Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina
- Autores
- García-Witulski, Christian
- Año de publicación
- 2024
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Fil: García Witulski, Christian M. Pontificia Universidad Católica Argentina. Facultad de Ciencias Económicas. Centro de Desarrollo Humano Sostenible; Argentina
Fil: Universidad Espíritu Santo; Ecuador
Background: Although there is evidence that sitting time (ST) and insufficient physical activity (PA) are associated with premature mortality, the burden of cardiovascular disease (CVD) and all-cause mortality (ACM) attributable to the combined effects of ST and PA in counterfactual scenarios is limited. Methods: Potential impact fractions (PIFs) were used to calculate premature deaths (PDs) and disability-adjusted life years (DALYs). Cause-eliminated life tables were utilized to estimate health-adjusted life expectancy (HALE) gains. Monte Carlo simulations were performed for uncertainty analysis. Results: The theoretical minimum risk exposure level (ST < 4 , PA > 65 ) could prevent 16.7% of CVD deaths and 12.3% of all-cause deaths annually. This would save 669 to 2,630 DALYs per 100,000 and increase healthy life years by 0.57 to 2.94. Increasing PA to > 65 while maintaining ST could yield gains in HALE from 0.49 (CVD) to 2.60 (ACM) years. Reducing ST to < 4 while keeping PA constant could lead to gains in HALE from 0.07 (CVD) to 0.34 (ACM) years. A 50% reduction in suboptimal ST (≥ 4) doubled HALE gains, ranging from 0.11 to 0.63 years. Conclusions: Public health decision-makers should prioritize vulnerable populations, including older adults and individuals with inadequate PA levels. - Fuente
- Journal of Public Health. 47(1), 2024.
- Materia
-
MORTALIDAD
ENFERMEDADES CARDIOVASCULARES
SEDENTARISMO
ACTIVIDAD FISICA
EXPECTATIVA DE VIDA - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
- Institución
- Pontificia Universidad Católica Argentina
- OAI Identificador
- oai:ucacris:123456789/19906
Ver los metadatos del registro completo
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oai:ucacris:123456789/19906 |
network_acronym_str |
RIUCA |
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2585 |
network_name_str |
Repositorio Institucional (UCA) |
spelling |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from ArgentinaGarcía-Witulski, ChristianMORTALIDADENFERMEDADES CARDIOVASCULARESSEDENTARISMOACTIVIDAD FISICAEXPECTATIVA DE VIDAFil: García Witulski, Christian M. Pontificia Universidad Católica Argentina. Facultad de Ciencias Económicas. Centro de Desarrollo Humano Sostenible; ArgentinaFil: Universidad Espíritu Santo; EcuadorBackground: Although there is evidence that sitting time (ST) and insufficient physical activity (PA) are associated with premature mortality, the burden of cardiovascular disease (CVD) and all-cause mortality (ACM) attributable to the combined effects of ST and PA in counterfactual scenarios is limited. Methods: Potential impact fractions (PIFs) were used to calculate premature deaths (PDs) and disability-adjusted life years (DALYs). Cause-eliminated life tables were utilized to estimate health-adjusted life expectancy (HALE) gains. Monte Carlo simulations were performed for uncertainty analysis. Results: The theoretical minimum risk exposure level (ST < 4 , PA > 65 ) could prevent 16.7% of CVD deaths and 12.3% of all-cause deaths annually. This would save 669 to 2,630 DALYs per 100,000 and increase healthy life years by 0.57 to 2.94. Increasing PA to > 65 while maintaining ST could yield gains in HALE from 0.49 (CVD) to 2.60 (ACM) years. Reducing ST to < 4 while keeping PA constant could lead to gains in HALE from 0.07 (CVD) to 0.34 (ACM) years. A 50% reduction in suboptimal ST (≥ 4) doubled HALE gains, ranging from 0.11 to 0.63 years. Conclusions: Public health decision-makers should prioritize vulnerable populations, including older adults and individuals with inadequate PA levels.Oxford Academic2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/199061741-38501741-384210.1093/pubmed/fdae291Journal of Public Health. 47(1), 2024.reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T11:00:14Zoai:ucacris:123456789/19906instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 11:00:15.063Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse |
dc.title.none.fl_str_mv |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
title |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
spellingShingle |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina García-Witulski, Christian MORTALIDAD ENFERMEDADES CARDIOVASCULARES SEDENTARISMO ACTIVIDAD FISICA EXPECTATIVA DE VIDA |
title_short |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
title_full |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
title_fullStr |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
title_full_unstemmed |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
title_sort |
Comparative risk assessment modeling of cardiovascular and all-cause burden attributable to sitting time and physical inactivity: evidence from Argentina |
dc.creator.none.fl_str_mv |
García-Witulski, Christian |
author |
García-Witulski, Christian |
author_facet |
García-Witulski, Christian |
author_role |
author |
dc.subject.none.fl_str_mv |
MORTALIDAD ENFERMEDADES CARDIOVASCULARES SEDENTARISMO ACTIVIDAD FISICA EXPECTATIVA DE VIDA |
topic |
MORTALIDAD ENFERMEDADES CARDIOVASCULARES SEDENTARISMO ACTIVIDAD FISICA EXPECTATIVA DE VIDA |
dc.description.none.fl_txt_mv |
Fil: García Witulski, Christian M. Pontificia Universidad Católica Argentina. Facultad de Ciencias Económicas. Centro de Desarrollo Humano Sostenible; Argentina Fil: Universidad Espíritu Santo; Ecuador Background: Although there is evidence that sitting time (ST) and insufficient physical activity (PA) are associated with premature mortality, the burden of cardiovascular disease (CVD) and all-cause mortality (ACM) attributable to the combined effects of ST and PA in counterfactual scenarios is limited. Methods: Potential impact fractions (PIFs) were used to calculate premature deaths (PDs) and disability-adjusted life years (DALYs). Cause-eliminated life tables were utilized to estimate health-adjusted life expectancy (HALE) gains. Monte Carlo simulations were performed for uncertainty analysis. Results: The theoretical minimum risk exposure level (ST < 4 , PA > 65 ) could prevent 16.7% of CVD deaths and 12.3% of all-cause deaths annually. This would save 669 to 2,630 DALYs per 100,000 and increase healthy life years by 0.57 to 2.94. Increasing PA to > 65 while maintaining ST could yield gains in HALE from 0.49 (CVD) to 2.60 (ACM) years. Reducing ST to < 4 while keeping PA constant could lead to gains in HALE from 0.07 (CVD) to 0.34 (ACM) years. A 50% reduction in suboptimal ST (≥ 4) doubled HALE gains, ranging from 0.11 to 0.63 years. Conclusions: Public health decision-makers should prioritize vulnerable populations, including older adults and individuals with inadequate PA levels. |
description |
Fil: García Witulski, Christian M. Pontificia Universidad Católica Argentina. Facultad de Ciencias Económicas. Centro de Desarrollo Humano Sostenible; Argentina |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
https://repositorio.uca.edu.ar/handle/123456789/19906 1741-3850 1741-3842 10.1093/pubmed/fdae291 |
url |
https://repositorio.uca.edu.ar/handle/123456789/19906 |
identifier_str_mv |
1741-3850 1741-3842 10.1093/pubmed/fdae291 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Oxford Academic |
publisher.none.fl_str_mv |
Oxford Academic |
dc.source.none.fl_str_mv |
Journal of Public Health. 47(1), 2024. reponame:Repositorio Institucional (UCA) instname:Pontificia Universidad Católica Argentina |
reponame_str |
Repositorio Institucional (UCA) |
collection |
Repositorio Institucional (UCA) |
instname_str |
Pontificia Universidad Católica Argentina |
repository.name.fl_str_mv |
Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina |
repository.mail.fl_str_mv |
claudia_fernandez@uca.edu.ar |
_version_ |
1836638377434152960 |
score |
13.070432 |