Pharmaceuticals and personal care products in the environment: What are the big questions?
- Autores
- Boxall, Alistair B. A.; Rudd, Murray A.; Brooks, Bryan W.; Caldwell, Daniel J.; Choi, Kyungho; Hickmann, Silke; Innes, Elizabeth; Ostapyk, Kim; Staveley, Jane P.; Verslycke, Tim; Ankley, Gerald T.; Beazley, Karen F.; Belanger, Scott E.; Berninger, Jason P.; Carriquiriborde, Pedro; Coors, Anja; DeLeo, Paul C.; Dyer, Scott D.; Ericson, Jon F.; Gagné, François; Giesy, John P.; Gouin, Todd; Hallstrom, Lars; Karlsson, Maja V.; Joakim Larsson, D.G.; Lazorchak, James M.; Mastrocco, Frank; McLaughlin, Alison; McMaster, Mark E.; Meyerhoff, Roger D.; Moore, Roberta; Parrott, Joanne L.; Snape, Jason R.; Murray-Smith, Richard; Servos, Mark R.; Sibley, Paul K.; Straub, Jürg Oliver; Szabo, Nora D.; Topp, Edward; Tetreault, Gerald R.; Trudeau, Vance L.; Van Der Kraak, Glen
- Año de publicación
- 2012
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
Centro de Investigaciones del Medioambiente - Materia
-
Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
- Institución
- Universidad Nacional de La Plata
- OAI Identificador
- oai:sedici.unlp.edu.ar:10915/96195
Ver los metadatos del registro completo
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Pharmaceuticals and personal care products in the environment: What are the big questions?Boxall, Alistair B. A.Rudd, Murray A.Brooks, Bryan W.Caldwell, Daniel J.Choi, KyunghoHickmann, SilkeInnes, ElizabethOstapyk, KimStaveley, Jane P.Verslycke, TimAnkley, Gerald T.Beazley, Karen F.Belanger, Scott E.Berninger, Jason P.Carriquiriborde, PedroCoors, AnjaDeLeo, Paul C.Dyer, Scott D.Ericson, Jon F.Gagné, FrançoisGiesy, John P.Gouin, ToddHallstrom, LarsKarlsson, Maja V.Joakim Larsson, D.G.Lazorchak, James M.Mastrocco, FrankMcLaughlin, AlisonMcMaster, Mark E.Meyerhoff, Roger D.Moore, RobertaParrott, Joanne L.Snape, Jason R.Murray-Smith, RichardServos, Mark R.Sibley, Paul K.Straub, Jürg OliverSzabo, Nora D.Topp, EdwardTetreault, Gerald R.Trudeau, Vance L.Van Der Kraak, GlenBiologíaAntibiotic resistanceEcotoxicityExposure assessmentHealth effectsPersonal care productsPharmaceuticalsPrioritizationRisk assessmentRisk managementBackground: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.Centro de Investigaciones del Medioambiente2012-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf1221-1229http://sedici.unlp.edu.ar/handle/10915/96195enginfo:eu-repo/semantics/altIdentifier/url/https://ri.conicet.gov.ar/11336/81809info:eu-repo/semantics/altIdentifier/url/https://ehp.niehs.nih.gov/doi/10.1289/ehp.1104477info:eu-repo/semantics/altIdentifier/issn/0091-6765info:eu-repo/semantics/altIdentifier/doi/10.1289/ehp.1104477info:eu-repo/semantics/altIdentifier/hdl/11336/81809info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:20:26Zoai:sedici.unlp.edu.ar:10915/96195Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:20:27.052SEDICI (UNLP) - Universidad Nacional de La Platafalse |
dc.title.none.fl_str_mv |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
title |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
spellingShingle |
Pharmaceuticals and personal care products in the environment: What are the big questions? Boxall, Alistair B. A. Biología Antibiotic resistance Ecotoxicity Exposure assessment Health effects Personal care products Pharmaceuticals Prioritization Risk assessment Risk management |
title_short |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
