Bovine colostral cells—the often forgotten component of colostrum

Autores
Gonzalez, Diego; Dus Santos, Maria Jose
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4
Instituto de Virología
Fil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fuente
Journal of the American Veterinary Medical Association 250 (9) : 998-1005 (Mayo 2017)
Materia
Colostrum
Immune Response
Antigens
Vaccines
Calves
Calostro
Respuesta Inmunológica
Antígenos
Vacuna
Ternero
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/3995

id INTADig_9a0b5314d290eabc18ca150273e578f2
oai_identifier_str oai:localhost:20.500.12123/3995
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Bovine colostral cells—the often forgotten component of colostrumGonzalez, DiegoDus Santos, Maria JoseColostrumImmune ResponseAntigensVaccinesCalvesCalostroRespuesta InmunológicaAntígenosVacunaTerneroAt birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4Instituto de VirologíaFil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaAmerican Veterinary Medical Association2018-12-03T11:25:58Z2018-12-03T11:25:58Z2017-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javmahttp://hdl.handle.net/20.500.12123/39950003-1488https://doi.org/10.2460/javma.250.9.998Journal of the American Veterinary Medical Association 250 (9) : 998-1005 (Mayo 2017)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-04T09:47:42Zoai:localhost:20.500.12123/3995instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:47:43.047INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Bovine colostral cells—the often forgotten component of colostrum
title Bovine colostral cells—the often forgotten component of colostrum
spellingShingle Bovine colostral cells—the often forgotten component of colostrum
Gonzalez, Diego
Colostrum
Immune Response
Antigens
Vaccines
Calves
Calostro
Respuesta Inmunológica
Antígenos
Vacuna
Ternero
title_short Bovine colostral cells—the often forgotten component of colostrum
title_full Bovine colostral cells—the often forgotten component of colostrum
title_fullStr Bovine colostral cells—the often forgotten component of colostrum
title_full_unstemmed Bovine colostral cells—the often forgotten component of colostrum
title_sort Bovine colostral cells—the often forgotten component of colostrum
dc.creator.none.fl_str_mv Gonzalez, Diego
Dus Santos, Maria Jose
author Gonzalez, Diego
author_facet Gonzalez, Diego
Dus Santos, Maria Jose
author_role author
author2 Dus Santos, Maria Jose
author2_role author
dc.subject.none.fl_str_mv Colostrum
Immune Response
Antigens
Vaccines
Calves
Calostro
Respuesta Inmunológica
Antígenos
Vacuna
Ternero
topic Colostrum
Immune Response
Antigens
Vaccines
Calves
Calostro
Respuesta Inmunológica
Antígenos
Vacuna
Ternero
dc.description.none.fl_txt_mv At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4
Instituto de Virología
Fil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
description At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4
publishDate 2017
dc.date.none.fl_str_mv 2017-05
2018-12-03T11:25:58Z
2018-12-03T11:25:58Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javma
http://hdl.handle.net/20.500.12123/3995
0003-1488
https://doi.org/10.2460/javma.250.9.998
url https://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javma
http://hdl.handle.net/20.500.12123/3995
https://doi.org/10.2460/javma.250.9.998
identifier_str_mv 0003-1488
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Veterinary Medical Association
publisher.none.fl_str_mv American Veterinary Medical Association
dc.source.none.fl_str_mv Journal of the American Veterinary Medical Association 250 (9) : 998-1005 (Mayo 2017)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
_version_ 1842341361242603520
score 12.623145