Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions

Autores
Aduriz Guerrero, Matí­as; Carossino, Mariano; Go, Y.Y.; Vincke, Cécile; Balasuriya, Udeni B.R.; Muyldermans, S.; Wigdorovitz, Andres; Barrandeguy, Maria Edith; Parreño, Viviana
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions.
Inst.de Virología
Fil: Aduriz Guerrero, Matí­as. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Carossino, Mariano. Universidad del Salvador. Escuela de Veterinaria; Argentina. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos
Fil: Go, Y.Y. Korea Research Institute of Chemical Technology. Division of Drug Discovery Research. Virus Research and Testing Group; Corea
Fil: Vincke, Cécile. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica
Fil: Balasuriya,Udeni B.R. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos
Fil: Muyldermans, Serge. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica
Fil: Wigdorovitz, Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; Argentina
Fil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fuente
Journal of equine veterinary science 39 : S56eS65
Materia
Animal Diseases
Stallions
Nanotechnology
Equine Arteritis Virus
Enfermedades de los Animales
Caballos Sementales
Nanotecnología
Virus de la Arteritis Equina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/1009
Acceder
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oai_identifier_str oai:localhost:20.500.12123/1009
network_acronym_str INTADig
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network_name_str INTA Digital (INTA)
spelling Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallionsAduriz Guerrero, Matí­asCarossino, MarianoGo, Y.Y.Vincke, CécileBalasuriya, Udeni B.R.Muyldermans, S.Wigdorovitz, AndresBarrandeguy, Maria EdithParreño, VivianaAnimal DiseasesStallionsNanotechnologyEquine Arteritis VirusEnfermedades de los AnimalesCaballos SementalesNanotecnologíaVirus de la Arteritis EquinaIn conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions.Inst.de VirologíaFil: Aduriz Guerrero, Matí­as. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Carossino, Mariano. Universidad del Salvador. Escuela de Veterinaria; Argentina. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados UnidosFil: Go, Y.Y. Korea Research Institute of Chemical Technology. Division of Drug Discovery Research. Virus Research and Testing Group; CoreaFil: Vincke, Cécile. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; BélgicaFil: Balasuriya,Udeni B.R. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados UnidosFil: Muyldermans, Serge. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; BélgicaFil: Wigdorovitz, Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; ArgentinaFil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina2017-08-22T17:55:12Z2017-08-22T17:55:12Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/1009http://www.j-evs.com/article/S0737-0806(16)00154-4/pdf0737-0806http://dx.doi.org/10.1016/j.jevs.2016.02.123Journal of equine veterinary science 39 : S56eS65reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-11T10:22:08Zoai:localhost:20.500.12123/1009instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-11 10:22:09.157INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
title Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
spellingShingle Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
Aduriz Guerrero, Matí­as
Animal Diseases
Stallions
Nanotechnology
Equine Arteritis Virus
Enfermedades de los Animales
Caballos Sementales
Nanotecnología
Virus de la Arteritis Equina
title_short Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
title_full Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
title_fullStr Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
title_full_unstemmed Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
title_sort Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
dc.creator.none.fl_str_mv Aduriz Guerrero, Matí­as
Carossino, Mariano
Go, Y.Y.
Vincke, Cécile
Balasuriya, Udeni B.R.
Muyldermans, S.
Wigdorovitz, Andres
Barrandeguy, Maria Edith
Parreño, Viviana
author Aduriz Guerrero, Matí­as
author_facet Aduriz Guerrero, Matí­as
Carossino, Mariano
Go, Y.Y.
Vincke, Cécile
Balasuriya, Udeni B.R.
Muyldermans, S.
Wigdorovitz, Andres
Barrandeguy, Maria Edith
Parreño, Viviana
author_role author
author2 Carossino, Mariano
Go, Y.Y.
Vincke, Cécile
Balasuriya, Udeni B.R.
Muyldermans, S.
Wigdorovitz, Andres
Barrandeguy, Maria Edith
Parreño, Viviana
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Animal Diseases
Stallions
Nanotechnology
Equine Arteritis Virus
Enfermedades de los Animales
Caballos Sementales
Nanotecnología
Virus de la Arteritis Equina
topic Animal Diseases
Stallions
Nanotechnology
Equine Arteritis Virus
Enfermedades de los Animales
Caballos Sementales
Nanotecnología
Virus de la Arteritis Equina
dc.description.none.fl_txt_mv In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions.
Inst.de Virología
Fil: Aduriz Guerrero, Matí­as. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Carossino, Mariano. Universidad del Salvador. Escuela de Veterinaria; Argentina. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos
Fil: Go, Y.Y. Korea Research Institute of Chemical Technology. Division of Drug Discovery Research. Virus Research and Testing Group; Corea
Fil: Vincke, Cécile. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica
Fil: Balasuriya,Udeni B.R. University of Kentucky. Department of Veterinary Science. Maxwell H. Gluck Equine Research Center; Estados Unidos
Fil: Muyldermans, Serge. Vrije Universiteit. Laboratory of Cellular and MolecularImmunology; Bélgica
Fil: Wigdorovitz, Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; Argentina
Fil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
description In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce clearance of EAV carrier state in stallions.
publishDate 2016
dc.date.none.fl_str_mv 2016
2017-08-22T17:55:12Z
2017-08-22T17:55:12Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/1009
http://www.j-evs.com/article/S0737-0806(16)00154-4/pdf
0737-0806
http://dx.doi.org/10.1016/j.jevs.2016.02.123
url http://hdl.handle.net/20.500.12123/1009
http://www.j-evs.com/article/S0737-0806(16)00154-4/pdf
http://dx.doi.org/10.1016/j.jevs.2016.02.123
identifier_str_mv 0737-0806
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Journal of equine veterinary science 39 : S56eS65
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.993085

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