Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina

Autores
Sagua, Maria Delia; Lúquez, Carolina; Bianco, María Isabel; Fernandez, Rafael Alfredo
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Infant botulism is the most common form of human botulism; however, its transmission has not been completely explained yet. Some of the most recognized potential sources of Clostridium botulinum spores are the soil, dust, honey and medicinal herbs. In Argentina, 456 cases of infant botulism were reported between 1982 and 2007. C. botulinum type A was identified in 455 of these cases whereas type B was identified in just one case. However, in Argentina, types A, B, E, F, G, and Af have been isolated from environmental sources. It is not clearly known if strains isolated from infant botulism cases have different characteristics from strains isolated from other sources. During this study, 46 C. botulinum strains isolated from infant botulism cases and from environmental sources were typified according to phenotypic characteristics. Biochemical tests, antimicrobial activity, and haemagglutinin-negative botulinum neurotoxin production showed uniformity among all these strains. Despite the variability observed in the botulinum neurotoxin's binding to cellular receptors, no correlation was found between these patterns and the source of the botulinum neurotoxin. However, an apparent geographical clustering was observed, since strains isolated from Argentina had similar characteristics to those isolated from Italy and Japan, but different to those isolated from the United States.
Fil: Sagua, Maria Delia. Universidad Nacional de Cuyo; Argentina
Fil: Lúquez, Carolina. Universidad Nacional de Cuyo; Argentina
Fil: Bianco, María Isabel. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina
Materia
C. botulinum
infant botulism
soil
Argentina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/38106
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in ArgentinaSagua, Maria DeliaLúquez, CarolinaBianco, María IsabelFernandez, Rafael AlfredoC. botulinuminfant botulismsoilArgentinahttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Infant botulism is the most common form of human botulism; however, its transmission has not been completely explained yet. Some of the most recognized potential sources of Clostridium botulinum spores are the soil, dust, honey and medicinal herbs. In Argentina, 456 cases of infant botulism were reported between 1982 and 2007. C. botulinum type A was identified in 455 of these cases whereas type B was identified in just one case. However, in Argentina, types A, B, E, F, G, and Af have been isolated from environmental sources. It is not clearly known if strains isolated from infant botulism cases have different characteristics from strains isolated from other sources. During this study, 46 C. botulinum strains isolated from infant botulism cases and from environmental sources were typified according to phenotypic characteristics. Biochemical tests, antimicrobial activity, and haemagglutinin-negative botulinum neurotoxin production showed uniformity among all these strains. Despite the variability observed in the botulinum neurotoxin's binding to cellular receptors, no correlation was found between these patterns and the source of the botulinum neurotoxin. However, an apparent geographical clustering was observed, since strains isolated from Argentina had similar characteristics to those isolated from Italy and Japan, but different to those isolated from the United States.Fil: Sagua, Maria Delia. Universidad Nacional de Cuyo; ArgentinaFil: Lúquez, Carolina. Universidad Nacional de Cuyo; ArgentinaFil: Bianco, María Isabel. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; ArgentinaAsociación Argentina de Microbiología2009-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/38106Sagua, Maria Delia; Lúquez, Carolina; Bianco, María Isabel; Fernandez, Rafael Alfredo; Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina; Asociación Argentina de Microbiología; Revista Argentina de Microbiología; 41; 3; 6-2009; 141-1470325-75410325-7541CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.scielo.org.ar/pdf/ram/v41n3/v41n3a04.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:25:40Zoai:ri.conicet.gov.ar:11336/38106instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:25:40.489CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
title Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
spellingShingle Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
Sagua, Maria Delia
C. botulinum
infant botulism
soil
Argentina
title_short Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
title_full Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
title_fullStr Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
