Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions

Autores
Santos, María V.; Sansiñena, Marina Julia; Chirife, Jorge; Zaritzky, Noemí
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
Fil: Santos, María V. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; Argentina
Fil: Santos, María V. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Santos, María V. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sansiñena, Marina. Pontificia Universidad Católica Argentina. bFacultad de Ingeniería y Ciencias Agrarias; Argentina
Fil: Sansiñena, Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chirife, Jorge. Pontificia Universidad Católica Argentina. Facultad de Ingeniería y Ciencias Agrarias; Argentina
Fil: Zaritzky, Noemí. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; Argentina
Fil: Zaritzky, Noemí. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Zaritzky, Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Abstract: The warming of cryopreserved samples supported by small volume devices is governed by heat transfer phenomena which are mathematically described by the solution of the transient heat conduction partial differential equations; the convective heat transfer coefficient (h) is an important parameter involved in the boundary condition which is related to the fluid dynamic behavior at the interface device-warming fluid (water, sucrose solution or air). Unfortunately, h values for small volume devices (i.e. Cryotop®) have not been experimentally determined. Moreover, heat transfer coefficients during warming of Cryotop® cannot be obtained through classical dimensionless correlations expressed in terms of Nusselt vs. Reynolds and Prandtl numbers that are available for regular geometries and single materials. It is the purpose of present work to determine the convective heat transfer coefficients (h) by numerically solving the heat transfer equation applying the finite element method. Numerical simulations allowed to predict time-temperature histories and warming rates under different protocols in Cryotop® system which were compared with literature warming rates reported for this device. The h values were calculated considering the heterogeneous structure of the domain (microdrop, plastic-support) and the irregular three-dimensional geometry. The warming conditions analyzed were: a) open system in contact with air and sucrose solution at 23 °C) and b) closed system in contact with air and water at 23 °C. The h values of the Cryotop® open system immersed in sucrose solution (23 °C), that according to literature achieved a survival in the order of 80%, are in the range of 1800–2200 W/m2K. The h values obtained in this work for warming conditions are critical parameters for cryobiologists when studying heat transfer rate in this small volume device.
Fuente
Postprint del artículo publicado en Cryobiology, 84, 2018
Materia
CONVECCION DEL CALOR
TRANSFERENCIA DE CALOR
CRIOPRESERVACION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/8310
Acceder
id RIUCA_3c3d5ec5fdddc20e640bddec1ff0d4ed
oai_identifier_str oai:ucacris:123456789/8310
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditionsSantos, María V.Sansiñena, Marina JuliaChirife, JorgeZaritzky, NoemíCONVECCION DEL CALORTRANSFERENCIA DE CALORCRIOPRESERVACIONFil: Santos, María V. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; ArgentinaFil: Santos, María V. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Santos, María V. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sansiñena, Marina. Pontificia Universidad Católica Argentina. bFacultad de Ingeniería y Ciencias Agrarias; ArgentinaFil: Sansiñena, Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Chirife, Jorge. Pontificia Universidad Católica Argentina. Facultad de Ingeniería y Ciencias Agrarias; ArgentinaFil: Zaritzky, Noemí. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; ArgentinaFil: Zaritzky, Noemí. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Zaritzky, Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaAbstract: The warming of cryopreserved samples supported by small volume devices is governed by heat transfer phenomena which are mathematically described by the solution of the transient heat conduction partial differential equations; the convective heat transfer coefficient (h) is an important parameter involved in the boundary condition which is related to the fluid dynamic behavior at the interface device-warming fluid (water, sucrose solution or air). Unfortunately, h values for small volume devices (i.e. Cryotop®) have not been experimentally determined. Moreover, heat transfer coefficients during warming of Cryotop® cannot be obtained through classical dimensionless correlations expressed in terms of Nusselt vs. Reynolds and Prandtl numbers that are available for regular geometries and single materials. It is the purpose of present work to determine the convective heat transfer coefficients (h) by numerically solving the heat transfer equation applying the finite element method. Numerical simulations allowed to predict time-temperature histories and warming rates under different protocols in Cryotop® system which were compared with literature warming rates reported for this device. The h values were calculated considering the heterogeneous structure of the domain (microdrop, plastic-support) and the irregular three-dimensional geometry. The warming conditions analyzed were: a) open system in contact with air and sucrose solution at 23 °C) and b) closed system in contact with air and water at 23 °C. The h values of the Cryotop® open system immersed in sucrose solution (23 °C), that according to literature achieved a survival in the order of 80%, are in the range of 1800–2200 W/m2K. The h values obtained in this work for warming conditions are critical parameters for cryobiologists when studying heat transfer rate in this small volume device.Elsevier2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/83100011-2240 (online)1090-2392 (impreso)10.1016/j.cryobiol.2018.08.007Santos MV, Sansiñena M, Chirife J y Noemí Zaritzky. 2018. Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions [en línea]. Cryobiology, 84. doi: 10.1016/j.cryobiol.2018.08.007 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8310Postprint del artículo publicado en Cryobiology, 84, 2018reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/2025-07-03T10:56:46Zoai:ucacris:123456789/8310instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:56:47.189Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
title Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
spellingShingle Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
Santos, María V.
