Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions

Authors
Aduriz Guerrero, Matí­as; Carossino, Mariano; Go, Y.Y.; Vincke, Cécile; Balasuriya, Udeni B.R.; Muyldermans, S.; Wigdorovitz, Andres; Barrandeguy, Maria Edith; Parreño, Viviana
Publication Year
2016
Language
English
Format
article
Status
Published version
Description
In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions.
Inst.de Virología
Fil: Aduriz Guerrero, Matí­as. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Carossino, Mariano. Universidad del Salvador. Escuela de Veterinaria; Argentina. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos
Fil: Go, Y.Y. Korea Research Institute of Chemical Technology. Division of Drug Discovery Research. Virus Research and Testing Group; Corea
Fil: Vincke, Cécile. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica
Fil: Balasuriya,Udeni B.R. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos
Fil: Muyldermans, Serge. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica
Fil: Wigdorovitz, Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; Argentina
Fil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Source
Journal of equine veterinary science 39 : S56eS65
Subject
Animal Diseases
Stallions
Nanotechnology
Equine Arteritis Virus
Enfermedades de los Animales
Caballos Sementales
Nanotecnología
Virus de la Arteritis Equina
Access level
Open access
Condiciones de uso
Repository
INTA Digital (INTA)
Institution
Instituto Nacional de Tecnología Agropecuaria
OAI Identifier
oai:localhost:20.500.12123/1009