IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials

Autores
Leiva, Carlos; Gallardo, Mauro Julián; Casanova, Natalia Andrea; Terzolo, Horacio; Chacana, Pablo
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products. This review provides a comprehensive analysis of IgY-based biologicals for human medicine, including patent applications and clinical trials during the period 2010–2018, and addresses how IgY-technology can lead to innovation in the production of biologicals for the treatment and prophylaxis of a wide range of infectious and non-communicable diseases.
Instituto de Patobiología
Fil: Leiva, Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gallardo, Mauro Julián. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Casanova, Natalia Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Terzolo, Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina
Fil: Chacana, Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fuente
International Immunopharmacology 81 : 106269 (Abril 2020)
Materia
Antibodies
Egg Yolk
Therapy
Patents
Clinical Trials
Medical Sciences
Human Diseases
Anticuerpos
Yema de Huevo
Terapia
Patentes
Ensayos Clínicos
Ciencias Médicas
Enfermedades Humanas
IgY Antibody
Anticuerpo IgY
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/6713
Acceder
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spelling IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trialsLeiva, CarlosGallardo, Mauro JuliánCasanova, Natalia AndreaTerzolo, HoracioChacana, PabloAntibodiesEgg YolkTherapyPatentsClinical TrialsMedical SciencesHuman DiseasesAnticuerposYema de HuevoTerapiaPatentesEnsayos ClínicosCiencias MédicasEnfermedades HumanasIgY AntibodyAnticuerpo IgYIgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products. This review provides a comprehensive analysis of IgY-based biologicals for human medicine, including patent applications and clinical trials during the period 2010–2018, and addresses how IgY-technology can lead to innovation in the production of biologicals for the treatment and prophylaxis of a wide range of infectious and non-communicable diseases.Instituto de PatobiologíaFil: Leiva, Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gallardo, Mauro Julián. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Casanova, Natalia Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Terzolo, Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; ArgentinaFil: Chacana, Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2020-02-11T11:10:19Z2020-02-11T11:10:19Z2020-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/6713https://www.sciencedirect.com/science/article/pii/S15675769193236771567-5769https://doi.org/10.1016/j.intimp.2020.106269International Immunopharmacology 81 : 106269 (Abril 2020)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-10-16T09:29:44Zoai:localhost:20.500.12123/6713instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-16 09:29:45.126INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
title IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
spellingShingle IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
Leiva, Carlos
Antibodies
Egg Yolk
Therapy
Patents
Clinical Trials
Medical Sciences
Human Diseases
Anticuerpos
Yema de Huevo
Terapia
Patentes
Ensayos Clínicos
Ciencias Médicas
Enfermedades Humanas
IgY Antibody
Anticuerpo IgY
title_short IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
title_full IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
title_fullStr IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
title_full_unstemmed IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
title_sort IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
dc.creator.none.fl_str_mv Leiva, Carlos
Gallardo, Mauro Julián
Casanova, Natalia Andrea
Terzolo, Horacio
Chacana, Pablo
author Leiva, Carlos
author_facet Leiva, Carlos
Gallardo, Mauro Julián
Casanova, Natalia Andrea
Terzolo, Horacio
Chacana, Pablo
author_role author
author2 Gallardo, Mauro Julián
Casanova, Natalia Andrea
Terzolo, Horacio
Chacana, Pablo
author2_role author
author
author
author
dc.subject.none.fl_str_mv Antibodies
Egg Yolk
Therapy
Patents
Clinical Trials
Medical Sciences
Human Diseases
Anticuerpos
Yema de Huevo
Terapia
Patentes
Ensayos Clínicos
Ciencias Médicas
Enfermedades Humanas
IgY Antibody
Anticuerpo IgY
topic Antibodies
Egg Yolk
Therapy
Patents
Clinical Trials
Medical Sciences
Human Diseases
Anticuerpos
Yema de Huevo
Terapia
Patentes
Ensayos Clínicos
Ciencias Médicas
Enfermedades Humanas
IgY Antibody
Anticuerpo IgY
dc.description.none.fl_txt_mv IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products. This review provides a comprehensive analysis of IgY-based biologicals for human medicine, including patent applications and clinical trials during the period 2010–2018, and addresses how IgY-technology can lead to innovation in the production of biologicals for the treatment and prophylaxis of a wide range of infectious and non-communicable diseases.
Instituto de Patobiología
Fil: Leiva, Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gallardo, Mauro Julián. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Casanova, Natalia Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Terzolo, Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina
Fil: Chacana, Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products. This review provides a comprehensive analysis of IgY-based biologicals for human medicine, including patent applications and clinical trials during the period 2010–2018, and addresses how IgY-technology can lead to innovation in the production of biologicals for the treatment and prophylaxis of a wide range of infectious and non-communicable diseases.
publishDate 2020
dc.date.none.fl_str_mv 2020-02-11T11:10:19Z
2020-02-11T11:10:19Z
2020-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/6713
https://www.sciencedirect.com/science/article/pii/S1567576919323677
1567-5769
https://doi.org/10.1016/j.intimp.2020.106269
url http://hdl.handle.net/20.500.12123/6713
https://www.sciencedirect.com/science/article/pii/S1567576919323677
https://doi.org/10.1016/j.intimp.2020.106269
identifier_str_mv 1567-5769
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv International Immunopharmacology 81 : 106269 (Abril 2020)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.712165

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