Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance...

Autores
Franco, Mariana C.; Soria, Mario; Federico, Francisco Javier; Zapata, Roberto A.; Hamet, María Fernanda; Gallinger, Claudia Isabel; De Antoni, Graciela L.; Peláez, Angela M.L.; Basiouni, Shereen; Bueno, Dante Javier
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Kefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted to evaluate the effect of the microbial fraction of kefir and four strains of Lactiplantibacillus plantarum subsp. plantarum (MFKLP) with promising in vitro probiotic properties, applied in drinking water, and AGP on different parameters in broiler chickens for 28 days. Compared to AGP alone, the MFKLP-AGP consumption decreased the percentage of liver lipids by 24% and 34% at 21 and 28 days of age, respectively. Furthermore, it modified the percentage of some types of leukocytes. It decreased the percentage of eosinophil from 1.8% to 0.2% at day 7, decreased the percentage of lymphocytes, and increased the percentage of heterophils and the heterophil/lymphocyte ratio from 72.8% to 58.6%, 21.6% to 34.8%, and 0.3 to 0.6 at 21 days of age, respectively, and increased the percentage of monocytes from 4.7% to 5.4% at 28 days of age. It also increased the percentage of monocytes at 28 days of age and decreased the crypt depth, and increased the villus height to crypt depth ratio and microbial community diversity at days 21 and 28. The concurrent supplementation of MFKLP and AGP is beneficial for gut and liver health, and this supports the case for continuing research into the use of MFKLP for developing health-promoting functional feed for poultry.
EEA Concepción del Uruguay
Fil: Franco, Mariana C. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Franco, Mariana C. Universidad Nacional de La Plata; Argentina
Fil: Franco, Mariana C. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Soria, Mario Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: Federico, Francisco Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: Zapata, Roberto A. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Hamet, María Fernanda. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Gallinger, Claudia Isabel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: De Antoni, Graciela L. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Peláez, Angela M.L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Basiouni, Shereen. Johannes-Gutenberg University. Institute of Molecular Physiology. Cilia Cell Biology; Alemania
Fil: Bueno, Dante Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: Bueno, Dante Javier. Universidad Autónoma de Entre Ríos: Sede Basavilbaso. Facultad de Ciencia y Tecnología; Argentina
Fuente
German Journal of Veterinary Research 5 (2): 73-89. (2025)
Materia
Pollo de Engorde
Suplementos
Flora Microbiana
Bacteria Acidoláctica
Broiler Chickens
Supplements
Lactobacillus plantarum
Kefir
Microbial Flora
Lactic Acid Bacteria
Lactiplantibacillus plantarum
Microbiota
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/23185
Acceder
id INTADig_5a5fce94d32fcaf9ce0846271ce50a7e
oai_identifier_str oai:localhost:20.500.12123/23185
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickensFranco, Mariana C.Soria, MarioFederico, Francisco JavierZapata, Roberto A.Hamet, María FernandaGallinger, Claudia IsabelDe Antoni, Graciela L.Peláez, Angela M.L.Basiouni, ShereenBueno, Dante JavierPollo de EngordeSuplementosFlora MicrobianaBacteria AcidolácticaBroiler ChickensSupplementsLactobacillus plantarumKefirMicrobial FloraLactic Acid BacteriaLactiplantibacillus plantarumMicrobiotaKefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted to evaluate the effect of the microbial fraction of kefir and four strains of Lactiplantibacillus plantarum subsp. plantarum (MFKLP) with promising in vitro probiotic properties, applied in drinking water, and AGP on different parameters in broiler chickens for 28 days. Compared to AGP alone, the MFKLP-AGP consumption decreased the percentage of liver lipids by 24% and 34% at 21 and 28 days of age, respectively. Furthermore, it modified the percentage of some types of leukocytes. It decreased the percentage of eosinophil from 1.8% to 0.2% at day 7, decreased the percentage of lymphocytes, and increased the percentage of heterophils and the heterophil/lymphocyte ratio from 72.8% to 58.6%, 21.6% to 34.8%, and 0.3 to 0.6 at 21 days of age, respectively, and increased the percentage of monocytes from 4.7% to 5.4% at 28 days of age. It also increased the percentage of monocytes at 28 days of age and decreased the crypt depth, and increased the villus height to crypt depth ratio and microbial community diversity at days 21 and 28. The concurrent supplementation of MFKLP and AGP is beneficial for gut and liver health, and this supports the case for continuing research into the use of MFKLP for developing health-promoting functional feed for poultry.EEA Concepción del UruguayFil: Franco, Mariana C. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Franco, Mariana C. Universidad Nacional de La Plata; ArgentinaFil: Franco, Mariana C. