Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)

Autores
Di Marzio, Walter Dario; Curieses, Silvana Patricia; Alberdi, José Luis; Sáenz, María Elena
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
To understand and assess the effects of nanoparticles (NPs) on the environment, should be well established quantitatively the concentration-response relationships. Also relate the potential effects on selected variables of response with the exposure to sub-lethal levels of NPs. In this work, we describe the ecotoxicological evaluation of negative and positive coated silica NPs (Si-Nps) on coelomic cells from Eisenia fetida. The cytotoxicity of earthworm coelomocytes, expressed as LC50-1hour, was equal to 73.94 and 116.93 μg/mL for positive and negative Si-NPs, respectively. Genotoxicity were determined on the basis that the Si-NPs promote the generation of reactive oxygen species (ROS) once added on cell membranes, or entered in cells. In this case both types of NPs were genotoxics even at the lowest tested concentration equal to 1 μg/mL.
Fil: Di Marzio, Walter Dario. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Curieses, Silvana Patricia. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Alberdi, José Luis. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina
Fil: Sáenz, María Elena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina
Materia
Eisenia fetida
Silica nanoparticles
Genotoxicity
Cytotoxicity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/177286
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)Di Marzio, Walter DarioCurieses, Silvana PatriciaAlberdi, José LuisSáenz, María ElenaEisenia fetidaSilica nanoparticlesGenotoxicityCytotoxicityhttps://purl.org/becyt/ford/1.5https://purl.org/becyt/ford/1To understand and assess the effects of nanoparticles (NPs) on the environment, should be well established quantitatively the concentration-response relationships. Also relate the potential effects on selected variables of response with the exposure to sub-lethal levels of NPs. In this work, we describe the ecotoxicological evaluation of negative and positive coated silica NPs (Si-Nps) on coelomic cells from Eisenia fetida. The cytotoxicity of earthworm coelomocytes, expressed as LC50-1hour, was equal to 73.94 and 116.93 μg/mL for positive and negative Si-NPs, respectively. Genotoxicity were determined on the basis that the Si-NPs promote the generation of reactive oxygen species (ROS) once added on cell membranes, or entered in cells. In this case both types of NPs were genotoxics even at the lowest tested concentration equal to 1 μg/mL.Fil: Di Marzio, Walter Dario. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Curieses, Silvana Patricia. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Alberdi, José Luis. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; ArgentinaFil: Sáenz, María Elena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; ArgentinaScholars Direct2018-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/177286Di Marzio, Walter Dario; Curieses, Silvana Patricia; Alberdi, José Luis; Sáenz, María Elena; Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida); Scholars Direct; Advances in Environmental Studies; 2; 1; 7-2018; 74-810938-3158CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://scholars.direct/Articles/environmental-studies/aes-2-010.php?jid=environmental-studiesinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:07:09Zoai:ri.conicet.gov.ar:11336/177286instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:07:09.862CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
title Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
spellingShingle Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
Di Marzio, Walter Dario
Eisenia fetida
Silica nanoparticles
Genotoxicity
Cytotoxicity
title_short Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
title_full Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
title_fullStr Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
title_full_unstemmed Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
title_sort Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida)
dc.creator.none.fl_str_mv Di Marzio, Walter Dario
Curieses, Silvana Patricia
Alberdi, José Luis
Sáenz, María Elena
author Di Marzio, Walter Dario
author_facet Di Marzio, Walter Dario
Curieses, Silvana Patricia
Alberdi, José Luis
Sáenz, María Elena
author_role author
author2 Curieses, Silvana Patricia
Alberdi, José Luis
Sáenz, María Elena
author2_role author
author
author
dc.subject.none.fl_str_mv Eisenia fetida
Silica nanoparticles
Genotoxicity
Cytotoxicity
topic Eisenia fetida
Silica nanoparticles
Genotoxicity
Cytotoxicity
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.5
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv To understand and assess the effects of nanoparticles (NPs) on the environment, should be well established quantitatively the concentration-response relationships. Also relate the potential effects on selected variables of response with the exposure to sub-lethal levels of NPs. In this work, we describe the ecotoxicological evaluation of negative and positive coated silica NPs (Si-Nps) on coelomic cells from Eisenia fetida. The cytotoxicity of earthworm coelomocytes, expressed as LC50-1hour, was equal to 73.94 and 116.93 μg/mL for positive and negative Si-NPs, respectively. Genotoxicity were determined on the basis that the Si-NPs promote the generation of reactive oxygen species (ROS) once added on cell membranes, or entered in cells. In this case both types of NPs were genotoxics even at the lowest tested concentration equal to 1 μg/mL.
Fil: Di Marzio, Walter Dario. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Curieses, Silvana Patricia. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Alberdi, José Luis. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina
Fil: Sáenz, María Elena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Investigación en Ecotoxicología; Argentina
description To understand and assess the effects of nanoparticles (NPs) on the environment, should be well established quantitatively the concentration-response relationships. Also relate the potential effects on selected variables of response with the exposure to sub-lethal levels of NPs. In this work, we describe the ecotoxicological evaluation of negative and positive coated silica NPs (Si-Nps) on coelomic cells from Eisenia fetida. The cytotoxicity of earthworm coelomocytes, expressed as LC50-1hour, was equal to 73.94 and 116.93 μg/mL for positive and negative Si-NPs, respectively. Genotoxicity were determined on the basis that the Si-NPs promote the generation of reactive oxygen species (ROS) once added on cell membranes, or entered in cells. In this case both types of NPs were genotoxics even at the lowest tested concentration equal to 1 μg/mL.
publishDate 2018
dc.date.none.fl_str_mv 2018-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/177286
Di Marzio, Walter Dario; Curieses, Silvana Patricia; Alberdi, José Luis; Sáenz, María Elena; Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida); Scholars Direct; Advances in Environmental Studies; 2; 1; 7-2018; 74-81
0938-3158
CONICET Digital
CONICET
url http://hdl.handle.net/11336/177286
identifier_str_mv Di Marzio, Walter Dario; Curieses, Silvana Patricia; Alberdi, José Luis; Sáenz, María Elena; Cyto and genotoxicity of positive and negative coated Silica nano particles on Celomocytes of earthworms Eisenia fetida (Oligocheta, Annelida); Scholars Direct; Advances in Environmental Studies; 2; 1; 7-2018; 74-81
0938-3158
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://scholars.direct/Articles/environmental-studies/aes-2-010.php?jid=environmental-studies
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Scholars Direct
publisher.none.fl_str_mv Scholars Direct
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269991854931968
score 13.13397

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