title_full |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
title_fullStr |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
title_full_unstemmed |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
title_sort |
Pharmaceuticals and personal care products in the environment: What are the big questions? |
dc.creator.none.fl_str_mv |
Boxall, Alistair B. A. Rudd, Murray A. Brooks, Bryan W. Caldwell, Daniel J. Choi, Kyungho Hickmann, Silke Innes, Elizabeth Ostapyk, Kim Staveley, Jane P. Verslycke, Tim Ankley, Gerald T. Beazley, Karen F. Belanger, Scott E. Berninger, Jason P. Carriquiriborde, Pedro Coors, Anja DeLeo, Paul C. Dyer, Scott D. Ericson, Jon F. Gagné, François Giesy, John P. Gouin, Todd Hallstrom, Lars Karlsson, Maja V. Joakim Larsson, D.G. Lazorchak, James M. Mastrocco, Frank McLaughlin, Alison McMaster, Mark E. Meyerhoff, Roger D. Moore, Roberta Parrott, Joanne L. Snape, Jason R. Murray-Smith, Richard Servos, Mark R. Sibley, Paul K. Straub, Jürg Oliver Szabo, Nora D. Topp, Edward Tetreault, Gerald R. Trudeau, Vance L. Van Der Kraak, Glen |
author |
Boxall, Alistair B. A. |
author_facet |
Boxall, Alistair B. A. Rudd, Murray A. Brooks, Bryan W. Caldwell, Daniel J. Choi, Kyungho Hickmann, Silke Innes, Elizabeth Ostapyk, Kim Staveley, Jane P. Verslycke, Tim Ankley, Gerald T. Beazley, Karen F. Belanger, Scott E. Berninger, Jason P. Carriquiriborde, Pedro Coors, Anja DeLeo, Paul C. Dyer, Scott D. Ericson, Jon F. Gagné, François Giesy, John P. Gouin, Todd Hallstrom, Lars Karlsson, Maja V. Joakim Larsson, D.G. Lazorchak, James M. Mastrocco, Frank McLaughlin, Alison McMaster, Mark E. Meyerhoff, Roger D. Moore, Roberta Parrott, Joanne L. Snape, Jason R. Murray-Smith, Richard Servos, Mark R. Sibley, Paul K. Straub, Jürg Oliver Szabo, Nora D. Topp, Edward Tetreault, Gerald R. Trudeau, Vance L. Van Der Kraak, Glen |
author_role |
author |
author2 |
Rudd, Murray A. Brooks, Bryan W. Caldwell, Daniel J. Choi, Kyungho Hickmann, Silke Innes, Elizabeth Ostapyk, Kim Staveley, Jane P. Verslycke, Tim Ankley, Gerald T. Beazley, Karen F. Belanger, Scott E. Berninger, Jason P. Carriquiriborde, Pedro Coors, Anja DeLeo, Paul C. Dyer, Scott D. Ericson, Jon F. Gagné, François Giesy, John P. Gouin, Todd Hallstrom, Lars Karlsson, Maja V. Joakim Larsson, D.G. Lazorchak, James M. Mastrocco, Frank McLaughlin, Alison McMaster, Mark E. Meyerhoff, Roger D. Moore, Roberta Parrott, Joanne L. Snape, Jason R. Murray-Smith, Richard Servos, Mark R. Sibley, Paul K. Straub, Jürg Oliver Szabo, Nora D. Topp, Edward Tetreault, Gerald R. Trudeau, Vance L. Van Der Kraak, Glen |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.subject.none.fl_str_mv |
Biología Antibiotic resistance Ecotoxicity Exposure assessment Health effects Personal care products Pharmaceuticals Prioritization Risk assessment Risk management |
topic |
Biología Antibiotic resistance Ecotoxicity Exposure assessment Health effects Personal care products Pharmaceuticals Prioritization Risk assessment Risk management |
dc.description.none.fl_txt_mv |
Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic. Centro de Investigaciones del Medioambiente |
description |
Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-05 |
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article |
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eng |
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eng |
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