Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis

Autores
Martín, Andrea P.; Vieira de Moraes, Luciana; Tadokoro, Carlos E.; Commodaro, Alessandra G.; Urrets Zavalía, Enrique Alberto; Rabinovich, Gabriel A.; Urrets Zavalía, Julio; Rizzo, Lucio V.; Serra, Horacio M.
Año de publicación
2005
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión aceptada
Descripción
Recruitment of lymphocytes into the retina and to the vitreous during the development of experimental autoimmune uveitis (EAU) is governed by factors such as the state of activation of inflammatory cells and the repertoire of adhesion molecules expressed by the local vascular endothelia. alpha4 Integrins and their receptors play an important role during homing of cells to the inflammatory site. In the present study, the effect of alpha4-integrin inhibitor on the development of EAU was investigated.
Fil: Martín, Andrea P. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Vieira de Moraes, Luciana. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Tadokoro, Carlos E. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Commodaro, Alessandra G. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Urrets Zavalía, Enrique Alberto. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Rabinovich, Gabriel A. Hospital de Clínicas “José de San Martín"; Argentina
Fil: Urrets Zavalía, Julio. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Rizzo, Lucio V. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Serra, Horacio M. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fuente
Martín, Andrea P., Vieira de Moraes, Luciana, Tadokoro, Carlos E., Commodaro, Alessandra G., Urrets Zavalía, Enrique Alberto, Rabinovich, Gabriel A., Urrets Zavalía, Julio ORCID: https://orcid.org/0000-0003-2267-2783 , Rizzo, Lucio V. and Serra, Horacio M. ORCID: https://orcid.org/0000-0003-4979-8642 (2005) Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis. Investigative Ophthalmology & Visual Science, 46 (6). pp. 2056-2063. ISSN 0146-0404
Materia
RE Oftalmología
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/4.0/deed.es
Repositorio
Producción Académica (UCC)
Institución
Universidad Católica de Córdoba
OAI Identificador
oai:pa.bibdigital.uccor.edu.ar:4272
Acceder
id PAUCC_49d01fe9e74ced72d39ec6c87943ae2e
oai_identifier_str oai:pa.bibdigital.uccor.edu.ar:4272
network_acronym_str PAUCC
repository_id_str 2718
network_name_str Producción Académica (UCC)
spelling Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune UveitisMartín, Andrea P.Vieira de Moraes, LucianaTadokoro, Carlos E.Commodaro, Alessandra G.Urrets Zavalía, Enrique AlbertoRabinovich, Gabriel A.Urrets Zavalía, JulioRizzo, Lucio V.Serra, Horacio M.RE OftalmologíaRecruitment of lymphocytes into the retina and to the vitreous during the development of experimental autoimmune uveitis (EAU) is governed by factors such as the state of activation of inflammatory cells and the repertoire of adhesion molecules expressed by the local vascular endothelia. alpha4 Integrins and their receptors play an important role during homing of cells to the inflammatory site. In the present study, the effect of alpha4-integrin inhibitor on the development of EAU was investigated.Fil: Martín, Andrea P. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, BrazilFil: Vieira de Moraes, Luciana. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, BrazilFil: Tadokoro, Carlos E. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, BrazilFil: Commodaro, Alessandra G. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, BrazilFil: Urrets Zavalía, Enrique Alberto. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Rabinovich, Gabriel A. Hospital de Clínicas “José de San Martín"; ArgentinaFil: Urrets Zavalía, Julio. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; ArgentinaFil: Rizzo, Lucio V. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, BrazilFil: Serra, Horacio M. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaAssociation for Research in Vision and Ophthalmology2005-06-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://pa.bibdigital.ucc.edu.ar/4272/1/A_Martin_Vieira_R.pdf Martín, Andrea P., Vieira de Moraes, Luciana, Tadokoro, Carlos E., Commodaro, Alessandra G., Urrets Zavalía, Enrique Alberto, Rabinovich, Gabriel A., Urrets Zavalía, Julio ORCID: https://orcid.org/0000-0003-2267-2783 <https://orcid.org/0000-0003-2267-2783>, Rizzo, Lucio V. and Serra, Horacio M. ORCID: https://orcid.org/0000-0003-4979-8642 <https://orcid.org/0000-0003-4979-8642> (2005) Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis. Investigative Ophthalmology & Visual Science, 46 (6). pp. 2056-2063. ISSN 0146-0404 reponame:Producción Académica (UCC)instname:Universidad Católica de Córdobaspahttp://pa.bibdigital.ucc.edu.ar/4272/https://ri.conicet.gov.ar/handle/11336/31474info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/4.0/deed.es2025-10-16T10:06:38Zoai:pa.bibdigital.uccor.edu.ar:4272instacron:UCCInstitucionalhttp://pa.bibdigital.uccor.edu.ar/Universidad privadaNo correspondehttp://pa.bibdigital.uccor.edu.ar/cgi/oai2bibdir@uccor.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:27182025-10-16 10:06:38.185Producción Académica (UCC) - Universidad Católica de Córdobafalse
dc.title.none.fl_str_mv Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
title Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
spellingShingle Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
Martín, Andrea P.
