Timing is everything : circadian rhythms and their role in the control of sleep

Autores
Cardinali, Daniel Pedro; Pandi Perumal, Seithikurippu R.; Zaki, Nevin F. W.; Karthikeyan, Ramanujam; Spence, David Warren; Reiter, R.; Brown, Gregory M.
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina
Fil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc; Canadá
Fil: Pandi Perumal, Seithikurippu R. Universidad Saveetha. Instituto Saveetha de Medicina y Ciencias Médicas. Hospital Universitario Saveetha; India
Fil: Zaki, Nevin F. W. Universidad de Mansoura. Facultad de Medicina. Departamento de Psiquiatría; Egipto
Fil: Karthikeyan, Ramanujam. Investigador independiente; India
Fil: Spence, David Warren. Investigador independiente; Canadá
Fil: Reiter, R. Universidad de Texas. Departamento de Sistemas Celulares y Anatomía; Estados Unidos
Fil: Brown, Gregory M. Univeridad de Toronto. Centro para la Adicción y la Salud Mental. Ciencias Moleculares del Cerebro; Canadá
Abstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology.
Fuente
Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022
Materia
SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
Nivel de accesibilidad
acceso embargado
Condiciones de uso
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/13636
Acceder
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oai_identifier_str oai:ucacris:123456789/13636
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Timing is everything : circadian rhythms and their role in the control of sleepCardinali, Daniel PedroPandi Perumal, Seithikurippu R.Zaki, Nevin F. W.Karthikeyan, RamanujamSpence, David WarrenReiter, R.Brown, Gregory M.SUEÑOMEDICINATRASTORNOS DEL SUEÑORITMO CIRCADIANOFil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; ArgentinaFil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc; CanadáFil: Pandi Perumal, Seithikurippu R. Universidad Saveetha. Instituto Saveetha de Medicina y Ciencias Médicas. Hospital Universitario Saveetha; IndiaFil: Zaki, Nevin F. W. Universidad de Mansoura. Facultad de Medicina. Departamento de Psiquiatría; EgiptoFil: Karthikeyan, Ramanujam. Investigador independiente; IndiaFil: Spence, David Warren. Investigador independiente; CanadáFil: Reiter, R. Universidad de Texas. Departamento de Sistemas Celulares y Anatomía; Estados UnidosFil: Brown, Gregory M. Univeridad de Toronto. Centro para la Adicción y la Salud Mental. Ciencias Moleculares del Cerebro; CanadáAbstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology.ElsevierInternational Neuroendocrine Federation0000-0002-8686-7259info:eu-repo/date/embargoEnd/2024-01-012022info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/136360091- 3022 (impreso)1095-6808 (on line)10.1016/j.yfrne.2022.100978Pandi-Perumal, S. R., Cardinali, D., Zaki, N.F. W. et al. Timing is everything : circadian rhythms and their role in the control of sleep [en línea]. Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022. doi: 10.1016/j.yfrne.2022.100978. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13636Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/embargoedAccess2025-07-03T10:58:28Zoai:ucacris:123456789/13636instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:58:28.863Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Timing is everything : circadian rhythms and their role in the control of sleep
title Timing is everything : circadian rhythms and their role in the control of sleep
spellingShingle Timing is everything : circadian rhythms and their role in the control of sleep
Cardinali, Daniel Pedro
SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
title_short Timing is everything : circadian rhythms and their role in the control of sleep
title_full Timing is everything : circadian rhythms and their role in the control of sleep
title_fullStr Timing is everything : circadian rhythms and their role in the control of sleep
title_full_unstemmed Timing is everything : circadian rhythms and their role in the control of sleep
title_sort Timing is everything : circadian rhythms and their role in the control of sleep
dc.creator.none.fl_str_mv Cardinali, Daniel Pedro
Pandi Perumal, Seithikurippu R.
Zaki, Nevin F. W.
Karthikeyan, Ramanujam
Spence, David Warren
Reiter, R.
Brown, Gregory M.
author Cardinali, Daniel Pedro
author_facet Cardinali, Daniel Pedro
Pandi Perumal, Seithikurippu R.
Zaki, Nevin F. W.
Karthikeyan, Ramanujam
Spence, David Warren
Reiter, R.
Brown, Gregory M.
author_role author
author2 Pandi Perumal, Seithikurippu R.
Zaki, Nevin F. W.
Karthikeyan, Ramanujam
Spence, David Warren
Reiter, R.
Brown, Gregory M.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv 0000-0002-8686-7259
dc.subject.none.fl_str_mv SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
topic SUEÑO
MEDICINA
TRASTORNOS DEL SUEÑO
RITMO CIRCADIANO
dc.description.none.fl_txt_mv Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina
Fil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc; Canadá
Fil: Pandi Perumal, Seithikurippu R. Universidad Saveetha. Instituto Saveetha de Medicina y Ciencias Médicas. Hospital Universitario Saveetha; India
Fil: Zaki, Nevin F. W. Universidad de Mansoura. Facultad de Medicina. Departamento de Psiquiatría; Egipto
Fil: Karthikeyan, Ramanujam. Investigador independiente; India
Fil: Spence, David Warren. Investigador independiente; Canadá
Fil: Reiter, R. Universidad de Texas. Departamento de Sistemas Celulares y Anatomía; Estados Unidos
Fil: Brown, Gregory M. Univeridad de Toronto. Centro para la Adicción y la Salud Mental. Ciencias Moleculares del Cerebro; Canadá
Abstract: Sleep and the circadian clock are intertwined and have persisted throughout history. The suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and homeostatic (Process S) activities. As a "hand" on the endogenous circadian clock, melatonin is critical for sleep regulation. Light serves as a cue for sleep/wake control by activating retino-recipient cells in the SCN and subsequently suppressing melatonin. Clock genes are the molecular timekeepers that keep the 24 h cycle in place. Two main sleep and behavioural disorder diagnostic manuals have now officially recognised the importance of these processes for human health and well-being. The body's ability to respond to daily demands with the least amount of effort is maximised by carefully timing and integrating all components of sleep and waking. In the brain, the organization of timing is essential for optimal brain physiology.
description Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas; Argentina
publishDate 2022
dc.date.none.fl_str_mv 2022
info:eu-repo/date/embargoEnd/2024-01-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/13636
0091- 3022 (impreso)
1095-6808 (on line)
10.1016/j.yfrne.2022.100978
Pandi-Perumal, S. R., Cardinali, D., Zaki, N.F. W. et al. Timing is everything : circadian rhythms and their role in the control of sleep [en línea]. Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022. doi: 10.1016/j.yfrne.2022.100978. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13636
url https://repositorio.uca.edu.ar/handle/123456789/13636
identifier_str_mv 0091- 3022 (impreso)
1095-6808 (on line)
10.1016/j.yfrne.2022.100978
Pandi-Perumal, S. R., Cardinali, D., Zaki, N.F. W. et al. Timing is everything : circadian rhythms and their role in the control of sleep [en línea]. Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022. doi: 10.1016/j.yfrne.2022.100978. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13636
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
International Neuroendocrine Federation
publisher.none.fl_str_mv Elsevier
International Neuroendocrine Federation
dc.source.none.fl_str_mv Postprint del artículo publicado en: Frontiers in Neuroendocrinology. 2022
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 13.069144

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