Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles

Autores
Stroppa, Maria Mercedes; Carriazo, Carlota; Gerez, Nelia Martha; Garcia, Beatriz Alicia
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Triatoma infestans, the main vector of Chagas disease, is a blood-sucking insect. Flight dispersal of adults is the most important mechanism for reinfestation of houses after insecticide spraying. Flight muscles have two glycerol-3-phosphate dehydrogenase (GPDH) isoforms: GPDH-1 is involved in flight metabolism and GPDH-2 provides lipid precursors. In this study, we explored the profile of GPDH expression in females and males adult flight muscles under light/dark cycle, constant light, and constant dark conditions. Under constant dark conditions, GPDH-1 flight muscles of T. infestans showed a rhythmic pattern of transcription synchronous with a rhythmic profile of activity suggesting regulation by the endogenous circadian clock. Otherwise, the GPDH-2 expression analysis showed no regulation by the endogenous clock, but showed that an external factor, such as the dark/light period, was necessary for synchronization of GPDH-2 transcription and activity.
Fil: Stroppa, Maria Mercedes. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Carriazo, Carlota. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Gerez, Nelia Martha. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Garcia, Beatriz Alicia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Materia
Triatoma
Chagas
Glycerol-3-Phosphate Dehydrogenase
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/11403
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight musclesStroppa, Maria MercedesCarriazo, CarlotaGerez, Nelia MarthaGarcia, Beatriz AliciaTriatomaChagasGlycerol-3-Phosphate Dehydrogenasehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Triatoma infestans, the main vector of Chagas disease, is a blood-sucking insect. Flight dispersal of adults is the most important mechanism for reinfestation of houses after insecticide spraying. Flight muscles have two glycerol-3-phosphate dehydrogenase (GPDH) isoforms: GPDH-1 is involved in flight metabolism and GPDH-2 provides lipid precursors. In this study, we explored the profile of GPDH expression in females and males adult flight muscles under light/dark cycle, constant light, and constant dark conditions. Under constant dark conditions, GPDH-1 flight muscles of T. infestans showed a rhythmic pattern of transcription synchronous with a rhythmic profile of activity suggesting regulation by the endogenous circadian clock. Otherwise, the GPDH-2 expression analysis showed no regulation by the endogenous clock, but showed that an external factor, such as the dark/light period, was necessary for synchronization of GPDH-2 transcription and activity.Fil: Stroppa, Maria Mercedes. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaFil: Carriazo, Carlota. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaFil: Gerez, Nelia Martha. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaFil: Garcia, Beatriz Alicia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; ArgentinaAmerican Society Of Tropical Medicine And Hygiene2014-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/11403Stroppa, Maria Mercedes; Carriazo, Carlota; Gerez, Nelia Martha; Garcia, Beatriz Alicia; Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles; American Society Of Tropical Medicine And Hygiene; American Journal Of Tropical Medicine And Hygiene; 91; 2; 7-2014; 399-4050002-9637enginfo:eu-repo/semantics/altIdentifier/doi/10.4269/ajtmh.13-0556info:eu-repo/semantics/altIdentifier/url/http://www.ajtmh.org/content/91/2/399info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125269/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:06:46Zoai:ri.conicet.gov.ar:11336/11403instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:06:46.429CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
title Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
spellingShingle Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
Stroppa, Maria Mercedes
Triatoma
Chagas
Glycerol-3-Phosphate Dehydrogenase
title_short Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
title_full Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
title_fullStr Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
title_full_unstemmed Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
title_sort Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles
dc.creator.none.fl_str_mv Stroppa, Maria Mercedes
Carriazo, Carlota
Gerez, Nelia Martha
Garcia, Beatriz Alicia
author Stroppa, Maria Mercedes
author_facet Stroppa, Maria Mercedes
Carriazo, Carlota
Gerez, Nelia Martha
Garcia, Beatriz Alicia
author_role author
author2 Carriazo, Carlota
Gerez, Nelia Martha
Garcia, Beatriz Alicia
author2_role author
author
author
dc.subject.none.fl_str_mv Triatoma
Chagas
Glycerol-3-Phosphate Dehydrogenase
topic Triatoma
Chagas
Glycerol-3-Phosphate Dehydrogenase
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Triatoma infestans, the main vector of Chagas disease, is a blood-sucking insect. Flight dispersal of adults is the most important mechanism for reinfestation of houses after insecticide spraying. Flight muscles have two glycerol-3-phosphate dehydrogenase (GPDH) isoforms: GPDH-1 is involved in flight metabolism and GPDH-2 provides lipid precursors. In this study, we explored the profile of GPDH expression in females and males adult flight muscles under light/dark cycle, constant light, and constant dark conditions. Under constant dark conditions, GPDH-1 flight muscles of T. infestans showed a rhythmic pattern of transcription synchronous with a rhythmic profile of activity suggesting regulation by the endogenous circadian clock. Otherwise, the GPDH-2 expression analysis showed no regulation by the endogenous clock, but showed that an external factor, such as the dark/light period, was necessary for synchronization of GPDH-2 transcription and activity.
Fil: Stroppa, Maria Mercedes. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Carriazo, Carlota. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Gerez, Nelia Martha. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
Fil: Garcia, Beatriz Alicia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones En Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas; Argentina
description Triatoma infestans, the main vector of Chagas disease, is a blood-sucking insect. Flight dispersal of adults is the most important mechanism for reinfestation of houses after insecticide spraying. Flight muscles have two glycerol-3-phosphate dehydrogenase (GPDH) isoforms: GPDH-1 is involved in flight metabolism and GPDH-2 provides lipid precursors. In this study, we explored the profile of GPDH expression in females and males adult flight muscles under light/dark cycle, constant light, and constant dark conditions. Under constant dark conditions, GPDH-1 flight muscles of T. infestans showed a rhythmic pattern of transcription synchronous with a rhythmic profile of activity suggesting regulation by the endogenous circadian clock. Otherwise, the GPDH-2 expression analysis showed no regulation by the endogenous clock, but showed that an external factor, such as the dark/light period, was necessary for synchronization of GPDH-2 transcription and activity.
publishDate 2014
dc.date.none.fl_str_mv 2014-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/11403
Stroppa, Maria Mercedes; Carriazo, Carlota; Gerez, Nelia Martha; Garcia, Beatriz Alicia; Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles; American Society Of Tropical Medicine And Hygiene; American Journal Of Tropical Medicine And Hygiene; 91; 2; 7-2014; 399-405
0002-9637
url http://hdl.handle.net/11336/11403
identifier_str_mv Stroppa, Maria Mercedes; Carriazo, Carlota; Gerez, Nelia Martha; Garcia, Beatriz Alicia; Daily Variations in the Glycerol-3-Phosphate Dehydrogenase isoforms expression in Triatoma infestans flight muscles; American Society Of Tropical Medicine And Hygiene; American Journal Of Tropical Medicine And Hygiene; 91; 2; 7-2014; 399-405
0002-9637
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.4269/ajtmh.13-0556
info:eu-repo/semantics/altIdentifier/url/http://www.ajtmh.org/content/91/2/399
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125269/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Society Of Tropical Medicine And Hygiene
publisher.none.fl_str_mv American Society Of Tropical Medicine And Hygiene
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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