RE Oftalmología
title_short Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
title_full Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
title_fullStr Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
title_full_unstemmed Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
title_sort Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis
dc.creator.none.fl_str_mv Martín, Andrea P.
Vieira de Moraes, Luciana
Tadokoro, Carlos E.
Commodaro, Alessandra G.
Urrets Zavalía, Enrique Alberto
Rabinovich, Gabriel A.
Urrets Zavalía, Julio
Rizzo, Lucio V.
Serra, Horacio M.
author Martín, Andrea P.
author_facet Martín, Andrea P.
Vieira de Moraes, Luciana
Tadokoro, Carlos E.
Commodaro, Alessandra G.
Urrets Zavalía, Enrique Alberto
Rabinovich, Gabriel A.
Urrets Zavalía, Julio
Rizzo, Lucio V.
Serra, Horacio M.
author_role author
author2 Vieira de Moraes, Luciana
Tadokoro, Carlos E.
Commodaro, Alessandra G.
Urrets Zavalía, Enrique Alberto
Rabinovich, Gabriel A.
Urrets Zavalía, Julio
Rizzo, Lucio V.
Serra, Horacio M.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv RE Oftalmología
topic RE Oftalmología
dc.description.none.fl_txt_mv Recruitment of lymphocytes into the retina and to the vitreous during the development of experimental autoimmune uveitis (EAU) is governed by factors such as the state of activation of inflammatory cells and the repertoire of adhesion molecules expressed by the local vascular endothelia. alpha4 Integrins and their receptors play an important role during homing of cells to the inflammatory site. In the present study, the effect of alpha4-integrin inhibitor on the development of EAU was investigated.
Fil: Martín, Andrea P. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Vieira de Moraes, Luciana. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Tadokoro, Carlos E. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Commodaro, Alessandra G. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Urrets Zavalía, Enrique Alberto. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Rabinovich, Gabriel A. Hospital de Clínicas “José de San Martín"; Argentina
Fil: Urrets Zavalía, Julio. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
Fil: Rizzo, Lucio V. Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
Fil: Serra, Horacio M. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
description Recruitment of lymphocytes into the retina and to the vitreous during the development of experimental autoimmune uveitis (EAU) is governed by factors such as the state of activation of inflammatory cells and the repertoire of adhesion molecules expressed by the local vascular endothelia. alpha4 Integrins and their receptors play an important role during homing of cells to the inflammatory site. In the present study, the effect of alpha4-integrin inhibitor on the development of EAU was investigated.
publishDate 2005
dc.date.none.fl_str_mv 2005-06-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://pa.bibdigital.ucc.edu.ar/4272/1/A_Martin_Vieira_R.pdf
url http://pa.bibdigital.ucc.edu.ar/4272/1/A_Martin_Vieira_R.pdf
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://pa.bibdigital.ucc.edu.ar/4272/
https://ri.conicet.gov.ar/handle/11336/31474
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/deed.es
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/deed.es
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Association for Research in Vision and Ophthalmology
publisher.none.fl_str_mv Association for Research in Vision and Ophthalmology
dc.source.none.fl_str_mv Martín, Andrea P., Vieira de Moraes, Luciana, Tadokoro, Carlos E., Commodaro, Alessandra G., Urrets Zavalía, Enrique Alberto, Rabinovich, Gabriel A., Urrets Zavalía, Julio ORCID: https://orcid.org/0000-0003-2267-2783 <https://orcid.org/0000-0003-2267-2783>, Rizzo, Lucio V. and Serra, Horacio M. ORCID: https://orcid.org/0000-0003-4979-8642 <https://orcid.org/0000-0003-4979-8642> (2005) Administration of a Peptide Inhibitor of α4-Integrin Inhibits the Development of Experimental Autoimmune Uveitis. Investigative Ophthalmology & Visual Science, 46 (6). pp. 2056-2063. ISSN 0146-0404
reponame:Producción Académica (UCC)
instname:Universidad Católica de Córdoba
reponame_str Producción Académica (UCC)
collection Producción Académica (UCC)
instname_str Universidad Católica de Córdoba
repository.name.fl_str_mv Producción Académica (UCC) - Universidad Católica de Córdoba
repository.mail.fl_str_mv bibdir@uccor.edu.ar
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score 12.712165

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