title_full_unstemmed Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
title_sort Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina
dc.creator.none.fl_str_mv Sagua, Maria Delia
Lúquez, Carolina
Bianco, María Isabel
Fernandez, Rafael Alfredo
author Sagua, Maria Delia
author_facet Sagua, Maria Delia
Lúquez, Carolina
Bianco, María Isabel
Fernandez, Rafael Alfredo
author_role author
author2 Lúquez, Carolina
Bianco, María Isabel
Fernandez, Rafael Alfredo
author2_role author
author
author
dc.subject.none.fl_str_mv C. botulinum
infant botulism
soil
Argentina
topic C. botulinum
infant botulism
soil
Argentina
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Infant botulism is the most common form of human botulism; however, its transmission has not been completely explained yet. Some of the most recognized potential sources of Clostridium botulinum spores are the soil, dust, honey and medicinal herbs. In Argentina, 456 cases of infant botulism were reported between 1982 and 2007. C. botulinum type A was identified in 455 of these cases whereas type B was identified in just one case. However, in Argentina, types A, B, E, F, G, and Af have been isolated from environmental sources. It is not clearly known if strains isolated from infant botulism cases have different characteristics from strains isolated from other sources. During this study, 46 C. botulinum strains isolated from infant botulism cases and from environmental sources were typified according to phenotypic characteristics. Biochemical tests, antimicrobial activity, and haemagglutinin-negative botulinum neurotoxin production showed uniformity among all these strains. Despite the variability observed in the botulinum neurotoxin's binding to cellular receptors, no correlation was found between these patterns and the source of the botulinum neurotoxin. However, an apparent geographical clustering was observed, since strains isolated from Argentina had similar characteristics to those isolated from Italy and Japan, but different to those isolated from the United States.
Fil: Sagua, Maria Delia. Universidad Nacional de Cuyo; Argentina
Fil: Lúquez, Carolina. Universidad Nacional de Cuyo; Argentina
Fil: Bianco, María Isabel. Universidad Nacional de Cuyo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina
description Infant botulism is the most common form of human botulism; however, its transmission has not been completely explained yet. Some of the most recognized potential sources of Clostridium botulinum spores are the soil, dust, honey and medicinal herbs. In Argentina, 456 cases of infant botulism were reported between 1982 and 2007. C. botulinum type A was identified in 455 of these cases whereas type B was identified in just one case. However, in Argentina, types A, B, E, F, G, and Af have been isolated from environmental sources. It is not clearly known if strains isolated from infant botulism cases have different characteristics from strains isolated from other sources. During this study, 46 C. botulinum strains isolated from infant botulism cases and from environmental sources were typified according to phenotypic characteristics. Biochemical tests, antimicrobial activity, and haemagglutinin-negative botulinum neurotoxin production showed uniformity among all these strains. Despite the variability observed in the botulinum neurotoxin's binding to cellular receptors, no correlation was found between these patterns and the source of the botulinum neurotoxin. However, an apparent geographical clustering was observed, since strains isolated from Argentina had similar characteristics to those isolated from Italy and Japan, but different to those isolated from the United States.
publishDate 2009
dc.date.none.fl_str_mv 2009-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/38106
Sagua, Maria Delia; Lúquez, Carolina; Bianco, María Isabel; Fernandez, Rafael Alfredo; Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina; Asociación Argentina de Microbiología; Revista Argentina de Microbiología; 41; 3; 6-2009; 141-147
0325-7541
0325-7541
CONICET Digital
CONICET
url http://hdl.handle.net/11336/38106
identifier_str_mv Sagua, Maria Delia; Lúquez, Carolina; Bianco, María Isabel; Fernandez, Rafael Alfredo; Phenotypic characterization of Clostridium botulinum strains isolated from infant botulism cases in Argentina; Asociación Argentina de Microbiología; Revista Argentina de Microbiología; 41; 3; 6-2009; 141-147
0325-7541
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.scielo.org.ar/pdf/ram/v41n3/v41n3a04.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Asociación Argentina de Microbiología
publisher.none.fl_str_mv Asociación Argentina de Microbiología
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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