CONVECCION DEL CALOR
TRANSFERENCIA DE CALOR
CRIOPRESERVACION
title_short Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
title_full Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
title_fullStr Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
title_full_unstemmed Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
title_sort Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions
dc.creator.none.fl_str_mv Santos, María V.
Sansiñena, Marina Julia
Chirife, Jorge
Zaritzky, Noemí
author Santos, María V.
author_facet Santos, María V.
Sansiñena, Marina Julia
Chirife, Jorge
Zaritzky, Noemí
author_role author
author2 Sansiñena, Marina Julia
Chirife, Jorge
Zaritzky, Noemí
author2_role author
author
author
dc.subject.none.fl_str_mv CONVECCION DEL CALOR
TRANSFERENCIA DE CALOR
CRIOPRESERVACION
topic CONVECCION DEL CALOR
TRANSFERENCIA DE CALOR
CRIOPRESERVACION
dc.description.none.fl_txt_mv Fil: Santos, María V. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; Argentina
Fil: Santos, María V. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Santos, María V. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sansiñena, Marina. Pontificia Universidad Católica Argentina. bFacultad de Ingeniería y Ciencias Agrarias; Argentina
Fil: Sansiñena, Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Chirife, Jorge. Pontificia Universidad Católica Argentina. Facultad de Ingeniería y Ciencias Agrarias; Argentina
Fil: Zaritzky, Noemí. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; Argentina
Fil: Zaritzky, Noemí. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Zaritzky, Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Abstract: The warming of cryopreserved samples supported by small volume devices is governed by heat transfer phenomena which are mathematically described by the solution of the transient heat conduction partial differential equations; the convective heat transfer coefficient (h) is an important parameter involved in the boundary condition which is related to the fluid dynamic behavior at the interface device-warming fluid (water, sucrose solution or air). Unfortunately, h values for small volume devices (i.e. Cryotop®) have not been experimentally determined. Moreover, heat transfer coefficients during warming of Cryotop® cannot be obtained through classical dimensionless correlations expressed in terms of Nusselt vs. Reynolds and Prandtl numbers that are available for regular geometries and single materials. It is the purpose of present work to determine the convective heat transfer coefficients (h) by numerically solving the heat transfer equation applying the finite element method. Numerical simulations allowed to predict time-temperature histories and warming rates under different protocols in Cryotop® system which were compared with literature warming rates reported for this device. The h values were calculated considering the heterogeneous structure of the domain (microdrop, plastic-support) and the irregular three-dimensional geometry. The warming conditions analyzed were: a) open system in contact with air and sucrose solution at 23 °C) and b) closed system in contact with air and water at 23 °C. The h values of the Cryotop® open system immersed in sucrose solution (23 °C), that according to literature achieved a survival in the order of 80%, are in the range of 1800–2200 W/m2K. The h values obtained in this work for warming conditions are critical parameters for cryobiologists when studying heat transfer rate in this small volume device.
description Fil: Santos, María V. Universidad Nacional de La Plata. Facultad de Ingeniería. Departamente de Ingeniería Química; Argentina
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/8310
0011-2240 (online)
1090-2392 (impreso)
10.1016/j.cryobiol.2018.08.007
Santos MV, Sansiñena M, Chirife J y Noemí Zaritzky. 2018. Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions [en línea]. Cryobiology, 84. doi: 10.1016/j.cryobiol.2018.08.007 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8310
url https://repositorio.uca.edu.ar/handle/123456789/8310
identifier_str_mv 0011-2240 (online)
1090-2392 (impreso)
10.1016/j.cryobiol.2018.08.007
Santos MV, Sansiñena M, Chirife J y Noemí Zaritzky. 2018. Convective heat transfer coefficients of open and closed Cryotop® systems under different warming conditions [en línea]. Cryobiology, 84. doi: 10.1016/j.cryobiol.2018.08.007 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/8310
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Postprint del artículo publicado en Cryobiology, 84, 2018
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 13.070432

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