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; ArgentinaFil: Soria, Mario Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; ArgentinaFil: Federico, Francisco Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; ArgentinaFil: Zapata, Roberto A. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; ArgentinaFil: Hamet, María Fernanda. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; ArgentinaFil: Gallinger, Claudia Isabel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; ArgentinaFil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; ArgentinaFil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: De Antoni, Graciela L. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Peláez, Angela M.L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; ArgentinaFil: Basiouni, Shereen. Johannes-Gutenberg University. Institute of Molecular Physiology. Cilia Cell Biology; AlemaniaFil: Bueno, Dante Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; ArgentinaFil: Bueno, Dante Javier. Universidad Autónoma de Entre Ríos: Sede Basavilbaso. Facultad de Ciencia y Tecnología; ArgentinaGerman Multidisciplinary Publishing Center (GMPC)2025-07-28T14:35:24Z2025-07-28T14:35:24Z2025-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/23185https://gmpc-akademie.de/articles/gjvr/single/2752703-1322https://doi.org/10.51585/gjvr.2025.2.0136German Journal of Veterinary Research 5 (2): 73-89. (2025)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2023-PD-L06-I115, Resistencia Antimicrobiana y desarrollo de alternativas que minimicen el uso de antibióticos y antiparasitarios para una produccion animal mas sustentableinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-10-16T09:32:27Zoai:localhost:20.500.12123/23185instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-16 09:32:27.73INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
spellingShingle Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
Franco, Mariana C.
Pollo de Engorde
Suplementos
Flora Microbiana
Bacteria Acidoláctica
Broiler Chickens
Supplements
Lactobacillus plantarum
Kefir
Microbial Flora
Lactic Acid Bacteria
Lactiplantibacillus plantarum
Microbiota
title_short Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_full Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_fullStr Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_full_unstemmed Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
title_sort Simultaneous supplementation of the microbial fraction of kefir containing Lactiplantibacillus plantarum subspecies plantarum strains and antibiotic growth promoters on performance, gut microbiota, and health parameters in broiler chickens
dc.creator.none.fl_str_mv Franco, Mariana C.
Soria, Mario
Federico, Francisco Javier
Zapata, Roberto A.
Hamet, María Fernanda
Gallinger, Claudia Isabel
De Antoni, Graciela L.
Peláez, Angela M.L.
Basiouni, Shereen
Bueno, Dante Javier
author Franco, Mariana C.
author_facet Franco, Mariana C.
Soria, Mario
Federico, Francisco Javier
Zapata, Roberto A.
Hamet, María Fernanda
Gallinger, Claudia Isabel
De Antoni, Graciela L.
Peláez, Angela M.L.
Basiouni, Shereen
Bueno, Dante Javier
author_role author
author2 Soria, Mario
Federico, Francisco Javier
Zapata, Roberto A.
Hamet, María Fernanda
Gallinger, Claudia Isabel
De Antoni, Graciela L.
Peláez, Angela M.L.
Basiouni, Shereen
Bueno, Dante Javier
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Pollo de Engorde
Suplementos
Flora Microbiana
Bacteria Acidoláctica
Broiler Chickens
Supplements
Lactobacillus plantarum
Kefir
Microbial Flora
Lactic Acid Bacteria
Lactiplantibacillus plantarum
Microbiota
topic Pollo de Engorde
Suplementos
Flora Microbiana
Bacteria Acidoláctica
Broiler Chickens
Supplements
Lactobacillus plantarum
Kefir
Microbial Flora
Lactic Acid Bacteria
Lactiplantibacillus plantarum
Microbiota
dc.description.none.fl_txt_mv Kefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted to evaluate the effect of the microbial fraction of kefir and four strains of Lactiplantibacillus plantarum subsp. plantarum (MFKLP) with promising in vitro probiotic properties, applied in drinking water, and AGP on different parameters in broiler chickens for 28 days. Compared to AGP alone, the MFKLP-AGP consumption decreased the percentage of liver lipids by 24% and 34% at 21 and 28 days of age, respectively. Furthermore, it modified the percentage of some types of leukocytes. It decreased the percentage of eosinophil from 1.8% to 0.2% at day 7, decreased the percentage of lymphocytes, and increased the percentage of heterophils and the heterophil/lymphocyte ratio from 72.8% to 58.6%, 21.6% to 34.8%, and 0.3 to 0.6 at 21 days of age, respectively, and increased the percentage of monocytes from 4.7% to 5.4% at 28 days of age. It also increased the percentage of monocytes at 28 days of age and decreased the crypt depth, and increased the villus height to crypt depth ratio and microbial community diversity at days 21 and 28. The concurrent supplementation of MFKLP and AGP is beneficial for gut and liver health, and this supports the case for continuing research into the use of MFKLP for developing health-promoting functional feed for poultry.
