HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina

Autores
Margineda, Carlos Augusto; Ferreyra, Franco Matías; Masnyj, Franco Ezequiel; Audrito, Maximiliano; Favaro, Paula Melisa; Dus Santos, Maria Jose; Pecora, Andrea
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
HoBi-like pestivirus (HoBiPeV) is an emerging virus that has been detected in cattle and other ruminants. We diagnosed 2 cases of fatal bovine respiratory disease complex (BRDC) associated with infection with HoBiPeV in a feedlot in Argentina. The main findings in 2 steers autopsied were interstitial bronchopneumonia (case 1) and fibrinous bronchopneumonia (case 2). HoBiPeV was detected by RT-PCR in lungs of both animals and by immunohistochemistry in case 2. Phylogenetic analysis showed that both strains clustered within the “Brazilian-Italian” clade. In case 2, Mannheimia haemolytica was isolated from the lung. There is scant information about the contribution of HoBiPeV to the pathogenesis of BRDC. To our knowledge, HoBiPeV has not been reported previously in association with M. haemolytica pneumonia. Our findings further support the involvement of HoBiPeV in cases of BRDC and contribute to understanding the synergy of this etiologic agent in the pathogenesis of BRD, which is critical for the development of appropriate preventive strategies.
EEA Marcos Juárez
Fil: Margineda, Carlos Augusto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina.
Fil: Margineda, Carlos Augusto. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina
Fil: Ferreyra, Franco Matías. Kansas State University. Veterinary Diagnostic Laboratory; Estados Unidos
Fil: Masnyj, Franco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina.
Fil: Audrito, Maximiliano. Establecimiento Don Sebastián, Córdoba; Argentina
Fil: Favaro, Paula Melisa. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina
Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas; Argentina
Fil: Dus Santos, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pecora, Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas; Argentina
Fil: Pecora, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fuente
Journal of Veterinary Diagnostic Investigation 34 (4) : 693-698 (July 2022)
Materia
Pestivirus
Animal Diseases
Cattle
Respiratory Diseases
Bovine Diarrhoea Pestivirus
Enfermedades de los Animales
Ganado Bovino
Enfermedades Respiratorias
Pestivirus de la Diarrea Bovina
Argentina
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/12745
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oai_identifier_str oai:localhost:20.500.12123/12745
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network_name_str INTA Digital (INTA)
spelling HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in ArgentinaMargineda, Carlos AugustoFerreyra, Franco MatíasMasnyj, Franco EzequielAudrito, MaximilianoFavaro, Paula MelisaDus Santos, Maria JosePecora, AndreaPestivirusAnimal DiseasesCattleRespiratory DiseasesBovine Diarrhoea PestivirusEnfermedades de los AnimalesGanado BovinoEnfermedades RespiratoriasPestivirus de la Diarrea BovinaArgentinaHoBi-like pestivirus (HoBiPeV) is an emerging virus that has been detected in cattle and other ruminants. We diagnosed 2 cases of fatal bovine respiratory disease complex (BRDC) associated with infection with HoBiPeV in a feedlot in Argentina. The main findings in 2 steers autopsied were interstitial bronchopneumonia (case 1) and fibrinous bronchopneumonia (case 2). HoBiPeV was detected by RT-PCR in lungs of both animals and by immunohistochemistry in case 2. Phylogenetic analysis showed that both strains clustered within the “Brazilian-Italian” clade. In case 2, Mannheimia haemolytica was isolated from the lung. There is scant information about the contribution of HoBiPeV to the pathogenesis of BRDC. To our knowledge, HoBiPeV has not been reported previously in association with M. haemolytica pneumonia. Our findings further support the involvement of HoBiPeV in cases of BRDC and contribute to understanding the synergy of this etiologic agent in the pathogenesis of BRD, which is critical for the development of appropriate preventive strategies.EEA Marcos JuárezFil: Margineda, Carlos Augusto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina.Fil: Margineda, Carlos Augusto. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; ArgentinaFil: Ferreyra, Franco Matías. Kansas State University. Veterinary Diagnostic Laboratory; Estados UnidosFil: Masnyj, Franco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina.Fil: Audrito, Maximiliano. Establecimiento Don Sebastián, Córdoba; ArgentinaFil: Favaro, Paula Melisa. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; ArgentinaFil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas; ArgentinaFil: Dus Santos, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pecora, Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas; ArgentinaFil: Pecora, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaAmerican Association of Veterinary Laboratory Diagnosticians2022-08-31T16:52:44Z2022-08-31T16:52:44Z2022-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/12745https://journals.sagepub.com/doi/10.1177/104063872210983561040-63871943-4936https://doi.org/10.1177/10406387221098356Journal of Veterinary Diagnostic Investigation 34 (4) : 693-698 (July 2022)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/PNSA-1115054/AR./Enfermedades parasitarias, infecciosas y tóxico metabólicas que afectan la productividad de los bóvidos para producción de carne y leche.info:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001/2019-RIST-E5-I111-001/AR./Laboratorios de Diagnóstico Veterinarioinfo:eu-repograntAgreement/INTA/2019-PD-E5-I103-001/2019-PD-E5-I103-001/AR./Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud públicaArgentina .......... (nation) (World, South America)7006477info:eu-repo/semantics/restrictedAccess2025-09-04T09:49:33Zoai:localhost:20.500.12123/12745instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:49:33.571INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
title HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
