Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis

Autores
Rodrigues, Diego Lucas Neres; Costa, Francielly Morais Rodrigues da; Marques Da Silva, Wanderson; Aburjaile, Flavia; Azevedo, Vasco
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.
Instituto de Biotecnología
Fil: Rodrigues, Diego Lucas Neres. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil
Fil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil
Fil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Marques Da Silva, Wanderson. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aburjaile, Flavia. Universidade Federal de Minas Gerais. Veterinary School. Preventive Veterinary Medicine Department; Brasil
Fil: Azevedo, Vasco. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil
Fuente
Bacteria 1 (2) : 112-120 (June 2022)
Materia
Infection
Acinetobacter
Resistance to Antibiotics
Infección
Resistencia a los Antibióticos
Acinetobacter baumannii
Carbapenem
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
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spelling Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysisRodrigues, Diego Lucas NeresCosta, Francielly Morais Rodrigues daMarques Da Silva, WandersonAburjaile, FlaviaAzevedo, VascoInfectionAcinetobacterResistance to AntibioticsInfecciónResistencia a los AntibióticosAcinetobacter baumanniiCarbapenemInfections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.Instituto de BiotecnologíaFil: Rodrigues, Diego Lucas Neres. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; BrasilFil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; BrasilFil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Marques Da Silva, Wanderson. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Aburjaile, Flavia. Universidade Federal de Minas Gerais. Veterinary School. Preventive Veterinary Medicine Department; BrasilFil: Azevedo, Vasco. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; BrasilMDPI2022-08-22T12:33:05Z2022-08-22T12:33:05Z2022-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/12648https://www.mdpi.com/2674-1334/1/2/102674-1334https://doi.org/10.3390/bacteria1020010Bacteria 1 (2) : 112-120 (June 2022)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-29T13:45:41Zoai:localhost:20.500.12123/12648instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:45:41.946INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
title Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
spellingShingle Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
Rodrigues, Diego Lucas Neres
Infection
Acinetobacter
Resistance to Antibiotics
Infección
Resistencia a los Antibióticos
Acinetobacter baumannii
Carbapenem
title_short Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
title_full Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
title_fullStr Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
title_full_unstemmed Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
title_sort Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
dc.creator.none.fl_str_mv Rodrigues, Diego Lucas Neres
Costa, Francielly Morais Rodrigues da
Marques Da Silva, Wanderson
Aburjaile, Flavia
Azevedo, Vasco
author Rodrigues, Diego Lucas Neres
author_facet Rodrigues, Diego Lucas Neres
Costa, Francielly Morais Rodrigues da
Marques Da Silva, Wanderson
Aburjaile, Flavia
Azevedo, Vasco
author_role author
author2 Costa, Francielly Morais Rodrigues da
Marques Da Silva, Wanderson
Aburjaile, Flavia
Azevedo, Vasco
author2_role author
author
author
author
dc.subject.none.fl_str_mv Infection
Acinetobacter
Resistance to Antibiotics
Infección
Resistencia a los Antibióticos
Acinetobacter baumannii
Carbapenem
topic Infection
Acinetobacter
Resistance to Antibiotics
Infección
Resistencia a los Antibióticos
Acinetobacter baumannii
Carbapenem
dc.description.none.fl_txt_mv Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.
Instituto de Biotecnología
Fil: Rodrigues, Diego Lucas Neres. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil
Fil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil
Fil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Marques Da Silva, Wanderson. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aburjaile, Flavia. Universidade Federal de Minas Gerais. Veterinary School. Preventive Veterinary Medicine Department; Brasil
Fil: Azevedo, Vasco. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil
description Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-22T12:33:05Z
2022-08-22T12:33:05Z
2022-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/12648
https://www.mdpi.com/2674-1334/1/2/10
2674-1334
https://doi.org/10.3390/bacteria1020010
url http://hdl.handle.net/20.500.12123/12648
https://www.mdpi.com/2674-1334/1/2/10
https://doi.org/10.3390/bacteria1020010
identifier_str_mv 2674-1334
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Bacteria 1 (2) : 112-120 (June 2022)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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