Understanding the role of sleep and its disturbances in autism spectrum disorder
- Autores
- Karthikeyan, Ramanujam; Cardinali, Daniel Pedro; Shakunthala, Venkat; Spence, David Warren; Brown, Gregory M.; Pandi Perumal, Seithikurippu R.
- Año de publicación
- 2020
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión aceptada
- Descripción
- Fil: Karthikeyan, Ramanujam. School of Biological Sciences. Department of Animal Behavior & Physiology; India
Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Medicas; Argentina
Fil: Shakunthala, Venkat. University of Mysuru. Department of Zoology; India
Fil: Spence, David Warren. Independent Research Consultant; Canada
Fil: Brown, Gregory M. University of Toronto. Department of Psychiatry. Centre for Addiction and Mental Health. Molecular Brain Science; Canada
Fil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc.; Canada
Abstract: Sleep difficulties are one of the significant complications associated with autism spectrum disorder (ASD). Despite their possible role as contributors to the overall symptoms of ASD, the symptoms of disturbed sleep experienced by many affected patients have only recently started to receive attention from clinicians, caretakers, and family members. Many types of sleep disorders have been reported in ASD individuals, but these have not been categorized under a common terminology. Nevertheless, several studies have established that a positive relationship exists between the occurrence of sleep difficulties and heightenedsymptomatology in ASD children. When ASD children show evidence of sleep problems there is also an increased frequency of behavioral problems such as social impairment, decreased cognitive functioning, aggressiveness, and anxiety. Several hypotheses have been put forward regarding the linkage between disturbed sleep and ASD. These have included suggestions that sleep difficulties and other ASD symptoms are induced by disruption of the circadian clock, the presence of comorbid physical or psychological conditions, elevated anxiety levels, or emotional distress. This article reviews the use of sleep therapies in ASD, among which melatonin has shown promise because of its lack ofsignificant side effects. A better understanding of sleep problems in the etiology of ASD, their impact on the symptoms and behavior of ASD individuals, and their potential use as a secondary aid for treating ASD would represent a significant contribution todevelop strategies to manage the disorder. - Fuente
- International Journal of Neuroscience Vol. 130, No.10.2020
- Materia
-
TRASTORNO DEL ESPECTRO AUTISTA
TRASTORNOS DEL SUEÑO
MELATONINA
TRATAMIENTO TERAPEUTICO
AUTISMO - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
- Institución
- Pontificia Universidad Católica Argentina
- OAI Identificador
- oai:ucacris:123456789/13666
Ver los metadatos del registro completo
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Understanding the role of sleep and its disturbances in autism spectrum disorderKarthikeyan, RamanujamCardinali, Daniel PedroShakunthala, VenkatSpence, David WarrenBrown, Gregory M.Pandi Perumal, Seithikurippu R.TRASTORNO DEL ESPECTRO AUTISTATRASTORNOS DEL SUEÑOMELATONINATRATAMIENTO TERAPEUTICOAUTISMOFil: Karthikeyan, Ramanujam. School of Biological Sciences. Department of Animal Behavior & Physiology; IndiaFil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Medicas; ArgentinaFil: Shakunthala, Venkat. University of Mysuru. Department of Zoology; IndiaFil: Spence, David Warren. Independent Research Consultant; CanadaFil: Brown, Gregory M. University of Toronto. Department of Psychiatry. Centre for Addiction and Mental Health. Molecular Brain Science; CanadaFil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc.; CanadaAbstract: Sleep difficulties are one of the significant complications associated with autism spectrum disorder (ASD). Despite their possible role as contributors to the overall symptoms of ASD, the symptoms of disturbed sleep experienced by many affected patients have only recently started to receive attention from clinicians, caretakers, and family members. Many types of sleep disorders have been reported in ASD individuals, but these have not been categorized under a common terminology. Nevertheless, several studies have established that a positive relationship exists between the occurrence of sleep difficulties and heightenedsymptomatology in ASD children. When ASD children show evidence of sleep problems there is also an increased frequency of behavioral problems such as social impairment, decreased cognitive functioning, aggressiveness, and anxiety. Several hypotheses have been put forward regarding the linkage between disturbed sleep and ASD. These have included suggestions that sleep difficulties and other ASD symptoms are induced by disruption of the circadian clock, the presence of comorbid physical or psychological conditions, elevated anxiety levels, or emotional distress. This article reviews the use of sleep therapies in ASD, among which melatonin has shown promise because of its lack ofsignificant side effects. A better understanding of sleep problems in the etiology of ASD, their impact on the symptoms and behavior of ASD individuals, and their potential use as a secondary aid for treating ASD would represent a significant contribution todevelop strategies to manage the disorder.Taylor & Francis2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/136660020-74541543-5245 (online)10.1080/00207454.2019.1711377Karthikeyan, R., Cardinali, D. P., Shakunthala, V., Spence, D. W., Brown, G.M., Pandi Perumal, S. R. Understanding the role of sleep and its disturbances in autism spectrum disorder [en línea]. Postprint del artículo publicado en: International Journal of Neuroscience. 2020, 130 (10). doi: 10.1080/00207454.2019.1711377. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13666International Journal of Neuroscience Vol. 130, No.10.2020reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T10:58:30Zoai:ucacris:123456789/13666instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:58:30.364Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse |
