Vaccination against δ-retroviruses : the bovine leukemia virus paradigm

Autores
Gutierrez, Gerónimo; Rodriguez, Sabrina M.; de Brogniez, Alix; Gillet, Nicolas A.; Golime, Ramarao; Burny, Arsene; Jaworski, Juan Pablo; Alvarez, Irene; Vagnoni, Lucas Emilio; Trono, Karina Gabriela; Willems, Luc
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Bovine leukemia virus (BLV) and human T-lymphotropic virus type 1 (HTLV-1) are closely related d-retroviruses that induce hematological diseases. HTLV-1 infects about 15 million people worldwide, mainly in subtropical areas. HTLV-1 induces a wide spectrum of diseases (e.g., HTLV-associated myelopathy/tropical spastic paraparesis) and leukemia/lymphoma (adult T-cell leukemia). Bovine leukemia virus is a major pathogen of cattle, causing important economic losses due to a reduction in production, export limitations and lymphoma-associated death. In the absence of satisfactory treatment for these diseases and besides the prevention of transmission, the best option to reduce the prevalence of d-retroviruses is vaccination. Here, we provide an overview of the different vaccination strategies in the BLV model and outline key parameters required for vaccine efficacy.
Instituto de Virología
Fil: Gutierrez, Gerónimo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Rodriguez, Sabrina M. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: de Brogniez, Alix. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Gillet, Nicolas. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Golime, Romarao. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Burny, Arsene. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Jaworski, Juan Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Alvarez, Irene. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Vagnoni, Lucas Emilio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Trono, Karina Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Willems, Luc. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fuente
Viruses 6 (6) : 2416-2427. (Junio 2014)
Materia
Bovine Leukaemia Virus
Retroviridae
Vaccination
Antibodies
Virus Leucemia Bovina
Vacunación
Anticuerpos
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/3586
Acceder
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oai_identifier_str oai:localhost:20.500.12123/3586
network_acronym_str INTADig
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network_name_str INTA Digital (INTA)
spelling Vaccination against δ-retroviruses : the bovine leukemia virus paradigmGutierrez, GerónimoRodriguez, Sabrina M.de Brogniez, AlixGillet, Nicolas A.Golime, RamaraoBurny, ArseneJaworski, Juan PabloAlvarez, IreneVagnoni, Lucas EmilioTrono, Karina GabrielaWillems, LucBovine Leukaemia VirusRetroviridaeVaccinationAntibodiesVirus Leucemia BovinaVacunaciónAnticuerposBovine leukemia virus (BLV) and human T-lymphotropic virus type 1 (HTLV-1) are closely related d-retroviruses that induce hematological diseases. HTLV-1 infects about 15 million people worldwide, mainly in subtropical areas. HTLV-1 induces a wide spectrum of diseases (e.g., HTLV-associated myelopathy/tropical spastic paraparesis) and leukemia/lymphoma (adult T-cell leukemia). Bovine leukemia virus is a major pathogen of cattle, causing important economic losses due to a reduction in production, export limitations and lymphoma-associated death. In the absence of satisfactory treatment for these diseases and besides the prevention of transmission, the best option to reduce the prevalence of d-retroviruses is vaccination. Here, we provide an overview of the different vaccination strategies in the BLV model and outline key parameters required for vaccine efficacy.Instituto de VirologíaFil: Gutierrez, Gerónimo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Rodriguez, Sabrina M. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; BélgicaFil: de Brogniez, Alix. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; BélgicaFil: Gillet, Nicolas. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; BélgicaFil: Golime, Romarao. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; BélgicaFil: Burny, Arsene. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; BélgicaFil: Jaworski, Juan Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Alvarez, Irene. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Vagnoni, Lucas Emilio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Trono, Karina Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Willems, Luc. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica2018-10-12T15:23:07Z2018-10-12T15:23:07Z2014-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://www.mdpi.com/1999-4915/6/6/2416http://hdl.handle.net/20.500.12123/35861999-4915https://doi.org/10.3390/v6062416Viruses 6 (6) : 2416-2427. (Junio 2014)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/PNSA/1115054/AR./Enfermedades parasitarias, infecciosas y tóxico metabólicas que afectan la productividad de los bóvidos para producción de carne y leche.info:eu-repograntAgreement/INTA/PNBIO/1131032/AR./Desarrollo de herramientas biotecnológicas para la prevención y el control de enfermedades pecuarias: vacunas, diagnóstico y eIdemiología molecular.info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-04T09:47:35Zoai:localhost:20.500.12123/3586instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:47:37.142INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
title Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
spellingShingle Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
Gutierrez, Gerónimo
Bovine Leukaemia Virus
Retroviridae
Vaccination
Antibodies
Virus Leucemia Bovina
Vacunación
Anticuerpos
title_short Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
title_full Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
title_fullStr Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
title_full_unstemmed Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
title_sort Vaccination against δ-retroviruses : the bovine leukemia virus paradigm
dc.creator.none.fl_str_mv Gutierrez, Gerónimo
Rodriguez, Sabrina M.
de Brogniez, Alix
Gillet, Nicolas A.
