Babesia life cycle – When phylogeny meets biology

Autores
Jalovecka, Marie; Sojka, Daniel; Ascencio, Mariano E.; Schnittger, Leonhard
Año de publicación
2019
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.
Instituto de Patobiología
Fil: Jalovecka, Marie. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa. University of South Bohemia. Faculty of Science; República Checa
Fil: Sojka, Daniel. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa
Fil: Ascencio, Mariano E. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Schnittger, Leonhard. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fuente
Trends in parasitology. (4 February 2019)
Materia
Babesia
Ciclo Vital
Filogenia
Biología
Metastigmata
Biología Molecular
Life Cycle
Phylogeny
Biology
Molecular Biology
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/4744
Acceder
id INTADig_4cd148962c92246c43f85e70186eca98
oai_identifier_str oai:localhost:20.500.12123/4744
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Babesia life cycle – When phylogeny meets biologyJalovecka, MarieSojka, DanielAscencio, Mariano E.Schnittger, LeonhardBabesiaCiclo VitalFilogeniaBiologíaMetastigmataBiología MolecularLife CyclePhylogenyBiologyMolecular BiologyAlthough Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.Instituto de PatobiologíaFil: Jalovecka, Marie. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa. University of South Bohemia. Faculty of Science; República ChecaFil: Sojka, Daniel. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República ChecaFil: Ascencio, Mariano E. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Schnittger, Leonhard. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2019-03-26T15:34:34Z2019-03-26T15:34:34Z2019-02-04info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdfhttp://hdl.handle.net/20.500.12123/4744https://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub1471-4922https://doi.org/10.1016/j.pt.2019.01.007Trends in parasitology. (4 February 2019)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-04T09:47:54Zoai:localhost:20.500.12123/4744instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:47:54.318INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Babesia life cycle – When phylogeny meets biology
title Babesia life cycle – When phylogeny meets biology
spellingShingle Babesia life cycle – When phylogeny meets biology
Jalovecka, Marie
Babesia
Ciclo Vital
Filogenia
Biología
Metastigmata
Biología Molecular
Life Cycle
Phylogeny
Biology
Molecular Biology
title_short Babesia life cycle – When phylogeny meets biology
title_full Babesia life cycle – When phylogeny meets biology
title_fullStr Babesia life cycle – When phylogeny meets biology
title_full_unstemmed Babesia life cycle – When phylogeny meets biology
title_sort Babesia life cycle – When phylogeny meets biology
dc.creator.none.fl_str_mv Jalovecka, Marie
Sojka, Daniel
Ascencio, Mariano E.
Schnittger, Leonhard
author Jalovecka, Marie
author_facet Jalovecka, Marie
Sojka, Daniel
Ascencio, Mariano E.
Schnittger, Leonhard
author_role author
author2 Sojka, Daniel
Ascencio, Mariano E.
Schnittger, Leonhard
author2_role author
author
author
dc.subject.none.fl_str_mv Babesia
Ciclo Vital
Filogenia
Biología
Metastigmata
Biología Molecular
Life Cycle
Phylogeny
Biology
Molecular Biology
topic Babesia
Ciclo Vital
Filogenia
Biología
Metastigmata
Biología Molecular
Life Cycle
Phylogeny
Biology
Molecular Biology
dc.description.none.fl_txt_mv Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.
Instituto de Patobiología
Fil: Jalovecka, Marie. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa. University of South Bohemia. Faculty of Science; República Checa
Fil: Sojka, Daniel. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa
Fil: Ascencio, Mariano E. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Schnittger, Leonhard. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.
publishDate 2019
dc.date.none.fl_str_mv 2019-03-26T15:34:34Z
2019-03-26T15:34:34Z
2019-02-04
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_dcae04bc
info:ar-repo/semantics/resenaArticulo
format review
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/4744
https://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub
1471-4922
https://doi.org/10.1016/j.pt.2019.01.007
url http://hdl.handle.net/20.500.12123/4744
https://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub
https://doi.org/10.1016/j.pt.2019.01.007
identifier_str_mv 1471-4922
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Trends in parasitology. (4 February 2019)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
_version_ 1842341364524646400
score 12.623145

Publicaciones similares