Structure-activity relationship of berberine and derivatives acting as antifungal compounds

Autores
Enriz, Ricardo Daniel; Freile, Monica Liliana
Año de publicación
2006
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A structure-activity relationship study of berberine and structurally related compounds is reported. Berberine, was chemically modified in order to obtain canadine and oxyberberine. The in vitro evaluation of antifungal activity of berberine, canadine, oxyberberine, liriodenine, o-methyl-mostachatoline and other four derivatives is also reported here. Our results allow us to determine the minimal structural requirements to produce the antifungal response and can provide a guide for the design of new compounds with these properties.
Fil: Enriz, Ricardo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
Fil: Freile, Monica Liliana. Universidad Nacional de la Patagonia "San Juan Bosco"; Argentina
Materia
Berberine
Antifungal activity
Structural requirements
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/138703
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Structure-activity relationship of berberine and derivatives acting as antifungal compoundsEnriz, Ricardo DanielFreile, Monica LilianaBerberineAntifungal activityStructural requirementshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A structure-activity relationship study of berberine and structurally related compounds is reported. Berberine, was chemically modified in order to obtain canadine and oxyberberine. The in vitro evaluation of antifungal activity of berberine, canadine, oxyberberine, liriodenine, o-methyl-mostachatoline and other four derivatives is also reported here. Our results allow us to determine the minimal structural requirements to produce the antifungal response and can provide a guide for the design of new compounds with these properties.Fil: Enriz, Ricardo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; ArgentinaFil: Freile, Monica Liliana. Universidad Nacional de la Patagonia "San Juan Bosco"; ArgentinaAsociación Química Argentina2006-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/138703Enriz, Ricardo Daniel; Freile, Monica Liliana; Structure-activity relationship of berberine and derivatives acting as antifungal compounds; Asociación Química Argentina; Journal of the Argentine Chemical Society; 94; 1-3; 6-2006; 113-1190365-0375CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/index.php/volumenes-publicados/47-vol-94-1-3-january-june-2006info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:57:18Zoai:ri.conicet.gov.ar:11336/138703instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:19.211CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Structure-activity relationship of berberine and derivatives acting as antifungal compounds
title Structure-activity relationship of berberine and derivatives acting as antifungal compounds
spellingShingle Structure-activity relationship of berberine and derivatives acting as antifungal compounds
Enriz, Ricardo Daniel
Berberine
Antifungal activity
Structural requirements
title_short Structure-activity relationship of berberine and derivatives acting as antifungal compounds
title_full Structure-activity relationship of berberine and derivatives acting as antifungal compounds
title_fullStr Structure-activity relationship of berberine and derivatives acting as antifungal compounds
title_full_unstemmed Structure-activity relationship of berberine and derivatives acting as antifungal compounds
title_sort Structure-activity relationship of berberine and derivatives acting as antifungal compounds
dc.creator.none.fl_str_mv Enriz, Ricardo Daniel
Freile, Monica Liliana
author Enriz, Ricardo Daniel
author_facet Enriz, Ricardo Daniel
Freile, Monica Liliana
author_role author
author2 Freile, Monica Liliana
author2_role author
dc.subject.none.fl_str_mv Berberine
Antifungal activity
Structural requirements
topic Berberine
Antifungal activity
Structural requirements
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A structure-activity relationship study of berberine and structurally related compounds is reported. Berberine, was chemically modified in order to obtain canadine and oxyberberine. The in vitro evaluation of antifungal activity of berberine, canadine, oxyberberine, liriodenine, o-methyl-mostachatoline and other four derivatives is also reported here. Our results allow us to determine the minimal structural requirements to produce the antifungal response and can provide a guide for the design of new compounds with these properties.
Fil: Enriz, Ricardo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
Fil: Freile, Monica Liliana. Universidad Nacional de la Patagonia "San Juan Bosco"; Argentina
description A structure-activity relationship study of berberine and structurally related compounds is reported. Berberine, was chemically modified in order to obtain canadine and oxyberberine. The in vitro evaluation of antifungal activity of berberine, canadine, oxyberberine, liriodenine, o-methyl-mostachatoline and other four derivatives is also reported here. Our results allow us to determine the minimal structural requirements to produce the antifungal response and can provide a guide for the design of new compounds with these properties.
publishDate 2006
dc.date.none.fl_str_mv 2006-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/138703
Enriz, Ricardo Daniel; Freile, Monica Liliana; Structure-activity relationship of berberine and derivatives acting as antifungal compounds; Asociación Química Argentina; Journal of the Argentine Chemical Society; 94; 1-3; 6-2006; 113-119
0365-0375
CONICET Digital
CONICET
url http://hdl.handle.net/11336/138703
identifier_str_mv Enriz, Ricardo Daniel; Freile, Monica Liliana; Structure-activity relationship of berberine and derivatives acting as antifungal compounds; Asociación Química Argentina; Journal of the Argentine Chemical Society; 94; 1-3; 6-2006; 113-119
0365-0375
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.aqa.org.ar/index.php/volumenes-publicados/47-vol-94-1-3-january-june-2006
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Asociación Química Argentina
publisher.none.fl_str_mv Asociación Química Argentina
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613715860652032
score 13.070432

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