Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis
- Autores
- Ricardo, Tamara; Bazán Domínguez, Ludmila R.; Beltramini, Lucila; Prieto, Yanina; Montiel, Anahí; Margenet, Leticia; Schmeling, María Fernanda; Chiani, Yosena; Signorini Porchiett, Marcelo Lisandro; Previtali, M. Andrea
- Año de publicación
- 2024
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- This study examines household pets as potential epidemiological links between environments contaminated with pathogenic leptospires and humans in Santa Fe, Argentina. The aims of our study were: (a) to characterize the habits and exposure to environmental sources of leptospirosis in the population of dogs and cats attending to municipal spay and neutering campaigns in Santa Fe, Argentina, (b) to assess the seroprevalence of anti-Leptospira antibodies in asymptomatic dogs and cats, (c) to evaluate factors that could increase seropositivity, and (d) to identify spatial clusters of seropositive dogs and cats in the capital city of Santa Fe. From May to November 2022, a cross-sectional serosurvey was conducted during municipal spaying/neutering campaigns. Eligible household dogs and cats were over 6 months old, apparently healthy, and not vaccinated against leptospirosis in the past 6 months. We used microagglutination test (MAT) to assess anti-Leptospira antibodies using a panel of 10 reference strains. We used generalized linear mixed effects models (GLMM) to examine individual and census tract-level risk factors for seropositivity, and local Moran’s I statistic for spatial clusters. Results showed higher leptospiral antibody prevalence in dogs (18.2 %) than cats (3.6 %, p = 0.002). Dogs with street access had higher likelihood of being seropositive (OR: 3.8, 95 % CI: 1.2; 11.9), and areas with chronic poverty showed an elevated risk of presenting seropositive animals (RR: 4.0, 95 % CI: 1.1; 14.4). Spatial analysis didn't reveal significant seropositivity clusters among census tracts. These findings shed light on widespread Leptospira seropositivity in pets in this endemic region. Understanding seroprevalence and risk factors can guide public and veterinary health strategies, emphasizing increased leptospirosis vaccination for dogs in vulnerable areas and promoting responsible pet care.
EEA Rafaela
Fil: Ricardo, Tamara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Ricardo, Tamara. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; Argentina
Fil: Bazán Domínguez, Ludmila R. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; Argentina
Fil: Beltramini, Lucila. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); Argentina
Fil: Prieto, Yanina. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); Argentina
Fil: Prieto, Yanina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Centro de Investigación sobre Endemias Nacionales (CIEN); Argentina
Fil: Montiel, Anahí. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); Argentina
Fil: Schmeling, María Fernanda. Administración Nacional de Laboratorios e Institutos de Salud (ANLIS). Instituto Nacional de Enfermedades Respiratorias “Dr. E. Coni”; Argentina
Fil: Chiani, Yosena. Administración Nacional de Laboratorios e Institutos de Salud (ANLIS). Instituto Nacional de Enfermedades Respiratorias “Dr. E. Coni”; Argentina
Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina
Fil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina
Fil: Previtali, M. Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Previtali, M. Andrea. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; Argentina - Fuente
- Preventive Veterinary Medicine 229 : 106239. (August 2024)
- Materia
-
Enfermedades de los Animales
Anticuerpos
Perro
Gato
Animal de Compañía
Animal Diseases
Leptospira
Antibodies
Dogs
Cats
Pet Animals
Leptospirosis
Ciudad de Santa Fé, Argentina - Nivel de accesibilidad
- acceso restringido
- Condiciones de uso
- http://creativecommons.org/licenses/by-nc-sa/4.0/
- Repositorio
.jpg)
- Institución
- Instituto Nacional de Tecnología Agropecuaria
- OAI Identificador
- oai:localhost:20.500.12123/22166
Ver los metadatos del registro completo
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Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosisRicardo, TamaraBazán Domínguez, Ludmila R.Beltramini, LucilaPrieto, YaninaMontiel, AnahíMargenet, LeticiaSchmeling, María FernandaChiani, YosenaSignorini Porchiett, Marcelo LisandroPrevitali, M. AndreaEnfermedades de los AnimalesAnticuerposPerroGatoAnimal de CompañíaAnimal DiseasesLeptospiraAntibodiesDogsCatsPet AnimalsLeptospirosisCiudad de Santa Fé, ArgentinaThis study examines household pets as potential epidemiological links between environments contaminated with pathogenic leptospires and humans in Santa Fe, Argentina. The aims of our study were: (a) to characterize the habits and exposure to environmental sources of leptospirosis in the population of dogs and cats attending to municipal spay and neutering campaigns in Santa Fe, Argentina, (b) to assess the seroprevalence of anti-Leptospira antibodies in asymptomatic dogs and cats, (c) to evaluate factors that could increase seropositivity, and (d) to identify spatial clusters of seropositive dogs and cats in the capital city of Santa Fe. From May to November 2022, a cross-sectional serosurvey was conducted during municipal spaying/neutering campaigns. Eligible household dogs and cats were over 6 months old, apparently healthy, and not vaccinated against leptospirosis in the past 6 months. We used microagglutination test (MAT) to assess anti-Leptospira antibodies using a panel of 