spellingShingle HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
Margineda, Carlos Augusto
Pestivirus
Animal Diseases
Cattle
Respiratory Diseases
Bovine Diarrhoea Pestivirus
Enfermedades de los Animales
Ganado Bovino
Enfermedades Respiratorias
Pestivirus de la Diarrea Bovina
Argentina
title_short HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
title_full HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
title_fullStr HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
title_full_unstemmed HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
title_sort HoBi-like pestivirus in 2 cases of fatal respiratory disease of feedlot cattle in Argentina
dc.creator.none.fl_str_mv Margineda, Carlos Augusto
Ferreyra, Franco Matías
Masnyj, Franco Ezequiel
Audrito, Maximiliano
Favaro, Paula Melisa
Dus Santos, Maria Jose
Pecora, Andrea
author Margineda, Carlos Augusto
author_facet Margineda, Carlos Augusto
Ferreyra, Franco Matías
Masnyj, Franco Ezequiel
Audrito, Maximiliano
Favaro, Paula Melisa
Dus Santos, Maria Jose
Pecora, Andrea
author_role author
author2 Ferreyra, Franco Matías
Masnyj, Franco Ezequiel
Audrito, Maximiliano
Favaro, Paula Melisa
Dus Santos, Maria Jose
Pecora, Andrea
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Pestivirus
Animal Diseases
Cattle
Respiratory Diseases
Bovine Diarrhoea Pestivirus
Enfermedades de los Animales
Ganado Bovino
Enfermedades Respiratorias
Pestivirus de la Diarrea Bovina
Argentina
topic Pestivirus
Animal Diseases
Cattle
Respiratory Diseases
Bovine Diarrhoea Pestivirus
Enfermedades de los Animales
Ganado Bovino
Enfermedades Respiratorias
Pestivirus de la Diarrea Bovina
Argentina
dc.description.none.fl_txt_mv HoBi-like pestivirus (HoBiPeV) is an emerging virus that has been detected in cattle and other ruminants. We diagnosed 2 cases of fatal bovine respiratory disease complex (BRDC) associated with infection with HoBiPeV in a feedlot in Argentina. The main findings in 2 steers autopsied were interstitial bronchopneumonia (case 1) and fibrinous bronchopneumonia (case 2). HoBiPeV was detected by RT-PCR in lungs of both animals and by immunohistochemistry in case 2. Phylogenetic analysis showed that both strains clustered within the “Brazilian-Italian” clade. In case 2, Mannheimia haemolytica was isolated from the lung. There is scant information about the contribution of HoBiPeV to the pathogenesis of BRDC. To our knowledge, HoBiPeV has not been reported previously in association with M. haemolytica pneumonia. Our findings further support the involvement of HoBiPeV in cases of BRDC and contribute to understanding the synergy of this etiologic agent in the pathogenesis of BRD, which is critical for the development of appropriate preventive strategies.
EEA Marcos Juárez
Fil: Margineda, Carlos Augusto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina.
Fil: Margineda, Carlos Augusto. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina
Fil: Ferreyra, Franco Matías. Kansas State University. Veterinary Diagnostic Laboratory; Estados Unidos
Fil: Masnyj, Franco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Marcos Juárez; Argentina.
Fil: Audrito, Maximiliano. Establecimiento Don Sebastián, Córdoba; Argentina
Fil: Favaro, Paula Melisa. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina
Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas; Argentina
Fil: Dus Santos, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pecora, Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas; Argentina
Fil: Pecora, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description HoBi-like pestivirus (HoBiPeV) is an emerging virus that has been detected in cattle and other ruminants. We diagnosed 2 cases of fatal bovine respiratory disease complex (BRDC) associated with infection with HoBiPeV in a feedlot in Argentina. The main findings in 2 steers autopsied were interstitial bronchopneumonia (case 1) and fibrinous bronchopneumonia (case 2). HoBiPeV was detected by RT-PCR in lungs of both animals and by immunohistochemistry in case 2. Phylogenetic analysis showed that both strains clustered within the “Brazilian-Italian” clade. In case 2, Mannheimia haemolytica was isolated from the lung. There is scant information about the contribution of HoBiPeV to the pathogenesis of BRDC. To our knowledge, HoBiPeV has not been reported previously in association with M. haemolytica pneumonia. Our findings further support the involvement of HoBiPeV in cases of BRDC and contribute to understanding the synergy of this etiologic agent in the pathogenesis of BRD, which is critical for the development of appropriate preventive strategies.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-31T16:52:44Z
2022-08-31T16:52:44Z
2022-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/12745
https://journals.sagepub.com/doi/10.1177/10406387221098356
1040-6387
1943-4936
https://doi.org/10.1177/10406387221098356
url http://hdl.handle.net/20.500.12123/12745
https://journals.sagepub.com/doi/10.1177/10406387221098356
https://doi.org/10.1177/10406387221098356
identifier_str_mv 1040-6387
1943-4936
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/PNSA-1115054/AR./Enfermedades parasitarias, infecciosas y tóxico metabólicas que afectan la productividad de los bóvidos para producción de carne y leche.
info:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001/2019-RIST-E5-I111-001/AR./Laboratorios de Diagnóstico Veterinario
info:eu-repograntAgreement/INTA/2019-PD-E5-I103-001/2019-PD-E5-I103-001/AR./Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud pública
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Argentina .......... (nation) (World, South America)
7006477
dc.publisher.none.fl_str_mv American Association of Veterinary Laboratory Diagnosticians
publisher.none.fl_str_mv American Association of Veterinary Laboratory Diagnosticians
dc.source.none.fl_str_mv Journal of Veterinary Diagnostic Investigation 34 (4) : 693-698 (July 2022)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.623145

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