Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves

Autores
Miqueo, Evangelina; Cruz, Micaela Solange; Moore, Prando Dadin; Campero, Lucia Maria
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina. Calf performance metrics (total intake, daily weight gain, feed efficiency, and fecal consistency) were recorded. Serum samples from cows were collected prepartum, and from calves at birth (pre-colostrum), 7, 14, and 63 days of birth to assess N. caninum antibodies and oxidative status. No differences in total intake, daily weight gain, feed efficiency, or fecal score were observed between N. caninum infected and non-infected calves. Similarly, total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin levels did not differ between groups. Among the 59 cows evaluated, 17 tested seropositive for N. caninum. Of these, 15 gave birth to N. caninum seropositive calves, corresponding to a vertical transmission rate of 88.2 %. Among these cows, higher relative index percentage (RIPC) values were associated with successful vertical transmission (mean RIPC 69.8 vs. 7.8; p = 0.01). Congenitally infected calves also had higher RIPC values compared to those that seroconverted postnatally (mean RIPC 32 vs 17.4; p = 0.02). The absence of oxidative stress differences suggests parasite adaptation in congenitally infected calves without clinical signs. This study highlights a substantial transplacental transmission linked to higher RICP in seropositive cows and limited exposure to N. caninum during the artificial rearing. Results emphasize two factors: higher antibody levels correlated with congenital transmission and the absence of horizontal transmission during dairy calf rearing.
EEA Balcarce
Fil: Miqueo, Evangelina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Cruz, Micaela Solange. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Moore, Dadin Prando. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Moore, Dadin Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Campero, Lucía María. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fuente
Veterinary Parasitology 338 : 110530 (August 2025)
Materia
Neosporosis
Terneros
Estrés de Oxidativo
Trasmisión Vertical
Transmisión Horizontal
Calves
Oxidative Stress
Vertical Transmission
Horizontal Transmission
Dairy Cattle
Neospora caninum
Ganado de Leche
Nivel de accesibilidad
acceso restringido
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/23017
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oai_identifier_str oai:localhost:20.500.12123/23017
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network_name_str INTA Digital (INTA)
spelling Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calvesMiqueo, EvangelinaCruz, Micaela SolangeMoore, Prando DadinCampero, Lucia MariaNeosporosisTernerosEstrés de OxidativoTrasmisión VerticalTransmisión HorizontalCalvesOxidative StressVertical TransmissionHorizontal TransmissionDairy CattleNeospora caninumGanado de LecheThis study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina. Calf performance metrics (total intake, daily weight gain, feed efficiency, and fecal consistency) were recorded. Serum samples from cows were collected prepartum, and from calves at birth (pre-colostrum), 7, 14, and 63 days of birth to assess N. caninum antibodies and oxidative status. No differences in total intake, daily weight gain, feed efficiency, or fecal score were observed between N. caninum infected and non-infected calves. Similarly, total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin levels did not differ between groups. Among the 59 cows evaluated, 17 tested seropositive for N. caninum. Of these, 15 gave birth to N. caninum seropositive calves, corresponding to a vertical transmission rate of 88.2 %. Among these cows, higher relative index percentage (RIPC) values were associated with successful vertical transmission (mean RIPC 69.8 vs. 7.8; p = 0.01). Congenitally infected calves also had higher RIPC values compared to those that seroconverted postnatally (mean RIPC 32 vs 17.4; p = 0.02). The absence of oxidative stress differences suggests parasite adaptation in congenitally infected calves without clinical signs. This study highlights a substantial transplacental transmission linked to higher RICP in seropositive cows and limited exposure to N. caninum during the artificial rearing. Results emphasize two factors: higher antibody levels correlated with congenital transmission and the absence of horizontal transmission during dairy calf rearing.EEA BalcarceFil: Miqueo, Evangelina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; ArgentinaFil: Cruz, Micaela Solange. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; ArgentinaFil: Moore, Dadin Prando. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; ArgentinaFil: Moore, Dadin Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaFil: Campero, Lucía María. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaElsevier2025-07-14T13:48:36Z2025-07-14T13:48:36Z2025-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/23017https://www.sciencedirect.com/science/article/abs/pii/S03044017250014141873-2550 (Online)0304-4017 (Print)https://doi.org/10.1016/j.vetpar.2025.110530Veterinary Parasitology 338 : 110530 (August 2025)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2019-PD-E5-I103-001, Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud públicainfo:eu-repo/semantics/restrictedAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-29T13:47:25Zoai:localhost:20.500.12123/23017instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:47:25.341INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
spellingShingle Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
Miqueo, Evangelina
Neosporosis
Terneros
Estrés de Oxidativo
Trasmisión Vertical
Transmisión Horizontal
Calves
Oxidative Stress
Vertical Transmission
Horizontal Transmission
Dairy Cattle
Neospora caninum
Ganado de Leche
