Genetic diversity of Dioctophyme renale in Southern South America

Autores
Arce, Lucas F.; Facelli Fernández, Florencia; Giorello, Nahili; Butti, Marcos Javier; Maldonado, Lucas; Arrabal, Juan Pablo; Natalini, María B.; Kowalewski, Martín M.; Pedrassani, Daniela; Silveira Mascarenhas, Carol; da Silva Rappeti, Josaine Cristina; Zilli, Florencia Lucila; Beldoménico, Pablo M.; Lia, Verónica; Franchini, Gisela Raquel; Kamenetzky, Laura
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Dioctophyme renale, the giant kidney worm, is a nematode related to Trichuris sp and is distributed worldwide. These parasites locate in the kidney of their definitive hosts (mainly belonging to the order Carnivora) and have an indirect life cycle with an annelid as the main intermediate host. Humans are rarely affected, but in those that are, 1 or both kidneys are destroyed. In South America, D. renale is widespread in riparian regions where changing climatic conditions, environmental degradation, and compromised sanitation are increasing the risk of distribution of this parasite, including humans. Here, we provide the descriptions of the genetic diversity of the parasite in the region by analysing 73 adult D. renale samples collected from domestic and wild carnivores. The most common hosts were (Canis lupus familiaris) and maned wolf (Chrysocyon brachyurus Fam. Canidae) among domestic and wild carnivores, respectively. This work shows the descriptions of the genetic diversity of this parasite complementing molecular methods and classical and probabilistic phylogeography. Our results strongly suggest that this parasite has been present on the continent long enough to develop local genetic variants. Also, the phylogenies show transmission between localities and bidirectional transmission between domestic and wild species. We now have new tools to understand the ecological dynamics of this parasite such as molecular markers to study its genetic diversity as well as for identification and reporting in cryptic cases.
Facultad de Ciencias Veterinarias
Instituto de Investigaciones Bioquímicas de La Plata
Materia
Biología
COX1
Dioctophyme
Kidney parasite nematode
Mitochondrial
ND4
Phylogeography
Wild carnivores
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/193527

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network_name_str SEDICI (UNLP)
spelling Genetic diversity of Dioctophyme renale in Southern South AmericaArce, Lucas F.Facelli Fernández, FlorenciaGiorello, NahiliButti, Marcos JavierMaldonado, LucasArrabal, Juan PabloNatalini, María B.Kowalewski, Martín M.Pedrassani, DanielaSilveira Mascarenhas, Carolda Silva Rappeti, Josaine CristinaZilli, Florencia LucilaBeldoménico, Pablo M.Lia, VerónicaFranchini, Gisela RaquelKamenetzky, LauraBiologíaCOX1DioctophymeKidney parasite nematodeMitochondrialND4PhylogeographyWild carnivoresDioctophyme renale, the giant kidney worm, is a nematode related to Trichuris sp and is distributed worldwide. These parasites locate in the kidney of their definitive hosts (mainly belonging to the order Carnivora) and have an indirect life cycle with an annelid as the main intermediate host. Humans are rarely affected, but in those that are, 1 or both kidneys are destroyed. In South America, D. renale is widespread in riparian regions where changing climatic conditions, environmental degradation, and compromised sanitation are increasing the risk of distribution of this parasite, including humans. Here, we provide the descriptions of the genetic diversity of the parasite in the region by analysing 73 adult D. renale samples collected from domestic and wild carnivores. The most common hosts were (Canis lupus familiaris) and maned wolf (Chrysocyon brachyurus Fam. Canidae) among domestic and wild carnivores, respectively. This work shows the descriptions of the genetic diversity of this parasite complementing molecular methods and classical and probabilistic phylogeography. Our results strongly suggest that this parasite has been present on the continent long enough to develop local genetic variants. Also, the phylogenies show transmission between localities and bidirectional transmission between domestic and wild species. We now have new tools to understand the ecological dynamics of this parasite such as molecular markers to study its genetic diversity as well as for identification and reporting in cryptic cases.Facultad de Ciencias VeterinariasInstituto de Investigaciones Bioquímicas de La Plata2024-10-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf776-786https://doi.org/10.1017/s0031182024001379http://sedici.unlp.edu.ar/handle/10915/193527enginfo:eu-repo/semantics/altIdentifier/url/https://www.cambridge.org/core/services/aop-cambridge-core/content/view/7034AF7A3EBD687F6E087D6B2B7F8F4D/S0031182024001379a.pdf/div-class-title-genetic-diversity-of-span-class-italic-dioctophyme-renale-span-in-southern-south-america-div.pdfinfo:eu-repo/semantics/altIdentifier/issn/0031-1820info:eu-repo/semantics/altIdentifier/issn/1469-8161info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2026-05-06T13:00:49Zoai:sedici.unlp.edu.ar:10915/193527Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292026-05-06 13:00:49.773SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Genetic diversity of Dioctophyme renale in Southern South America
title Genetic diversity of Dioctophyme renale in Southern South America
spellingShingle Genetic diversity of Dioctophyme renale in Southern South America
Arce, Lucas F.
