Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites

Autores
Fundia, Ariela Freya; Acevedo, Susana Haydee; Larripa, Irene Beatriz
Año de publicación
2000
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. 85(10):October 2000 leukemia, suggesting the presence of chromosome instability. Bands 9q34 or 22q11 were not damaged in these patients, demonstrating that the origin of the Philadelphia chromosome is independent of spontaneous breakage or fragile site expression.
Fil: Fundia, Ariela Freya. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Acevedo, Susana Haydee. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas ; Argentina
Fil: Larripa, Irene Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Materia
CHRONIC MYELOID LEUKEMIA
CHROMOSOME FRAGILE SITES
SPONTANEOUS CHROMOSOME ABERRATIONS
PHILADELPHIA REARRANGEMENT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/55098
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sitesFundia, Ariela FreyaAcevedo, Susana HaydeeLarripa, Irene BeatrizCHRONIC MYELOID LEUKEMIACHROMOSOME FRAGILE SITESSPONTANEOUS CHROMOSOME ABERRATIONSPHILADELPHIA REARRANGEMENThttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. 85(10):October 2000 leukemia, suggesting the presence of chromosome instability. Bands 9q34 or 22q11 were not damaged in these patients, demonstrating that the origin of the Philadelphia chromosome is independent of spontaneous breakage or fragile site expression.Fil: Fundia, Ariela Freya. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Acevedo, Susana Haydee. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas ; ArgentinaFil: Larripa, Irene Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFerrata Storti Foundation2000-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/55098Fundia, Ariela Freya; Acevedo, Susana Haydee; Larripa, Irene Beatriz; Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites; Ferrata Storti Foundation; Haematologica; 85; 10; 10-2000; 1104-11060390-60781592-8721CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.haematologica.org/content/85/10/1104.longinfo:eu-repo/semantics/altIdentifier/pmid/11025611info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:58:02Zoai:ri.conicet.gov.ar:11336/55098instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:58:03.214CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
title Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
spellingShingle Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
Fundia, Ariela Freya
CHRONIC MYELOID LEUKEMIA
CHROMOSOME FRAGILE SITES
SPONTANEOUS CHROMOSOME ABERRATIONS
PHILADELPHIA REARRANGEMENT
title_short Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
title_full Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
title_fullStr Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
title_full_unstemmed Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
title_sort Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites
dc.creator.none.fl_str_mv Fundia, Ariela Freya
Acevedo, Susana Haydee
Larripa, Irene Beatriz
author Fundia, Ariela Freya
author_facet Fundia, Ariela Freya
Acevedo, Susana Haydee
Larripa, Irene Beatriz
author_role author
author2 Acevedo, Susana Haydee
Larripa, Irene Beatriz
author2_role author
author
dc.subject.none.fl_str_mv CHRONIC MYELOID LEUKEMIA
CHROMOSOME FRAGILE SITES
SPONTANEOUS CHROMOSOME ABERRATIONS
PHILADELPHIA REARRANGEMENT
topic CHRONIC MYELOID LEUKEMIA
CHROMOSOME FRAGILE SITES
SPONTANEOUS CHROMOSOME ABERRATIONS
PHILADELPHIA REARRANGEMENT
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. 85(10):October 2000 leukemia, suggesting the presence of chromosome instability. Bands 9q34 or 22q11 were not damaged in these patients, demonstrating that the origin of the Philadelphia chromosome is independent of spontaneous breakage or fragile site expression.
Fil: Fundia, Ariela Freya. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Acevedo, Susana Haydee. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas ; Argentina
Fil: Larripa, Irene Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
description Increased frequencies of spontaneous and bromodeoxyuridine induced breakages with a non-random distribution of breakpoints were found in patients with chronic myeloid scientific correspondence 1105 Haematologica vol. 85(10):October 2000 leukemia, suggesting the presence of chromosome instability. Bands 9q34 or 22q11 were not damaged in these patients, demonstrating that the origin of the Philadelphia chromosome is independent of spontaneous breakage or fragile site expression.
publishDate 2000
dc.date.none.fl_str_mv 2000-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/55098
Fundia, Ariela Freya; Acevedo, Susana Haydee; Larripa, Irene Beatriz; Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites; Ferrata Storti Foundation; Haematologica; 85; 10; 10-2000; 1104-1106
0390-6078
1592-8721
CONICET Digital
CONICET
url http://hdl.handle.net/11336/55098
identifier_str_mv Fundia, Ariela Freya; Acevedo, Susana Haydee; Larripa, Irene Beatriz; Chromosomal instability in chronic myeloid leukemia: Philadelphia breakpoints are independent of spontaneous breakage and fragile sites; Ferrata Storti Foundation; Haematologica; 85; 10; 10-2000; 1104-1106
0390-6078
1592-8721
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.haematologica.org/content/85/10/1104.long
info:eu-repo/semantics/altIdentifier/pmid/11025611
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Ferrata Storti Foundation
publisher.none.fl_str_mv Ferrata Storti Foundation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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