Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples

Autores
Canales, Maria Romina; Marino Repizo, Leonardo; Reta, Mario Roberto; Cerutti, Soledad
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A multi-response optimization of a green and efficient solid phase extraction (SPE) sample treatment using non-modified multi-walled carbon nanotubes combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for the quantification of ten heterocyclic aromatic amines (HAAs) in river and reservoir surface water samples. The proposed methodology was evaluated with the employment of experimental designs, which provided to greening the approach. Ultra-trace amounts of HAAs were retained into the SPE cartridge. Then, these analytes were removed from the carbon nanotubes with 0.8 mL of a mixture of acetonitrile/water with 0.1 % of formic acid. Under the optimal conditions, linearity was achieved for concentration levels ranging from 0.20 µg L-1 to 500 µg L-1, with regression coefficients (R2) from 0.990 to 0.998. Limits of detection varying from 0.06 µg L-1 and 0.23 µg L-1 were attained, the relative standard deviations (n=3) varied from 1.7 to 6.4, and extraction recoveries ranged from 90.6 % to 106.0 % for all the analytes. Results of the presence of HAAs found in the river samples demonstrated levels from 0.16 µg L-1 to 0.53 µg L-1; meanwhile, in the reservoir, the levels were higher, from 0.37 µg L-1 to 0.93 µg L-1. Finally, a comparative discussion was applied in order to assess the greenness of approaches for the determination of heterocyclic aromatic amines in surface water using the available metrics.
Fil: Canales, Maria Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Marino Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Reta, Mario Roberto. Universidad Nacional de La Plata; Argentina
Fil: Cerutti, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Materia
Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon nanotubes
Green certificate
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/104581
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/104581
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samplesCanales, Maria RominaMarino Repizo, LeonardoReta, Mario RobertoCerutti, SoledadHeterocyclic aromatic aminesSolid-phase extractionMulti-walled carbon nanotubesGreen certificatehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A multi-response optimization of a green and efficient solid phase extraction (SPE) sample treatment using non-modified multi-walled carbon nanotubes combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for the quantification of ten heterocyclic aromatic amines (HAAs) in river and reservoir surface water samples. The proposed methodology was evaluated with the employment of experimental designs, which provided to greening the approach. Ultra-trace amounts of HAAs were retained into the SPE cartridge. Then, these analytes were removed from the carbon nanotubes with 0.8 mL of a mixture of acetonitrile/water with 0.1 % of formic acid. Under the optimal conditions, linearity was achieved for concentration levels ranging from 0.20 µg L-1 to 500 µg L-1, with regression coefficients (R2) from 0.990 to 0.998. Limits of detection varying from 0.06 µg L-1 and 0.23 µg L-1 were attained, the relative standard deviations (n=3) varied from 1.7 to 6.4, and extraction recoveries ranged from 90.6 % to 106.0 % for all the analytes. Results of the presence of HAAs found in the river samples demonstrated levels from 0.16 µg L-1 to 0.53 µg L-1; meanwhile, in the reservoir, the levels were higher, from 0.37 µg L-1 to 0.93 µg L-1. Finally, a comparative discussion was applied in order to assess the greenness of approaches for the determination of heterocyclic aromatic amines in surface water using the available metrics.Fil: Canales, Maria Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Marino Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Reta, Mario Roberto. Universidad Nacional de La Plata; ArgentinaFil: Cerutti, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaRoyal Society of Chemistry2020-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/104581Canales, Maria Romina; Marino Repizo, Leonardo; Reta, Mario Roberto; Cerutti, Soledad; Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples; Royal Society of Chemistry; Analytical Methods; 2-20201759-9660CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2020/AY/C9AY02712Binfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:47:00Zoai:ri.conicet.gov.ar:11336/104581instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:47:00.744CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
spellingShingle Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
Canales, Maria Romina
Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon nanotubes
