A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina

Autores
Becaria Coquet, Julia; Muñoz, Sonia Edith; Diaz, Maria del Pilar
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Colorectal cancer (CRC) is the third most incident cancer in Argentina and diet is widely recognized for being associatedwith CRC. The objective of this work was to construct a methodological framework to quantitatively assess systematicerrors in a case-control study, carried out in adult population of Córdoba province (2010-2016).ACRC case-control study (n=490, 161/329 cases/controls) was conducted. Confounding was analyzed applying regression models approach forobserved and unobserved variables. Selection bias was investigated utilizing deterministic scenarios, assigning a priori participationprobabilities. Information bias, derived from missing data in covariates, was handled applying multiple imputation by chained equations (MICE),considering the missing at random mechanism.Confounding effects of sex and socioeconomic status were found. In respect of selection bias, differences regarding conventional estimates werenegligible. MI approach showed a promoting effect of the South Cone dietary pattern. Significant associations with sex, BMI, family history ofCRC and socioeconomic status were observed.
Fil: Becaria Coquet, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Histología, Embriología y Genética; Argentina
Fil: Muñoz, Sonia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Histología, Embriología y Genética; Argentina
Fil: Diaz, Maria del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Nutrición; Argentina
Materia
SENSITIVITY ANALYSIS
CASE CONTROL STUDY
DIETARY PATTERN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/65108
Acceder
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network_name_str CONICET Digital (CONICET)
spelling A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in ArgentinaBecaria Coquet, JuliaMuñoz, Sonia EdithDiaz, Maria del PilarSENSITIVITY ANALYSISCASE CONTROL STUDYDIETARY PATTERNhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Colorectal cancer (CRC) is the third most incident cancer in Argentina and diet is widely recognized for being associatedwith CRC. The objective of this work was to construct a methodological framework to quantitatively assess systematicerrors in a case-control study, carried out in adult population of Córdoba province (2010-2016).ACRC case-control study (n=490, 161/329 cases/controls) was conducted. Confounding was analyzed applying regression models approach forobserved and unobserved variables. Selection bias was investigated utilizing deterministic scenarios, assigning a priori participationprobabilities. Information bias, derived from missing data in covariates, was handled applying multiple imputation by chained equations (MICE),considering the missing at random mechanism.Confounding effects of sex and socioeconomic status were found. In respect of selection bias, differences regarding conventional estimates werenegligible. MI approach showed a promoting effect of the South Cone dietary pattern. Significant associations with sex, BMI, family history ofCRC and socioeconomic status were observed.Fil: Becaria Coquet, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Histología, Embriología y Genética; ArgentinaFil: Muñoz, Sonia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Histología, Embriología y Genética; ArgentinaFil: Diaz, Maria del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Nutrición; ArgentinaMedical Council of India2017-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/65108Becaria Coquet, Julia; Muñoz, Sonia Edith; Diaz, Maria del Pilar; A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina; Medical Council of India; Indian Journal of Applied Research; 7; 12; 12-2017; 657-6632249-555xCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://wwjournals.com/index.php/ijar/article/view/7114info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:09:10Zoai:ri.conicet.gov.ar:11336/65108instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:09:11.043CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
title A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
spellingShingle A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
Becaria Coquet, Julia
SENSITIVITY ANALYSIS
CASE CONTROL STUDY
DIETARY PATTERN
title_short A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
title_full A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
title_fullStr A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
title_full_unstemmed A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
title_sort A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina
dc.creator.none.fl_str_mv Becaria Coquet, Julia
Muñoz, Sonia Edith
Diaz, Maria del Pilar
author Becaria Coquet, Julia
author_facet Becaria Coquet, Julia
Muñoz, Sonia Edith
Diaz, Maria del Pilar
author_role author
author2 Muñoz, Sonia Edith
Diaz, Maria del Pilar
author2_role author
author
dc.subject.none.fl_str_mv SENSITIVITY ANALYSIS
CASE CONTROL STUDY
DIETARY PATTERN
topic SENSITIVITY ANALYSIS
CASE CONTROL STUDY
DIETARY PATTERN
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Colorectal cancer (CRC) is the third most incident cancer in Argentina and diet is widely recognized for being associatedwith CRC. The objective of this work was to construct a methodological framework to quantitatively assess systematicerrors in a case-control study, carried out in adult population of Córdoba province (2010-2016).ACRC case-control study (n=490, 161/329 cases/controls) was conducted. Confounding was analyzed applying regression models approach forobserved and unobserved variables. Selection bias was investigated utilizing deterministic scenarios, assigning a priori participationprobabilities. Information bias, derived from missing data in covariates, was handled applying multiple imputation by chained equations (MICE),considering the missing at random mechanism.Confounding effects of sex and socioeconomic status were found. In respect of selection bias, differences regarding conventional estimates werenegligible. MI approach showed a promoting effect of the South Cone dietary pattern. Significant associations with sex, BMI, family history ofCRC and socioeconomic status were observed.
Fil: Becaria Coquet, Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Histología, Embriología y Genética; Argentina
Fil: Muñoz, Sonia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Histología, Embriología y Genética; Argentina
Fil: Diaz, Maria del Pilar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Nutrición; Argentina
description Colorectal cancer (CRC) is the third most incident cancer in Argentina and diet is widely recognized for being associatedwith CRC. The objective of this work was to construct a methodological framework to quantitatively assess systematicerrors in a case-control study, carried out in adult population of Córdoba province (2010-2016).ACRC case-control study (n=490, 161/329 cases/controls) was conducted. Confounding was analyzed applying regression models approach forobserved and unobserved variables. Selection bias was investigated utilizing deterministic scenarios, assigning a priori participationprobabilities. Information bias, derived from missing data in covariates, was handled applying multiple imputation by chained equations (MICE),considering the missing at random mechanism.Confounding effects of sex and socioeconomic status were found. In respect of selection bias, differences regarding conventional estimates werenegligible. MI approach showed a promoting effect of the South Cone dietary pattern. Significant associations with sex, BMI, family history ofCRC and socioeconomic status were observed.
publishDate 2017
dc.date.none.fl_str_mv 2017-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/65108
Becaria Coquet, Julia; Muñoz, Sonia Edith; Diaz, Maria del Pilar; A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina; Medical Council of India; Indian Journal of Applied Research; 7; 12; 12-2017; 657-663
2249-555x
CONICET Digital
CONICET
url http://hdl.handle.net/11336/65108
identifier_str_mv Becaria Coquet, Julia; Muñoz, Sonia Edith; Diaz, Maria del Pilar; A framework to address potential bias in colorectal cancer: Its implementation on a nutritional epidemiologic study in Argentina; Medical Council of India; Indian Journal of Applied Research; 7; 12; 12-2017; 657-663
2249-555x
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://wwjournals.com/index.php/ijar/article/view/7114
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Medical Council of India
publisher.none.fl_str_mv Medical Council of India
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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