Golime, Ramarao
Burny, Arsene
Jaworski, Juan Pablo
Alvarez, Irene
Vagnoni, Lucas Emilio
Trono, Karina Gabriela
Willems, Luc
author Gutierrez, Gerónimo
author_facet Gutierrez, Gerónimo
Rodriguez, Sabrina M.
de Brogniez, Alix
Gillet, Nicolas A.
Golime, Ramarao
Burny, Arsene
Jaworski, Juan Pablo
Alvarez, Irene
Vagnoni, Lucas Emilio
Trono, Karina Gabriela
Willems, Luc
author_role author
author2 Rodriguez, Sabrina M.
de Brogniez, Alix
Gillet, Nicolas A.
Golime, Ramarao
Burny, Arsene
Jaworski, Juan Pablo
Alvarez, Irene
Vagnoni, Lucas Emilio
Trono, Karina Gabriela
Willems, Luc
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Bovine Leukaemia Virus
Retroviridae
Vaccination
Antibodies
Virus Leucemia Bovina
Vacunación
Anticuerpos
topic Bovine Leukaemia Virus
Retroviridae
Vaccination
Antibodies
Virus Leucemia Bovina
Vacunación
Anticuerpos
dc.description.none.fl_txt_mv Bovine leukemia virus (BLV) and human T-lymphotropic virus type 1 (HTLV-1) are closely related d-retroviruses that induce hematological diseases. HTLV-1 infects about 15 million people worldwide, mainly in subtropical areas. HTLV-1 induces a wide spectrum of diseases (e.g., HTLV-associated myelopathy/tropical spastic paraparesis) and leukemia/lymphoma (adult T-cell leukemia). Bovine leukemia virus is a major pathogen of cattle, causing important economic losses due to a reduction in production, export limitations and lymphoma-associated death. In the absence of satisfactory treatment for these diseases and besides the prevention of transmission, the best option to reduce the prevalence of d-retroviruses is vaccination. Here, we provide an overview of the different vaccination strategies in the BLV model and outline key parameters required for vaccine efficacy.
Instituto de Virología
Fil: Gutierrez, Gerónimo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Rodriguez, Sabrina M. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: de Brogniez, Alix. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Gillet, Nicolas. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Golime, Romarao. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Burny, Arsene. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
Fil: Jaworski, Juan Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Alvarez, Irene. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Vagnoni, Lucas Emilio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Trono, Karina Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Willems, Luc. University of Liège. Molecular and Cellular Epigenetics; Bélgica. University of Liège. Molecular and Cellular Biology, Gembloux Agro-Bio Tech; Bélgica
description Bovine leukemia virus (BLV) and human T-lymphotropic virus type 1 (HTLV-1) are closely related d-retroviruses that induce hematological diseases. HTLV-1 infects about 15 million people worldwide, mainly in subtropical areas. HTLV-1 induces a wide spectrum of diseases (e.g., HTLV-associated myelopathy/tropical spastic paraparesis) and leukemia/lymphoma (adult T-cell leukemia). Bovine leukemia virus is a major pathogen of cattle, causing important economic losses due to a reduction in production, export limitations and lymphoma-associated death. In the absence of satisfactory treatment for these diseases and besides the prevention of transmission, the best option to reduce the prevalence of d-retroviruses is vaccination. Here, we provide an overview of the different vaccination strategies in the BLV model and outline key parameters required for vaccine efficacy.
publishDate 2014
dc.date.none.fl_str_mv 2014-06
2018-10-12T15:23:07Z
2018-10-12T15:23:07Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.mdpi.com/1999-4915/6/6/2416
http://hdl.handle.net/20.500.12123/3586
1999-4915
https://doi.org/10.3390/v6062416
url https://www.mdpi.com/1999-4915/6/6/2416
http://hdl.handle.net/20.500.12123/3586
https://doi.org/10.3390/v6062416
identifier_str_mv 1999-4915
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/PNSA/1115054/AR./Enfermedades parasitarias, infecciosas y tóxico metabólicas que afectan la productividad de los bóvidos para producción de carne y leche.
info:eu-repograntAgreement/INTA/PNBIO/1131032/AR./Desarrollo de herramientas biotecnológicas para la prevención y el control de enfermedades pecuarias: vacunas, diagnóstico y eIdemiología molecular.
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Viruses 6 (6) : 2416-2427. (Junio 2014)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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