The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP

Autores
Miranda de la Torre, Julián O.; Peppino Margutti, Micaela Y.; Lescano Lopez, Carlos Ignacio; Cambiagno, Damian Alejandro; Alvarez, María E.; Cecchini, Nicolás M.
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP.
Instituto de Fisiología y Recursos Genéticos Vegetales
Fil: Miranda de la Torre, Julián O. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Miranda de la Torre, Julián O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Peppino Margutti, Micaela Y. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Peppino Margutti, Micaela Y. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Lescano Lopez, Carlos Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; Argentina
Fil: Lescano Lopez, Carlos Ignacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina
Fil: Lescano Lopez, Carlos Ignacio. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Lescano Lopez, Carlos Ignacio.Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Cambiagno, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; Argentina
Fil: Cambiagno, Damian Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina
Fil: Cambiagno, Damian Alejandro.Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Alvarez, María E. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Cecchini, Nicolás M. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fuente
Frontiers in Plant Science 14 : 1133327 (09 May 2023)
Materia
Arabidopsis
Chromatin
Cromatina
Azelaic Acid
Pipecolic Acid
B-Aminobutyric Acid
Plant Defense
Priming
MOM1
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/15128
Acceder
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oai_identifier_str oai:localhost:20.500.12123/15128
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network_name_str INTA Digital (INTA)
spelling The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIPMiranda de la Torre, Julián O.Peppino Margutti, Micaela Y.Lescano Lopez, Carlos IgnacioCambiagno, Damian AlejandroAlvarez, María E.Cecchini, Nicolás M.ArabidopsisChromatinCromatinaAzelaic AcidPipecolic AcidB-Aminobutyric AcidPlant DefensePrimingMOM1In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP.Instituto de Fisiología y Recursos Genéticos VegetalesFil: Miranda de la Torre, Julián O. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Miranda de la Torre, Julián O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; ArgentinaFil: Peppino Margutti, Micaela Y. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Peppino Margutti, Micaela Y. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; ArgentinaFil: Lescano Lopez, Carlos Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; ArgentinaFil: Lescano Lopez, Carlos Ignacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; ArgentinaFil: Lescano Lopez, Carlos Ignacio. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Lescano Lopez, Carlos Ignacio.Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; ArgentinaFil: Cambiagno, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; ArgentinaFil: Cambiagno, Damian Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; ArgentinaFil: Cambiagno, Damian Alejandro.Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Alvarez, María E. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; ArgentinaFil: Cecchini, Nicolás M. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; ArgentinaFrontiers Media2023-09-07T09:59:05Z2023-09-07T09:59:05Z2023-05-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/15128https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full1664-462X (online)https://doi.org/10.3389/fpls.2023.1133327Frontiers in Plant Science 14 : 1133327 (09 May 2023)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-29T13:46:04Zoai:localhost:20.500.12123/15128instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:46:04.918INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
title The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
spellingShingle The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
Miranda de la Torre, Julián O.
Arabidopsis
Chromatin
Cromatina
Azelaic Acid
Pipecolic Acid
B-Aminobutyric Acid
Plant Defense
Priming
MOM1
title_short The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
title_full The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
title_fullStr The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
title_full_unstemmed The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
title_sort The Arabidopsis chromatin regulator MOM1 is a negative component of the defense priming induced by AZA, BABA and PIP
dc.creator.none.fl_str_mv Miranda de la Torre, Julián O.
Peppino Margutti, Micaela Y.
Lescano Lopez, Carlos Ignacio
Cambiagno, Damian Alejandro
Alvarez, María E.
Cecchini, Nicolás M.
author Miranda de la Torre, Julián O.
author_facet Miranda de la Torre, Julián O.
Peppino Margutti, Micaela Y.
Lescano Lopez, Carlos Ignacio
Cambiagno, Damian Alejandro
Alvarez, María E.
Cecchini, Nicolás M.
author_role author
author2 Peppino Margutti, Micaela Y.
Lescano Lopez, Carlos Ignacio
Cambiagno, Damian Alejandro
Alvarez, María E.
Cecchini, Nicolás M.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Arabidopsis
Chromatin
Cromatina
Azelaic Acid
Pipecolic Acid
B-Aminobutyric Acid
Plant Defense
Priming
MOM1
topic Arabidopsis
Chromatin
Cromatina
Azelaic Acid
Pipecolic Acid
B-Aminobutyric Acid
Plant Defense
Priming
MOM1
dc.description.none.fl_txt_mv In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP.
Instituto de Fisiología y Recursos Genéticos Vegetales
Fil: Miranda de la Torre, Julián O. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Miranda de la Torre, Julián O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Peppino Margutti, Micaela Y. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Peppino Margutti, Micaela Y. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Lescano Lopez, Carlos Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; Argentina
Fil: Lescano Lopez, Carlos Ignacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina
Fil: Lescano Lopez, Carlos Ignacio. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Lescano Lopez, Carlos Ignacio.Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Cambiagno, Damian Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA) ; Argentina
Fil: Cambiagno, Damian Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; Argentina
Fil: Cambiagno, Damian Alejandro.Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina
Fil: Alvarez, María E. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
Fil: Cecchini, Nicolás M. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC). Departamento de Química Biológica-Ranwel Caputto; Argentina
description In plants, the establishment of broad and long-lasting immunity is based on programs that control systemic resistance and immunological memory or “priming”. Despite not showing activated defenses, a primed plant induces a more efficient response to recurrent infections. Priming might involve chromatin modifications that allow a faster/stronger activation of defense genes. The Arabidopsis chromatin regulator “Morpheus Molecule 1” (MOM1) has been recently suggested as a priming factor affecting the expression of immune receptor genes. Here, we show that mom1 mutants exacerbate the root growth inhibition response triggered by the key defense priming inducers azelaic acid (AZA), β-aminobutyric acid (BABA) and pipecolic acid (PIP). Conversely, mom1 mutants complemented with a minimal version of MOM1 (miniMOM1 plants) are insensitive. Moreover, miniMOM1 is unable to induce systemic resistance against Pseudomonas sp. in response to these inducers. Importantly, AZA, BABA and PIP treatments reduce the MOM1 expression, but not miniMOM1 transcript levels, in systemic tissues. Consistently, several MOM1-regulated immune receptor genes are upregulated during the activation of systemic resistance in WT plants, while this effect is not observed in miniMOM1. Taken together, our results position MOM1 as a chromatin factor that negatively regulates the defense priming induced by AZA, BABA and PIP.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-07T09:59:05Z
2023-09-07T09:59:05Z
2023-05-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/15128
https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full
1664-462X (online)
https://doi.org/10.3389/fpls.2023.1133327
url http://hdl.handle.net/20.500.12123/15128
https://www.frontiersin.org/articles/10.3389/fpls.2023.1133327/full
https://doi.org/10.3389/fpls.2023.1133327
identifier_str_mv 1664-462X (online)
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv Frontiers in Plant Science 14 : 1133327 (09 May 2023)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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