Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei
- Autores
- Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; Bianco, Maria Isabel
- Año de publicación
- 2013
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease.
Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina;
Fil: Carbone, María Laura.
Fil: Sánchez, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Limnología; Argentina;
Fil: Pareja, Virtudes.
Fil: de Jong, Laura Irene Teresita.
Fil: Bianco, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología; - Materia
-
BOTULISM
INFANT BOTULISM
TOXIN FORMATION
INHIBITION - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/1690
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Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracaseiFernandez, Rafael AlfredoCarbone, María LauraSánchez, María LauraPareja, Virtudesde Jong, Laura Irene TeresitaBianco, Maria IsabelBOTULISMINFANT BOTULISMTOXIN FORMATIONINHIBITIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease.Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina;Fil: Carbone, María Laura.Fil: Sánchez, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Limnología; Argentina;Fil: Pareja, Virtudes.Fil: de Jong, Laura Irene Teresita.Fil: Bianco, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología;Alkhaer Publications2013-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/1690Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; et al.; Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei; Alkhaer Publications; International Journal of Sciences; 2; 10; 10-2013; 87-932305-3925enginfo:eu-repo/semantics/altIdentifier/url/http://www.ijsciences.com/pub/article/317info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:39:19Zoai:ri.conicet.gov.ar:11336/1690instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:39:19.837CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
title |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
spellingShingle |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei Fernandez, Rafael Alfredo BOTULISM INFANT BOTULISM TOXIN FORMATION INHIBITION |
title_short |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
title_full |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
title_fullStr |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
title_full_unstemmed |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
title_sort |
Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei |
dc.creator.none.fl_str_mv |
Fernandez, Rafael Alfredo Carbone, María Laura Sánchez, María Laura Pareja, Virtudes de Jong, Laura Irene Teresita Bianco, Maria Isabel |
author |
Fernandez, Rafael Alfredo |
author_facet |
Fernandez, Rafael Alfredo Carbone, María Laura Sánchez, María Laura Pareja, Virtudes de Jong, Laura Irene Teresita Bianco, Maria Isabel |
author_role |
author |
author2 |
Carbone, María Laura Sánchez, María Laura Pareja, Virtudes de Jong, Laura Irene Teresita Bianco, Maria Isabel |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
BOTULISM INFANT BOTULISM TOXIN FORMATION INHIBITION |
topic |
BOTULISM INFANT BOTULISM TOXIN FORMATION INHIBITION |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease. Fil: Fernandez, Rafael Alfredo. Universidad Nacional de Cuyo; Argentina; Fil: Carbone, María Laura. Fil: Sánchez, María Laura. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Limnología; Argentina; Fil: Pareja, Virtudes. Fil: de Jong, Laura Irene Teresita. Fil: Bianco, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ciencia y Tecnología; |
description |
Infant botulism is an intestinal toxic-infection affecting infants younger than one year of age, and currently in some country is the most important form of human botulism by its frequency of occurrence. It is a rare neuroparalytic disease, but potentially fatal, especially if it is not early diagnosed and properly treated. It is caused by botulinum neurotoxins produced by species of Clostridium, principally C. botulinum. C. botulinum spores are widely distributed in nature, and its most common habitat and natural reservoir is the soil, the main source of contamination for the different forms of botulism. C. botulinum spores have been identified in some foods, such as honey, corn syrup, infant formula and in some medicinal plants. Considering the difficulty to prevent the swallowing of spores, is particularly relevant have adequate arrangements to interfere with colonization and/or toxin formation of C. botulinum in the intestine. Different probiotics have been demonstrated utility against several intestinal pathogens. So, we studied and demonstrated the interference of Lactobacillus paracasei subsp. paracasei on the growth and toxin formation of one strain of C. botulinum type A. Therefore, administering probiotics to infants, perhaps from birth, would be effective in preventing or treating the disease. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/1690 Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; et al.; Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei; Alkhaer Publications; International Journal of Sciences; 2; 10; 10-2013; 87-93 2305-3925 |
url |
http://hdl.handle.net/11336/1690 |
identifier_str_mv |
Fernandez, Rafael Alfredo; Carbone, María Laura; Sánchez, María Laura; Pareja, Virtudes; de Jong, Laura Irene Teresita; et al.; Interference of the Developing and Toxin Production of Clostridium botulinum by Lactobacillus paracasei subspecies paracasei; Alkhaer Publications; International Journal of Sciences; 2; 10; 10-2013; 87-93 2305-3925 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.ijsciences.com/pub/article/317 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Alkhaer Publications |
publisher.none.fl_str_mv |
Alkhaer Publications |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614418051104768 |
score |
13.070432 |