10 reference strains. We used generalized linear mixed effects models (GLMM) to examine individual and census tract-level risk factors for seropositivity, and local Moran’s I statistic for spatial clusters. Results showed higher leptospiral antibody prevalence in dogs (18.2 %) than cats (3.6 %, p = 0.002). Dogs with street access had higher likelihood of being seropositive (OR: 3.8, 95 % CI: 1.2; 11.9), and areas with chronic poverty showed an elevated risk of presenting seropositive animals (RR: 4.0, 95 % CI: 1.1; 14.4). Spatial analysis didn't reveal significant seropositivity clusters among census tracts. These findings shed light on widespread Leptospira seropositivity in pets in this endemic region. Understanding seroprevalence and risk factors can guide public and veterinary health strategies, emphasizing increased leptospirosis vaccination for dogs in vulnerable areas and promoting responsible pet care.EEA RafaelaFil: Ricardo, Tamara. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ricardo, Tamara. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; ArgentinaFil: Bazán Domínguez, Ludmila R. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; ArgentinaFil: Beltramini, Lucila. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); ArgentinaFil: Prieto, Yanina. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); ArgentinaFil: Prieto, Yanina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Centro de Investigación sobre Endemias Nacionales (CIEN); ArgentinaFil: Montiel, Anahí. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); ArgentinaFil: Schmeling, María Fernanda. Administración Nacional de Laboratorios e Institutos de Salud (ANLIS). Instituto Nacional de Enfermedades Respiratorias “Dr. E. Coni”; ArgentinaFil: Chiani, Yosena. Administración Nacional de Laboratorios e Institutos de Salud (ANLIS). Instituto Nacional de Enfermedades Respiratorias “Dr. E. Coni”; ArgentinaFil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); ArgentinaFil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); ArgentinaFil: Previtali, M. Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Previtali, M. Andrea. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; ArgentinaElsevier2025-05-06T12:05:33Z2025-05-06T12:05:33Z2024-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/22166https://www.sciencedirect.com/science/article/abs/pii/S01675877240012590167-58771873-1716https://doi.org/10.1016/j.prevetmed.2024.106239Preventive Veterinary Medicine 229 : 106239. (August 2024)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología AgropecuariaengSanta Fé .......... 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| dc.title.none.fl_str_mv |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| title |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| spellingShingle |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis Ricardo, Tamara Enfermedades de los Animales Anticuerpos Perro Gato Animal de Compañía Animal Diseases Leptospira Antibodies Dogs Cats Pet Animals Leptospirosis Ciudad de Santa Fé, Argentina |
| title_short |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| title_full |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| title_fullStr |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| title_full_unstemmed |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| title_sort |
Seroprevalence of Leptospira antibodies in dogs and cats from Santa Fe, a city in East-Central Argentina endemic for leptospirosis |
| dc.creator.none.fl_str_mv |
Ricardo, Tamara Bazán Domínguez, Ludmila R. Beltramini, Lucila Prieto, Yanina Montiel, Anahí Margenet, Leticia Schmeling, María Fernanda Chiani, Yosena Signorini Porchiett, Marcelo Lisandro Previtali, M. Andrea |
| author |
Ricardo, Tamara |
| author_facet |
Ricardo, Tamara Bazán Domínguez, Ludmila R. Beltramini, Lucila Prieto, Yanina Montiel, Anahí Margenet, Leticia Schmeling, María Fernanda Chiani, Yosena Signorini Porchiett, Marcelo Lisandro Previtali, M. Andrea |
| author_role |
author |
| author2 |
Bazán Domínguez, Ludmila R. Beltramini, Lucila Prieto, Yanina Montiel, Anahí Margenet, Leticia Schmeling, María Fernanda Chiani, Yosena Signorini Porchiett, Marcelo Lisandro Previtali, M. Andrea |
| author2_role |
author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Enfermedades de los Animales Anticuerpos Perro Gato Animal de Compañía Animal Diseases Leptospira Antibodies Dogs Cats Pet Animals Leptospirosis Ciudad de Santa Fé, Argentina |
| topic |
Enfermedades de los Animales Anticuerpos Perro Gato Animal de Compañía Animal Diseases Leptospira Antibodies Dogs Cats Pet Animals Leptospirosis Ciudad de Santa Fé, Argentina |
| dc.description.none.fl_txt_mv |
This study examines household pets as potential epidemiological links between environments contaminated with pathogenic leptospires and humans in Santa Fe, Argentina. The aims of our study were: (a) to characterize the habits and exposure to environmental sources of leptospirosis in the population of dogs and cats attending to municipal spay and neutering campaigns in Santa Fe, Argentina, (b) to assess the seroprevalence of anti-Leptospira antibodies in asymptomatic dogs and cats, (c) to evaluate factors that could increase seropositivity, and (d) to identify spatial clusters of seropositive dogs and cats in the capital city of Santa Fe. From May to November 2022, a cross-sectional serosurvey was conducted during municipal spaying/neutering campaigns. Eligible household dogs and cats were over 6 months old, apparently healthy, and not vaccinated against leptospirosis