EEA Concepción del Uruguay
Fil: Franco, Mariana C. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Franco, Mariana C. Universidad Nacional de La Plata; Argentina
Fil: Franco, Mariana C. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Soria, Mario Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: Federico, Francisco Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: Zapata, Roberto A. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Hamet, María Fernanda. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Gallinger, Claudia Isabel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: De Antoni, Graciela L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: De Antoni, Graciela L. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
Fil: Peláez, Angela M.L. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Cátedra de Microbiología; Argentina
Fil: Basiouni, Shereen. Johannes-Gutenberg University. Institute of Molecular Physiology. Cilia Cell Biology; Alemania
Fil: Bueno, Dante Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Concepción del Uruguay; Argentina
Fil: Bueno, Dante Javier. Universidad Autónoma de Entre Ríos: Sede Basavilbaso. Facultad de Ciencia y Tecnología; Argentina
description Kefir contains lactic acid bacteria and yeasts, which are involved in fermentation and contribute to its probiotic effects. The simultaneous supplementation feeding of antibiotics and probiotics could serve as a way to replace antibiotic growth promoters (AGP) gradually. So, this study was conducted to evaluate the effect of the microbial fraction of kefir and four strains of Lactiplantibacillus plantarum subsp. plantarum (MFKLP) with promising in vitro probiotic properties, applied in drinking water, and AGP on different parameters in broiler chickens for 28 days. Compared to AGP alone, the MFKLP-AGP consumption decreased the percentage of liver lipids by 24% and 34% at 21 and 28 days of age, respectively. Furthermore, it modified the percentage of some types of leukocytes. It decreased the percentage of eosinophil from 1.8% to 0.2% at day 7, decreased the percentage of lymphocytes, and increased the percentage of heterophils and the heterophil/lymphocyte ratio from 72.8% to 58.6%, 21.6% to 34.8%, and 0.3 to 0.6 at 21 days of age, respectively, and increased the percentage of monocytes from 4.7% to 5.4% at 28 days of age. It also increased the percentage of monocytes at 28 days of age and decreased the crypt depth, and increased the villus height to crypt depth ratio and microbial community diversity at days 21 and 28. The concurrent supplementation of MFKLP and AGP is beneficial for gut and liver health, and this supports the case for continuing research into the use of MFKLP for developing health-promoting functional feed for poultry.
publishDate 2025
dc.date.none.fl_str_mv 2025-07-28T14:35:24Z
2025-07-28T14:35:24Z
2025-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/23185
https://gmpc-akademie.de/articles/gjvr/single/275
2703-1322
https://doi.org/10.51585/gjvr.2025.2.0136
url http://hdl.handle.net/20.500.12123/23185
https://gmpc-akademie.de/articles/gjvr/single/275
https://doi.org/10.51585/gjvr.2025.2.0136
identifier_str_mv 2703-1322
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2023-PD-L06-I115, Resistencia Antimicrobiana y desarrollo de alternativas que minimicen el uso de antibióticos y antiparasitarios para una produccion animal mas sustentable
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv German Multidisciplinary Publishing Center (GMPC)
publisher.none.fl_str_mv German Multidisciplinary Publishing Center (GMPC)
dc.source.none.fl_str_mv German Journal of Veterinary Research 5 (2): 73-89. (2025)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
_version_ 1846143592361361408
score 12.712165

Publicaciones similares