Green certificate
title_short Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_full Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_fullStr Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_full_unstemmed Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_sort Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
dc.creator.none.fl_str_mv Canales, Maria Romina
Marino Repizo, Leonardo
Reta, Mario Roberto
Cerutti, Soledad
author Canales, Maria Romina
author_facet Canales, Maria Romina
Marino Repizo, Leonardo
Reta, Mario Roberto
Cerutti, Soledad
author_role author
author2 Marino Repizo, Leonardo
Reta, Mario Roberto
Cerutti, Soledad
author2_role author
author
author
dc.subject.none.fl_str_mv Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon nanotubes
Green certificate
topic Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon nanotubes
Green certificate
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A multi-response optimization of a green and efficient solid phase extraction (SPE) sample treatment using non-modified multi-walled carbon nanotubes combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for the quantification of ten heterocyclic aromatic amines (HAAs) in river and reservoir surface water samples. The proposed methodology was evaluated with the employment of experimental designs, which provided to greening the approach. Ultra-trace amounts of HAAs were retained into the SPE cartridge. Then, these analytes were removed from the carbon nanotubes with 0.8 mL of a mixture of acetonitrile/water with 0.1 % of formic acid. Under the optimal conditions, linearity was achieved for concentration levels ranging from 0.20 µg L-1 to 500 µg L-1, with regression coefficients (R2) from 0.990 to 0.998. Limits of detection varying from 0.06 µg L-1 and 0.23 µg L-1 were attained, the relative standard deviations (n=3) varied from 1.7 to 6.4, and extraction recoveries ranged from 90.6 % to 106.0 % for all the analytes. Results of the presence of HAAs found in the river samples demonstrated levels from 0.16 µg L-1 to 0.53 µg L-1; meanwhile, in the reservoir, the levels were higher, from 0.37 µg L-1 to 0.93 µg L-1. Finally, a comparative discussion was applied in order to assess the greenness of approaches for the determination of heterocyclic aromatic amines in surface water using the available metrics.
Fil: Canales, Maria Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Marino Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Reta, Mario Roberto. Universidad Nacional de La Plata; Argentina
Fil: Cerutti, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
description A multi-response optimization of a green and efficient solid phase extraction (SPE) sample treatment using non-modified multi-walled carbon nanotubes combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for the quantification of ten heterocyclic aromatic amines (HAAs) in river and reservoir surface water samples. The proposed methodology was evaluated with the employment of experimental designs, which provided to greening the approach. Ultra-trace amounts of HAAs were retained into the SPE cartridge. Then, these analytes were removed from the carbon nanotubes with 0.8 mL of a mixture of acetonitrile/water with 0.1 % of formic acid. Under the optimal conditions, linearity was achieved for concentration levels ranging from 0.20 µg L-1 to 500 µg L-1, with regression coefficients (R2) from 0.990 to 0.998. Limits of detection varying from 0.06 µg L-1 and 0.23 µg L-1 were attained, the relative standard deviations (n=3) varied from 1.7 to 6.4, and extraction recoveries ranged from 90.6 % to 106.0 % for all the analytes. Results of the presence of HAAs found in the river samples demonstrated levels from 0.16 µg L-1 to 0.53 µg L-1; meanwhile, in the reservoir, the levels were higher, from 0.37 µg L-1 to 0.93 µg L-1. Finally, a comparative discussion was applied in order to assess the greenness of approaches for the determination of heterocyclic aromatic amines in surface water using the available metrics.
publishDate 2020
dc.date.none.fl_str_mv 2020-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/104581
Canales, Maria Romina; Marino Repizo, Leonardo; Reta, Mario Roberto; Cerutti, Soledad; Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples; Royal Society of Chemistry; Analytical Methods; 2-2020
1759-9660
CONICET Digital
CONICET
url http://hdl.handle.net/11336/104581
identifier_str_mv Canales, Maria Romina; Marino Repizo, Leonardo; Reta, Mario Roberto; Cerutti, Soledad; Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples; Royal Society of Chemistry; Analytical Methods; 2-2020
1759-9660
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2020/AY/C9AY02712B
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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