in the past 6 months. We used microagglutination test (MAT) to assess anti-Leptospira antibodies using a panel of 10 reference strains. We used generalized linear mixed effects models (GLMM) to examine individual and census tract-level risk factors for seropositivity, and local Moran’s I statistic for spatial clusters. Results showed higher leptospiral antibody prevalence in dogs (18.2 %) than cats (3.6 %, p = 0.002). Dogs with street access had higher likelihood of being seropositive (OR: 3.8, 95 % CI: 1.2; 11.9), and areas with chronic poverty showed an elevated risk of presenting seropositive animals (RR: 4.0, 95 % CI: 1.1; 14.4). Spatial analysis didn't reveal significant seropositivity clusters among census tracts. These findings shed light on widespread Leptospira seropositivity in pets in this endemic region. Understanding seroprevalence and risk factors can guide public and veterinary health strategies, emphasizing increased leptospirosis vaccination for dogs in vulnerable areas and promoting responsible pet care. EEA Rafaela Fil: Ricardo, Tamara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Ricardo, Tamara. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; Argentina Fil: Bazán Domínguez, Ludmila R. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; Argentina Fil: Beltramini, Lucila. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); Argentina Fil: Prieto, Yanina. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); Argentina Fil: Prieto, Yanina. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Centro de Investigación sobre Endemias Nacionales (CIEN); Argentina Fil: Montiel, Anahí. Gobierno de la Ciudad de Santa Fe. Instituto Municipal de Salud Animal (IMuSA); Argentina Fil: Schmeling, María Fernanda. Administración Nacional de Laboratorios e Institutos de Salud (ANLIS). Instituto Nacional de Enfermedades Respiratorias “Dr. E. Coni”; Argentina Fil: Chiani, Yosena. Administración Nacional de Laboratorios e Institutos de Salud (ANLIS). Instituto Nacional de Enfermedades Respiratorias “Dr. E. Coni”; Argentina Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina Fil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina Fil: Previtali, M. Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Previtali, M. Andrea. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Ciencias Naturales; Argentina |
| description |
This study examines household pets as potential epidemiological links between environments contaminated with pathogenic leptospires and humans in Santa Fe, Argentina. The aims of our study were: (a) to characterize the habits and exposure to environmental sources of leptospirosis in the population of dogs and cats attending to municipal spay and neutering campaigns in Santa Fe, Argentina, (b) to assess the seroprevalence of anti-Leptospira antibodies in asymptomatic dogs and cats, (c) to evaluate factors that could increase seropositivity, and (d) to identify spatial clusters of seropositive dogs and cats in the capital city of Santa Fe. From May to November 2022, a cross-sectional serosurvey was conducted during municipal spaying/neutering campaigns. Eligible household dogs and cats were over 6 months old, apparently healthy, and not vaccinated against leptospirosis in the past 6 months. We used microagglutination test (MAT) to assess anti-Leptospira antibodies using a panel of 10 reference strains. We used generalized linear mixed effects models (GLMM) to examine individual and census tract-level risk factors for seropositivity, and local Moran’s I statistic for spatial clusters. Results showed higher leptospiral antibody prevalence in dogs (18.2 %) than cats (3.6 %, p = 0.002). Dogs with street access had higher likelihood of being seropositive (OR: 3.8, 95 % CI: 1.2; 11.9), and areas with chronic poverty showed an elevated risk of presenting seropositive animals (RR: 4.0, 95 % CI: 1.1; 14.4). Spatial analysis didn't reveal significant seropositivity clusters among census tracts. These findings shed light on widespread Leptospira seropositivity in pets in this endemic region. Understanding seroprevalence and risk factors can guide public and veterinary health strategies, emphasizing increased leptospirosis vaccination for dogs in vulnerable areas and promoting responsible pet care. |
| publishDate |
2024 |
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2024-08 2025-05-06T12:05:33Z 2025-05-06T12:05:33Z |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
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| url |
http://hdl.handle.net/20.500.12123/22166 https://www.sciencedirect.com/science/article/abs/pii/S0167587724001259 https://doi.org/10.1016/j.prevetmed.2024.106239 |
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eng |
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info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
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http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) |
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application/pdf |
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Santa Fé .......... (inhabited place) (World, South America, Argentina, Santa Fe) 1020035 |
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Elsevier |
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Elsevier |
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Preventive Veterinary Medicine 229 : 106239. (August 2024) reponame:INTA Digital (INTA) instname:Instituto Nacional de Tecnología Agropecuaria |
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