Timing is everything : circadian rhythms and their role in the control of sleep
- Autores
- Cardinali, Daniel Pedro; Pandi Perumal, Seithikurippu R.; Zaki, Nevin F. W.; Karthikeyan, Ramanujam; Spence, David Warren; Reiter, R.; Brown, Gregory M.
- Año de publicación
- 2022
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión aceptada
- Descripción
- Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina
Fil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc; Canadá
Fil: Pandi Perumal, Seithikurippu R. Universidad Saveetha. Instituto Saveetha de Medicina y Ciencias Médicas. Hospital Universitario Saveetha; India
Fil: Zaki, Nevin F. W. Universidad de Mansoura. Facultad de Medicina. Departamento de Psiquiatría; Egipto
Fil: Karthikeyan, Ramanujam. Investigador independiente; India
Fil: Spence, David Warren. Investigador independiente; Canadá
Fil: Reiter, R. Universidad de Texas. Departamento de Sistemas Celulares y Anatomía; Estados Unidos
Fil: Brown, Gregory M. Univeridad de Toronto. Centro para la Adicción y la Salud Mental. Ciencias Moleculares del Cerebro; Canadá
Abstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology. - Fuente
- Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022
- Materia
-
SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO - Nivel de accesibilidad
- acceso embargado
- Condiciones de uso
- Repositorio
- Institución
- Pontificia Universidad Católica Argentina
- OAI Identificador
- oai:ucacris:123456789/13636
Ver los metadatos del registro completo
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Timing is everything : circadian rhythms and their role in the control of sleepCardinali, Daniel PedroPandi Perumal, Seithikurippu R.Zaki, Nevin F. W.Karthikeyan, RamanujamSpence, David WarrenReiter, R.Brown, Gregory M.SUEÑOMEDICINATRASTORNOS DEL SUEÑORITMO CIRCADIANOFil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; ArgentinaFil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc; CanadáFil: Pandi Perumal, Seithikurippu R. Universidad Saveetha. Instituto Saveetha de Medicina y Ciencias Médicas. Hospital Universitario Saveetha; IndiaFil: Zaki, Nevin F. W. Universidad de Mansoura. Facultad de Medicina. Departamento de Psiquiatría; EgiptoFil: Karthikeyan, Ramanujam. Investigador independiente; IndiaFil: Spence, David Warren. Investigador independiente; CanadáFil: Reiter, R. Universidad de Texas. Departamento de Sistemas Celulares y Anatomía; Estados UnidosFil: Brown, Gregory M. Univeridad de Toronto. Centro para la Adicción y la Salud Mental. Ciencias Moleculares del Cerebro; CanadáAbstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology.ElsevierInternational Neuroendocrine Federation0000-0002-8686-7259info:eu-repo/date/embargoEnd/2024-01-012022info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/136360091- 3022 (impreso)1095-6808 (on line)10.1016/j.yfrne.2022.100978Pandi-Perumal, S. R., Cardinali, D., Zaki, N.F. W. et al. Timing is everything : circadian rhythms and their role in the control of sleep [en línea]. Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022. doi: 10.1016/j.yfrne.2022.100978. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13636Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/embargoedAccess2025-07-03T10:58:28Zoai:ucacris:123456789/13636instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:58:28.863Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse |
dc.title.none.fl_str_mv |
Timing is everything : circadian rhythms and their role in the control of sleep |
title |
Timing is everything : circadian rhythms and their role in the control of sleep |
spellingShingle |
Timing is everything : circadian rhythms and their role in the control of sleep Cardinali, Daniel Pedro SUEÑO MEDICINA TRASTORNOS DEL SUEÑO RITMO CIRCADIANO |
title_short |
Timing is everything : circadian rhythms and their role in the control of sleep |
title_full |
Timing is everything : circadian rhythms and their role in the control of sleep |
title_fullStr |
Timing is everything : circadian rhythms and their role in the control of sleep |
title_full_unstemmed |
Timing is everything : circadian rhythms and their role in the control of sleep |
title_sort |
Timing is everything : circadian rhythms and their role in the control of sleep |
dc.creator.none.fl_str_mv |
Cardinali, Daniel Pedro Pandi Perumal, Seithikurippu R. Zaki, Nevin F. W. Karthikeyan, Ramanujam Spence, David Warren Reiter, R. Brown, Gregory M. |
author |
Cardinali, Daniel Pedro |
author_facet |
Cardinali, Daniel Pedro Pandi Perumal, Seithikurippu R. Zaki, Nevin F. W. Karthikeyan, Ramanujam Spence, David Warren Reiter, R. Brown, Gregory M. |
author_role |
author |
author2 |
Pandi Perumal, Seithikurippu R. Zaki, Nevin F. W. Karthikeyan, Ramanujam Spence, David Warren Reiter, R. Brown, Gregory M. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
0000-0002-8686-7259 |
dc.subject.none.fl_str_mv |
SUEÑO MEDICINA TRASTORNOS DEL SUEÑO RITMO CIRCADIANO |
topic |
SUEÑO MEDICINA TRASTORNOS DEL SUEÑO RITMO CIRCADIANO |
dc.description.none.fl_txt_mv |
Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina Fil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc; Canadá Fil: Pandi Perumal, Seithikurippu R. Universidad Saveetha. Instituto Saveetha de Medicina y Ciencias Médicas. Hospital Universitario Saveetha; India Fil: Zaki, Nevin F. W. Universidad de Mansoura. Facultad de Medicina. Departamento de Psiquiatría; Egipto Fil: Karthikeyan, Ramanujam. Investigador independiente; India Fil: Spence, David Warren. Investigador independiente; Canadá Fil: Reiter, R. Universidad de Texas. Departamento de Sistemas Celulares y Anatomía; Estados Unidos Fil: Brown, Gregory M. Univeridad de Toronto. Centro para la Adicción y la Salud Mental. Ciencias Moleculares del Cerebro; Canadá Abstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology. |
description |
Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022 info:eu-repo/date/embargoEnd/2024-01-01 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
acceptedVersion |
dc.identifier.none.fl_str_mv |
https://repositorio.uca.edu.ar/handle/123456789/13636 0091- 3022 (impreso) 1095-6808 (on line) 10.1016/j.yfrne.2022.100978 Pandi-Perumal, S. R., Cardinali, D., Zaki, N.F. W. et al. Timing is everything : circadian rhythms and their role in the control of sleep [en línea]. Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022. doi: 10.1016/j.yfrne.2022.100978. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13636 |
url |
https://repositorio.uca.edu.ar/handle/123456789/13636 |
identifier_str_mv |
0091- 3022 (impreso) 1095-6808 (on line) 10.1016/j.yfrne.2022.100978 Pandi-Perumal, S. R., Cardinali, D., Zaki, N.F. W. et al. Timing is everything : circadian rhythms and their role in the control of sleep [en línea]. Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022. doi: 10.1016/j.yfrne.2022.100978. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13636 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier International Neuroendocrine Federation |
publisher.none.fl_str_mv |
Elsevier International Neuroendocrine Federation |
dc.source.none.fl_str_mv |
Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022 reponame:Repositorio Institucional (UCA) instname:Pontificia Universidad Católica Argentina |
reponame_str |
Repositorio Institucional (UCA) |
collection |
Repositorio Institucional (UCA) |
instname_str |
Pontificia Universidad Católica Argentina |
repository.name.fl_str_mv |
Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina |
repository.mail.fl_str_mv |
claudia_fernandez@uca.edu.ar |
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1836638360980946944 |
score |
13.13397 |