Bovine colostral cells : the often forgotten component of colostrum

Autores
Gonzalez, Diego; Dus Santos, Maria Jose
Año de publicación
2017
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease during this critical period. Cattle producers routinely feed newborn calves fresh (ie, never frozen) or frozen colostrum, which contains antibodies against pathogens within the local environment; however, antibodies are not the sole constituents of colostrum and passively acquired immunity. In addition to maternally derived antibodies, colostrum contains immunologically important cytokines and a large number of maternally derived (materBovine nal) leukocytes, which collectively contribute to the immunoprotection of the neonate.13–16 Although the role of colostral antibodies in the protection of neonates against disease has been well documented,17–20 the role of colostral cellular components in passive immunity is less well understood.21–28 In the early 1970s, researchers began to suggest that maternal lymphocytes in colostrum were primed antigen-responsive cells that, when ingested soon after birth, penetrate the permeable intestinal wall and provide transient local or systemic cell-mediated immunity, the breadth of which reflects the antigenic exposure of the cow from which the colostrum was acquired.
Instituto de Virología
Fil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fuente
JAVMA 250 (9) : 998-1005. (May 1, 2017)
Materia
Bovina
Células
Calostro
Anticuerpos
Inmunidad
Bovinae
Cells
Colostrum
Antibodies
Immunity
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/4445
Acceder
id INTADig_c34cb1180c20b1bddfad934ab39ae613
oai_identifier_str oai:localhost:20.500.12123/4445
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Bovine colostral cells : the often forgotten component of colostrumGonzalez, DiegoDus Santos, Maria JoseBovinaCélulasCalostroAnticuerposInmunidadBovinaeCellsColostrumAntibodiesImmunityBecause bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease during this critical period. Cattle producers routinely feed newborn calves fresh (ie, never frozen) or frozen colostrum, which contains antibodies against pathogens within the local environment; however, antibodies are not the sole constituents of colostrum and passively acquired immunity. In addition to maternally derived antibodies, colostrum contains immunologically important cytokines and a large number of maternally derived (materBovine nal) leukocytes, which collectively contribute to the immunoprotection of the neonate.13–16 Although the role of colostral antibodies in the protection of neonates against disease has been well documented,17–20 the role of colostral cellular components in passive immunity is less well understood.21–28 In the early 1970s, researchers began to suggest that maternal lymphocytes in colostrum were primed antigen-responsive cells that, when ingested soon after birth, penetrate the permeable intestinal wall and provide transient local or systemic cell-mediated immunity, the breadth of which reflects the antigenic exposure of the cow from which the colostrum was acquired.Instituto de VirologíaFil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaFil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; ArgentinaAmerican Veterinary Medical Association2019-02-14T17:38:35Z2019-02-14T17:38:35Z2017-05info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_ba08info:ar-repo/semantics/revisionLiterariaapplication/pdfhttp://hdl.handle.net/20.500.12123/4445https://avmajournals.avma.org/doi/full/10.2460/javma.250.9.9980003-1488JAVMA 250 (9) : 998-1005. (May 1, 2017)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-10-16T09:29:26Zoai:localhost:20.500.12123/4445instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-16 09:29:27.172INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Bovine colostral cells : the often forgotten component of colostrum
title Bovine colostral cells : the often forgotten component of colostrum
spellingShingle Bovine colostral cells : the often forgotten component of colostrum
Gonzalez, Diego
Bovina
Células
Calostro
Anticuerpos
Inmunidad
Bovinae
Cells
Colostrum
Antibodies
Immunity
title_short Bovine colostral cells : the often forgotten component of colostrum
title_full Bovine colostral cells : the often forgotten component of colostrum
title_fullStr Bovine colostral cells : the often forgotten component of colostrum
title_full_unstemmed Bovine colostral cells : the often forgotten component of colostrum
title_sort Bovine colostral cells : the often forgotten component of colostrum
dc.creator.none.fl_str_mv Gonzalez, Diego
Dus Santos, Maria Jose
author Gonzalez, Diego
author_facet Gonzalez, Diego
Dus Santos, Maria Jose
author_role author
author2 Dus Santos, Maria Jose
author2_role author
dc.subject.none.fl_str_mv Bovina
Células
Calostro
Anticuerpos
Inmunidad
Bovinae
Cells
Colostrum
Antibodies
Immunity
topic Bovina
Células
Calostro
Anticuerpos
Inmunidad
Bovinae
Cells
Colostrum
Antibodies
Immunity
dc.description.none.fl_txt_mv Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease during this critical period. Cattle producers routinely feed newborn calves fresh (ie, never frozen) or frozen colostrum, which contains antibodies against pathogens within the local environment; however, antibodies are not the sole constituents of colostrum and passively acquired immunity. In addition to maternally derived antibodies, colostrum contains immunologically important cytokines and a large number of maternally derived (materBovine nal) leukocytes, which collectively contribute to the immunoprotection of the neonate.13–16 Although the role of colostral antibodies in the protection of neonates against disease has been well documented,17–20 the role of colostral cellular components in passive immunity is less well understood.21–28 In the early 1970s, researchers began to suggest that maternal lymphocytes in colostrum were primed antigen-responsive cells that, when ingested soon after birth, penetrate the permeable intestinal wall and provide transient local or systemic cell-mediated immunity, the breadth of which reflects the antigenic exposure of the cow from which the colostrum was acquired.
Instituto de Virología
Fil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
description Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally through the ingestion of colostrum, helps protect calves against disease during this critical period. Cattle producers routinely feed newborn calves fresh (ie, never frozen) or frozen colostrum, which contains antibodies against pathogens within the local environment; however, antibodies are not the sole constituents of colostrum and passively acquired immunity. In addition to maternally derived antibodies, colostrum contains immunologically important cytokines and a large number of maternally derived (materBovine nal) leukocytes, which collectively contribute to the immunoprotection of the neonate.13–16 Although the role of colostral antibodies in the protection of neonates against disease has been well documented,17–20 the role of colostral cellular components in passive immunity is less well understood.21–28 In the early 1970s, researchers began to suggest that maternal lymphocytes in colostrum were primed antigen-responsive cells that, when ingested soon after birth, penetrate the permeable intestinal wall and provide transient local or systemic cell-mediated immunity, the breadth of which reflects the antigenic exposure of the cow from which the colostrum was acquired.
publishDate 2017
dc.date.none.fl_str_mv 2017-05
2019-02-14T17:38:35Z
2019-02-14T17:38:35Z
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_ba08
info:ar-repo/semantics/revisionLiteraria
format review
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/4445
https://avmajournals.avma.org/doi/full/10.2460/javma.250.9.998
0003-1488
url http://hdl.handle.net/20.500.12123/4445
https://avmajournals.avma.org/doi/full/10.2460/javma.250.9.998
identifier_str_mv 0003-1488
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv American Veterinary Medical Association
publisher.none.fl_str_mv American Veterinary Medical Association
dc.source.none.fl_str_mv JAVMA 250 (9) : 998-1005. (May 1, 2017)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
_version_ 1846143511085187072
score 12.711113

Publicaciones similares