Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes

Autores
Asturias Arribas, Laura; Delfino, Mario Raúl; Alonso Lomillo, María Asunción; Domínguez Renedo, Olga
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Asturias Arribas, Laura. Universidad de Burgos. Facultad de Ciencias; España.
Fil: Delfino, Mario Raúl. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina.
Fil: Delfino, Mario Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico; Argentina.
Fil: Alonso Lomillo, María Asunción. Universidad de Burgos. Facultad de Ciencias; España.
Fil: Domínguez Renedo, Olga. Universidad de Burgos. Facultad de Ciencias; España.
Fil: Arcos Martínez, María Julia. Universidad de Burgos. Facultad de Ciencias; España.
This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC.
Fuente
Electroanalysis, 2016, vol. 28, no. 9, p. 1-7.
Materia
Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
Institución
Universidad Nacional del Nordeste
OAI Identificador
oai:repositorio.unne.edu.ar:123456789/28014
Acceder
id RIUNNE_7ff6848ff6dfdbba124320b339553151
oai_identifier_str oai:repositorio.unne.edu.ar:123456789/28014
network_acronym_str RIUNNE
repository_id_str 4871
network_name_str Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
spelling Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodesAsturias Arribas, LauraDelfino, Mario RaúlAlonso Lomillo, María AsunciónDomínguez Renedo, OlgaNelfinavirScreen-printed electrodeElectrochemical oxidationCarbon nanotubesFil: Asturias Arribas, Laura. Universidad de Burgos. Facultad de Ciencias; España.Fil: Delfino, Mario Raúl. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina.Fil: Delfino, Mario Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico; Argentina.Fil: Alonso Lomillo, María Asunción. Universidad de Burgos. Facultad de Ciencias; España.Fil: Domínguez Renedo, Olga. Universidad de Burgos. Facultad de Ciencias; España.Fil: Arcos Martínez, María Julia. Universidad de Burgos. Facultad de Ciencias; España.This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC.Wiley VCH Verlag2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfAsturias Arribas, Laura, et.al., 2016. Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes. Electroanalysis. Weinheim: Wiley VCH Verlag, vol. 28, no. 9, p. 1-7. ISSN 1040-0397.1040-0397http://repositorio.unne.edu.ar/handle/123456789/28014Electroanalysis, 2016, vol. 28, no. 9, p. 1-7.reponame:Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)instname:Universidad Nacional del Nordesteenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/ar/Atribución-NoComercial-SinDerivadas 2.5 Argentina2025-09-04T11:13:02Zoai:repositorio.unne.edu.ar:123456789/28014instacron:UNNEInstitucionalhttp://repositorio.unne.edu.ar/Universidad públicaNo correspondehttp://repositorio.unne.edu.ar/oaiososa@bib.unne.edu.ar;sergio.alegria@unne.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:48712025-09-04 11:13:03.102Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE) - Universidad Nacional del Nordestefalse
dc.title.none.fl_str_mv Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
spellingShingle Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
Asturias Arribas, Laura
Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
title_short Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_full Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_fullStr Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_full_unstemmed Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
title_sort Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes
dc.creator.none.fl_str_mv Asturias Arribas, Laura
Delfino, Mario Raúl
Alonso Lomillo, María Asunción
Domínguez Renedo, Olga
author Asturias Arribas, Laura
author_facet Asturias Arribas, Laura
Delfino, Mario Raúl
Alonso Lomillo, María Asunción
Domínguez Renedo, Olga
author_role author
author2 Delfino, Mario Raúl
Alonso Lomillo, María Asunción
Domínguez Renedo, Olga
author2_role author
author
author
dc.subject.none.fl_str_mv Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
topic Nelfinavir
Screen-printed electrode
Electrochemical oxidation
Carbon nanotubes
dc.description.none.fl_txt_mv Fil: Asturias Arribas, Laura. Universidad de Burgos. Facultad de Ciencias; España.
Fil: Delfino, Mario Raúl. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina.
Fil: Delfino, Mario Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico; Argentina.
Fil: Alonso Lomillo, María Asunción. Universidad de Burgos. Facultad de Ciencias; España.
Fil: Domínguez Renedo, Olga. Universidad de Burgos. Facultad de Ciencias; España.
Fil: Arcos Martínez, María Julia. Universidad de Burgos. Facultad de Ciencias; España.
This paper describes the voltammetric study of the electrochemical oxidation of the antiretroviral drug Nelfinavir using a screen-printed sensor modified with carbon nanotubes. The performance of the sensor in the determination of the drug was characterized in terms of precision (RSD 5.05%, n=5) and capability of detection (10.99_0.87 mM for a=b=0.05, n=5) under optimized voltammetric conditions of pH, accumulation time and potential, in the calibration range from 10 to 150 mM of NFV. In order to check the viability of the device, the determination of the analyte in pharmaceutical and biological samples was carried out and its performance was also validated comparing it with HPLC.
description Fil: Asturias Arribas, Laura. Universidad de Burgos. Facultad de Ciencias; España.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv Asturias Arribas, Laura, et.al., 2016. Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes. Electroanalysis. Weinheim: Wiley VCH Verlag, vol. 28, no. 9, p. 1-7. ISSN 1040-0397.
1040-0397
http://repositorio.unne.edu.ar/handle/123456789/28014
identifier_str_mv Asturias Arribas, Laura, et.al., 2016. Electrochemical oxidation of the antiretroviral drug nelfinavir on modified screen-printed electrodes. Electroanalysis. Weinheim: Wiley VCH Verlag, vol. 28, no. 9, p. 1-7. ISSN 1040-0397.
1040-0397
url http://repositorio.unne.edu.ar/handle/123456789/28014
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Atribución-NoComercial-SinDerivadas 2.5 Argentina
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Atribución-NoComercial-SinDerivadas 2.5 Argentina
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley VCH Verlag
publisher.none.fl_str_mv Wiley VCH Verlag
dc.source.none.fl_str_mv Electroanalysis, 2016, vol. 28, no. 9, p. 1-7.
reponame:Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
instname:Universidad Nacional del Nordeste
reponame_str Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
collection Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE)
instname_str Universidad Nacional del Nordeste
repository.name.fl_str_mv Repositorio Institucional de la Universidad Nacional del Nordeste (UNNE) - Universidad Nacional del Nordeste
repository.mail.fl_str_mv ososa@bib.unne.edu.ar;sergio.alegria@unne.edu.ar
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score 12.623145

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