Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei

Autores
Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; Bianco, Maria Isabel
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease.
Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina;
Fil: Carbone, María Laura.
Fil: Sánchez, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Limnología; Argentina;
Fil: Pareja, Virtudes.
Fil: de Jong, Laura Irene Teresita.
Fil: Bianco, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;
Materia
BOTULISM
INFANT BOTULISM
TOXIN FORMATION
INHIBITION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/1690

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spelling Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracaseiFernandez, Rafael AlfredoCarbone, María LauraSánchez, María LauraPareja, Virtudesde Jong, Laura Irene TeresitaBianco, Maria IsabelBOTULISMINFANT BOTULISMTOXIN FORMATIONINHIBITIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease.Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina;Fil: Carbone, María Laura.Fil: Sánchez, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Limnología; Argentina;Fil: Pareja, Virtudes.Fil: de Jong, Laura Irene Teresita.Fil: Bianco, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;Alkhaer Publications2013-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/1690Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; et al.; Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei; Alkhaer Publications; International Journal of Sciences; 2; 10; 10-2013; 87-932305-3925enginfo:eu-repo/semantics/altIdentifier/url/http://www.ijsciences.com/pub/article/317info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:39:19Zoai:ri.conicet.gov.ar:11336/1690instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:39:19.837CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
title Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
spellingShingle Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
Fernandez, Rafael Alfredo
BOTULISM
INFANT BOTULISM
TOXIN FORMATION
INHIBITION
title_short Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
title_full Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
title_fullStr Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
title_full_unstemmed Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
title_sort Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
dc.creator.none.fl_str_mv Fernandez, Rafael Alfredo
Carbone, María Laura
Sánchez, María Laura
Pareja, Virtudes
de Jong, Laura Irene Teresita
Bianco, Maria Isabel
author Fernandez, Rafael Alfredo
author_facet Fernandez, Rafael Alfredo
Carbone, María Laura
Sánchez, María Laura
Pareja, Virtudes
de Jong, Laura Irene Teresita
Bianco, Maria Isabel
author_role author
author2 Carbone, María Laura
Sánchez, María Laura
Pareja, Virtudes
de Jong, Laura Irene Teresita
Bianco, Maria Isabel
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv BOTULISM
INFANT BOTULISM
TOXIN FORMATION
INHIBITION
topic BOTULISM
INFANT BOTULISM
TOXIN FORMATION
INHIBITION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease.
Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina;
Fil: Carbone, María Laura.
Fil: Sánchez, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Limnología; Argentina;
Fil: Pareja, Virtudes.
Fil: de Jong, Laura Irene Teresita.
Fil: Bianco, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;
description Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease.
publishDate 2013
dc.date.none.fl_str_mv 2013-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/1690
Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; et al.; Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei; Alkhaer Publications; International Journal of Sciences; 2; 10; 10-2013; 87-93
2305-3925
url http://hdl.handle.net/11336/1690
identifier_str_mv Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; et al.; Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei; Alkhaer Publications; International Journal of Sciences; 2; 10; 10-2013; 87-93
2305-3925
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ijsciences.com/pub/article/317
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Alkhaer Publications
publisher.none.fl_str_mv Alkhaer Publications
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432