dc.title.none.fl_str_mv |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
title |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
spellingShingle |
Understanding the role of sleep and its disturbances in autism spectrum disorder Karthikeyan, Ramanujam TRASTORNO DEL ESPECTRO AUTISTA TRASTORNOS DEL SUEÑO MELATONINA TRATAMIENTO TERAPEUTICO AUTISMO |
title_short |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
title_full |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
title_fullStr |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
title_full_unstemmed |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
title_sort |
Understanding the role of sleep and its disturbances in autism spectrum disorder |
dc.creator.none.fl_str_mv |
Karthikeyan, Ramanujam Cardinali, Daniel Pedro Shakunthala, Venkat Spence, David Warren Brown, Gregory M. Pandi Perumal, Seithikurippu R. |
author |
Karthikeyan, Ramanujam |
author_facet |
Karthikeyan, Ramanujam Cardinali, Daniel Pedro Shakunthala, Venkat Spence, David Warren Brown, Gregory M. Pandi Perumal, Seithikurippu R. |
author_role |
author |
author2 |
Cardinali, Daniel Pedro Shakunthala, Venkat Spence, David Warren Brown, Gregory M. Pandi Perumal, Seithikurippu R. |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
TRASTORNO DEL ESPECTRO AUTISTA TRASTORNOS DEL SUEÑO MELATONINA TRATAMIENTO TERAPEUTICO AUTISMO |
topic |
TRASTORNO DEL ESPECTRO AUTISTA TRASTORNOS DEL SUEÑO MELATONINA TRATAMIENTO TERAPEUTICO AUTISMO |
dc.description.none.fl_txt_mv |
Fil: Karthikeyan, Ramanujam. School of Biological Sciences. Department of Animal Behavior & Physiology; India Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Ciencias Medicas; Argentina Fil: Shakunthala, Venkat. University of Mysuru. Department of Zoology; India Fil: Spence, David Warren. Independent Research Consultant; Canada Fil: Brown, Gregory M. University of Toronto. Department of Psychiatry. Centre for Addiction and Mental Health. Molecular Brain Science; Canada Fil: Pandi Perumal, Seithikurippu R. Somnogen Canada Inc.; Canada Abstract: Sleep difficulties are one of the significant complications associated with autism spectrum disorder (ASD). Despite their possible role as contributors to the overall symptoms of ASD, the symptoms of disturbed sleep experienced by many affected patients have only recently started to receive attention from clinicians, caretakers, and family members. Many types of sleep disorders have been reported in ASD individuals, but these have not been categorized under a common terminology. Nevertheless, several studies have established that a positive relationship exists between the occurrence of sleep difficulties and heightenedsymptomatology in ASD children. When ASD children show evidence of sleep problems there is also an increased frequency of behavioral problems such as social impairment, decreased cognitive functioning, aggressiveness, and anxiety. Several hypotheses have been put forward regarding the linkage between disturbed sleep and ASD. These have included suggestions that sleep difficulties and other ASD symptoms are induced by disruption of the circadian clock, the presence of comorbid physical or psychological conditions, elevated anxiety levels, or emotional distress. This article reviews the use of sleep therapies in ASD, among which melatonin has shown promise because of its lack ofsignificant side effects. A better understanding of sleep problems in the etiology of ASD, their impact on the symptoms and behavior of ASD individuals, and their potential use as a secondary aid for treating ASD would represent a significant contribution todevelop strategies to manage the disorder. |
description |
Fil: Karthikeyan, Ramanujam. School of Biological Sciences. Department of Animal Behavior & Physiology; India |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
acceptedVersion |
dc.identifier.none.fl_str_mv |
https://repositorio.uca.edu.ar/handle/123456789/13666 0020-7454 1543-5245 (online) 10.1080/00207454.2019.1711377 Karthikeyan, R., Cardinali, D. P., Shakunthala, V., Spence, D. W., Brown, G.M., Pandi Perumal, S. R. Understanding the role of sleep and its disturbances in autism spectrum disorder [en línea]. Postprint del artículo publicado en: International Journal of Neuroscience. 2020, 130 (10). doi: 10.1080/00207454.2019.1711377. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13666 |
url |
https://repositorio.uca.edu.ar/handle/123456789/13666 |
identifier_str_mv |
0020-7454 1543-5245 (online) 10.1080/00207454.2019.1711377 Karthikeyan, R., Cardinali, D. P., Shakunthala, V., Spence, D. W., Brown, G.M., Pandi Perumal, S. R. Understanding the role of sleep and its disturbances in autism spectrum disorder [en línea]. Postprint del artículo publicado en: International Journal of Neuroscience. 2020, 130 (10). doi: 10.1080/00207454.2019.1711377. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/13666 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Taylor & Francis |
publisher.none.fl_str_mv |
Taylor & Francis |
dc.source.none.fl_str_mv |
International Journal of Neuroscience Vol. 130, No.10.2020 reponame:Repositorio Institucional (UCA) instname:Pontificia Universidad Católica Argentina |
reponame_str |
Repositorio Institucional (UCA) |
collection |
Repositorio Institucional (UCA) |
instname_str |
Pontificia Universidad Católica Argentina |
repository.name.fl_str_mv |
Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina |
repository.mail.fl_str_mv |
claudia_fernandez@uca.edu.ar |
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1836638361007161344 |
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13.13397 |