Biología
COX1
Dioctophyme
Kidney parasite nematode
Mitochondrial
ND4
Phylogeography
Wild carnivores
title_short Genetic diversity of Dioctophyme renale in Southern South America
title_full Genetic diversity of Dioctophyme renale in Southern South America
title_fullStr Genetic diversity of Dioctophyme renale in Southern South America
title_full_unstemmed Genetic diversity of Dioctophyme renale in Southern South America
title_sort Genetic diversity of Dioctophyme renale in Southern South America
dc.creator.none.fl_str_mv Arce, Lucas F.
Facelli Fernández, Florencia
Giorello, Nahili
Butti, Marcos Javier
Maldonado, Lucas
Arrabal, Juan Pablo
Natalini, María B.
Kowalewski, Martín M.
Pedrassani, Daniela
Silveira Mascarenhas, Carol
da Silva Rappeti, Josaine Cristina
Zilli, Florencia Lucila
Beldoménico, Pablo M.
Lia, Verónica
Franchini, Gisela Raquel
Kamenetzky, Laura
author Arce, Lucas F.
author_facet Arce, Lucas F.
Facelli Fernández, Florencia
Giorello, Nahili
Butti, Marcos Javier
Maldonado, Lucas
Arrabal, Juan Pablo
Natalini, María B.
Kowalewski, Martín M.
Pedrassani, Daniela
Silveira Mascarenhas, Carol
da Silva Rappeti, Josaine Cristina
Zilli, Florencia Lucila
Beldoménico, Pablo M.
Lia, Verónica
Franchini, Gisela Raquel
Kamenetzky, Laura
author_role author
author2 Facelli Fernández, Florencia
Giorello, Nahili
Butti, Marcos Javier
Maldonado, Lucas
Arrabal, Juan Pablo
Natalini, María B.
Kowalewski, Martín M.
Pedrassani, Daniela
Silveira Mascarenhas, Carol
da Silva Rappeti, Josaine Cristina
Zilli, Florencia Lucila
Beldoménico, Pablo M.
Lia, Verónica
Franchini, Gisela Raquel
Kamenetzky, Laura
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Biología
COX1
Dioctophyme
Kidney parasite nematode
Mitochondrial
ND4
Phylogeography
Wild carnivores
topic Biología
COX1
Dioctophyme
Kidney parasite nematode
Mitochondrial
ND4
Phylogeography
Wild carnivores
dc.description.none.fl_txt_mv Dioctophyme renale, the giant kidney worm, is a nematode related to Trichuris sp and is distributed worldwide. These parasites locate in the kidney of their definitive hosts (mainly belonging to the order Carnivora) and have an indirect life cycle with an annelid as the main intermediate host. Humans are rarely affected, but in those that are, 1 or both kidneys are destroyed. In South America, D. renale is widespread in riparian regions where changing climatic conditions, environmental degradation, and compromised sanitation are increasing the risk of distribution of this parasite, including humans. Here, we provide the descriptions of the genetic diversity of the parasite in the region by analysing 73 adult D. renale samples collected from domestic and wild carnivores. The most common hosts were (Canis lupus familiaris) and maned wolf (Chrysocyon brachyurus Fam. Canidae) among domestic and wild carnivores, respectively. This work shows the descriptions of the genetic diversity of this parasite complementing molecular methods and classical and probabilistic phylogeography. Our results strongly suggest that this parasite has been present on the continent long enough to develop local genetic variants. Also, the phylogenies show transmission between localities and bidirectional transmission between domestic and wild species. We now have new tools to understand the ecological dynamics of this parasite such as molecular markers to study its genetic diversity as well as for identification and reporting in cryptic cases.
Facultad de Ciencias Veterinarias
Instituto de Investigaciones Bioquímicas de La Plata
description Dioctophyme renale, the giant kidney worm, is a nematode related to Trichuris sp and is distributed worldwide. These parasites locate in the kidney of their definitive hosts (mainly belonging to the order Carnivora) and have an indirect life cycle with an annelid as the main intermediate host. Humans are rarely affected, but in those that are, 1 or both kidneys are destroyed. In South America, D. renale is widespread in riparian regions where changing climatic conditions, environmental degradation, and compromised sanitation are increasing the risk of distribution of this parasite, including humans. Here, we provide the descriptions of the genetic diversity of the parasite in the region by analysing 73 adult D. renale samples collected from domestic and wild carnivores. The most common hosts were (Canis lupus familiaris) and maned wolf (Chrysocyon brachyurus Fam. Canidae) among domestic and wild carnivores, respectively. This work shows the descriptions of the genetic diversity of this parasite complementing molecular methods and classical and probabilistic phylogeography. Our results strongly suggest that this parasite has been present on the continent long enough to develop local genetic variants. Also, the phylogenies show transmission between localities and bidirectional transmission between domestic and wild species. We now have new tools to understand the ecological dynamics of this parasite such as molecular markers to study its genetic diversity as well as for identification and reporting in cryptic cases.
publishDate 2024
dc.date.none.fl_str_mv 2024-10-28
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
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info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1017/s0031182024001379
http://sedici.unlp.edu.ar/handle/10915/193527
url https://doi.org/10.1017/s0031182024001379
http://sedici.unlp.edu.ar/handle/10915/193527
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/issn/0031-1820
info:eu-repo/semantics/altIdentifier/issn/1469-8161
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
776-786
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repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
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