mastrocco, Frank
McLaughlin, Alison
McMaster, Mark E.
Meyerhoff, Roger D.
Moore, Roberta
Parrott, Joanne L.
Snape, Jason R.
Murray-Smith, Richard
Servos, Mark R.
Sibley, Paul K.
Straub, Jürg Oliver
Szabo, Nora D.
Topp, Edward
Tetreault, Gerald R.
Trudeau, Vance L.
Van Der Kraak, Glen
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
topic Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
dc.description.none.fl_txt_mv Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
Centro de Investigaciones del Medioambiente
description Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
publishDate 2012
dc.date.none.fl_str_mv 2012-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/96195
url http://sedici.unlp.edu.ar/handle/10915/96195
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/81809
info:eu-repo/semantics/altIdentifier/url/https://ehp.niehs.nih.gov/doi/10.1289/ehp.1104477
info:eu-repo/semantics/altIdentifier/issn/0091-6765
info:eu-repo/semantics/altIdentifier/doi/10.1289/ehp.1104477
info:eu-repo/semantics/altIdentifier/hdl/11336/81809
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
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instname:Universidad Nacional de La Plata
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repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
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