title_short Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_full Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_fullStr Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_full_unstemmed Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
title_sort Oxidative and inflammatory status, daily weight gain, intake and feed efficiency on natural congenitally Neospora caninum infected dairy calves
dc.creator.none.fl_str_mv Miqueo, Evangelina
Cruz, Micaela Solange
Moore, Prando Dadin
Campero, Lucia Maria
author Miqueo, Evangelina
author_facet Miqueo, Evangelina
Cruz, Micaela Solange
Moore, Prando Dadin
Campero, Lucia Maria
author_role author
author2 Cruz, Micaela Solange
Moore, Prando Dadin
Campero, Lucia Maria
author2_role author
author
author
dc.subject.none.fl_str_mv Neosporosis
Terneros
Estrés de Oxidativo
Trasmisión Vertical
Transmisión Horizontal
Calves
Oxidative Stress
Vertical Transmission
Horizontal Transmission
Dairy Cattle
Neospora caninum
Ganado de Leche
topic Neosporosis
Terneros
Estrés de Oxidativo
Trasmisión Vertical
Transmisión Horizontal
Calves
Oxidative Stress
Vertical Transmission
Horizontal Transmission
Dairy Cattle
Neospora caninum
Ganado de Leche
dc.description.none.fl_txt_mv This study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina. Calf performance metrics (total intake, daily weight gain, feed efficiency, and fecal consistency) were recorded. Serum samples from cows were collected prepartum, and from calves at birth (pre-colostrum), 7, 14, and 63 days of birth to assess N. caninum antibodies and oxidative status. No differences in total intake, daily weight gain, feed efficiency, or fecal score were observed between N. caninum infected and non-infected calves. Similarly, total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin levels did not differ between groups. Among the 59 cows evaluated, 17 tested seropositive for N. caninum. Of these, 15 gave birth to N. caninum seropositive calves, corresponding to a vertical transmission rate of 88.2 %. Among these cows, higher relative index percentage (RIPC) values were associated with successful vertical transmission (mean RIPC 69.8 vs. 7.8; p = 0.01). Congenitally infected calves also had higher RIPC values compared to those that seroconverted postnatally (mean RIPC 32 vs 17.4; p = 0.02). The absence of oxidative stress differences suggests parasite adaptation in congenitally infected calves without clinical signs. This study highlights a substantial transplacental transmission linked to higher RICP in seropositive cows and limited exposure to N. caninum during the artificial rearing. Results emphasize two factors: higher antibody levels correlated with congenital transmission and the absence of horizontal transmission during dairy calf rearing.
EEA Balcarce
Fil: Miqueo, Evangelina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Cruz, Micaela Solange. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Moore, Dadin Prando. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Moore, Dadin Prando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Campero, Lucía María. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
description This study explored the effect of Neospora caninum infection on oxidative and inflammatory status in newborn dairy calves and the relationship between antibody levels in dairy cows and congenital transmission. The study involved 59 cow-calf pairs from a dairy herd in Mar y Sierras Basin, Argentina. Calf performance metrics (total intake, daily weight gain, feed efficiency, and fecal consistency) were recorded. Serum samples from cows were collected prepartum, and from calves at birth (pre-colostrum), 7, 14, and 63 days of birth to assess N. caninum antibodies and oxidative status. No differences in total intake, daily weight gain, feed efficiency, or fecal score were observed between N. caninum infected and non-infected calves. Similarly, total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin levels did not differ between groups. Among the 59 cows evaluated, 17 tested seropositive for N. caninum. Of these, 15 gave birth to N. caninum seropositive calves, corresponding to a vertical transmission rate of 88.2 %. Among these cows, higher relative index percentage (RIPC) values were associated with successful vertical transmission (mean RIPC 69.8 vs. 7.8; p = 0.01). Congenitally infected calves also had higher RIPC values compared to those that seroconverted postnatally (mean RIPC 32 vs 17.4; p = 0.02). The absence of oxidative stress differences suggests parasite adaptation in congenitally infected calves without clinical signs. This study highlights a substantial transplacental transmission linked to higher RICP in seropositive cows and limited exposure to N. caninum during the artificial rearing. Results emphasize two factors: higher antibody levels correlated with congenital transmission and the absence of horizontal transmission during dairy calf rearing.
publishDate 2025
dc.date.none.fl_str_mv 2025-07-14T13:48:36Z
2025-07-14T13:48:36Z
2025-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/23017
https://www.sciencedirect.com/science/article/abs/pii/S0304401725001414
1873-2550 (Online)
0304-4017 (Print)
https://doi.org/10.1016/j.vetpar.2025.110530
url http://hdl.handle.net/20.500.12123/23017
https://www.sciencedirect.com/science/article/abs/pii/S0304401725001414
https://doi.org/10.1016/j.vetpar.2025.110530
identifier_str_mv 1873-2550 (Online)
0304-4017 (Print)
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2019-PD-E5-I103-001, Desarrollo de tecnologías diagnósticas y estudios epidemiológicos para el control de enfermedades que afectan la producción animal y la salud pública
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv restrictedAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Veterinary Parasitology 338 : 110530 (August 2025)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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