Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades

Autores
Delvitto, Ailin; Lavagnino, Nicolas Jose
Año de publicación
2023
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Omic Sciences are presented as having the potential to carry out complex approaches to the phenomena they study, as well as the capacity to intervene on human health through the development of technologies for diagnosis and treatment of disease. In this regard, we show an epistemological analysis of the use and scope of complex conceptualizations of gene action in the genotype-phenotype relationship in Omic Sciences. In particular, we focus on whether or not epistemological simplifications occur when human diseases are studied Our comparative analysis shows that, in general, in Omic Sciences there are both simple and complex conceptualizations of gene action in the genotype-phenotype relationship, while in omics investigations that address human diseases an exacerbation of simplifying conceptualizations is found. It is discussed whether this epistemological simplification is favored in scenarios of intervention in human health, such as the generation of knowledge for the development of Omics technologies for improved diagnosis and treatment of disease. Overall, as in other fields of Natural Sciences, in omics studies of disease a necessary link between epistemological simplifications and the promise of intervention is found.
Fil: Delvitto, Ailin. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Lavagnino, Nicolas Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina
Materia
BIOLOGICAL BASIS OF DISEASE
EPISTEMOLOGICAL SIMPLIFICATION
GENOMICS
OMIC SCIENCES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/221115
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedadesLimitations of complexity in omic science: epistemological simplification in the approach to diseaseDelvitto, AilinLavagnino, Nicolas JoseBIOLOGICAL BASIS OF DISEASEEPISTEMOLOGICAL SIMPLIFICATIONGENOMICSOMIC SCIENCEShttps://purl.org/becyt/ford/6.3https://purl.org/becyt/ford/6Omic Sciences are presented as having the potential to carry out complex approaches to the phenomena they study, as well as the capacity to intervene on human health through the development of technologies for diagnosis and treatment of disease. In this regard, we show an epistemological analysis of the use and scope of complex conceptualizations of gene action in the genotype-phenotype relationship in Omic Sciences. In particular, we focus on whether or not epistemological simplifications occur when human diseases are studied Our comparative analysis shows that, in general, in Omic Sciences there are both simple and complex conceptualizations of gene action in the genotype-phenotype relationship, while in omics investigations that address human diseases an exacerbation of simplifying conceptualizations is found. It is discussed whether this epistemological simplification is favored in scenarios of intervention in human health, such as the generation of knowledge for the development of Omics technologies for improved diagnosis and treatment of disease. Overall, as in other fields of Natural Sciences, in omics studies of disease a necessary link between epistemological simplifications and the promise of intervention is found.Fil: Delvitto, Ailin. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Lavagnino, Nicolas Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; ArgentinaUniversidade Federal de Santa Catarina2023-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/221115Delvitto, Ailin; Lavagnino, Nicolas Jose; Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades; Universidade Federal de Santa Catarina; Principia; 27; 2; 10-2023; 165-1941414-42471808-1711CONICET DigitalCONICETspainfo:eu-repo/semantics/altIdentifier/url/https://periodicos.ufsc.br/index.php/principia/article/view/85523info:eu-repo/semantics/altIdentifier/doi/10.5007/1808-1711.2023.e85523info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:47:14Zoai:ri.conicet.gov.ar:11336/221115instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:47:14.498CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
Limitations of complexity in omic science: epistemological simplification in the approach to disease
title Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
spellingShingle Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
Delvitto, Ailin
BIOLOGICAL BASIS OF DISEASE
EPISTEMOLOGICAL SIMPLIFICATION
GENOMICS
OMIC SCIENCES
title_short Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
title_full Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
title_fullStr Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
title_full_unstemmed Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
title_sort Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades
dc.creator.none.fl_str_mv Delvitto, Ailin
Lavagnino, Nicolas Jose
author Delvitto, Ailin
author_facet Delvitto, Ailin
Lavagnino, Nicolas Jose
author_role author
author2 Lavagnino, Nicolas Jose
author2_role author
dc.subject.none.fl_str_mv BIOLOGICAL BASIS OF DISEASE
EPISTEMOLOGICAL SIMPLIFICATION
GENOMICS
OMIC SCIENCES
topic BIOLOGICAL BASIS OF DISEASE
EPISTEMOLOGICAL SIMPLIFICATION
GENOMICS
OMIC SCIENCES
purl_subject.fl_str_mv https://purl.org/becyt/ford/6.3
https://purl.org/becyt/ford/6
dc.description.none.fl_txt_mv Omic Sciences are presented as having the potential to carry out complex approaches to the phenomena they study, as well as the capacity to intervene on human health through the development of technologies for diagnosis and treatment of disease. In this regard, we show an epistemological analysis of the use and scope of complex conceptualizations of gene action in the genotype-phenotype relationship in Omic Sciences. In particular, we focus on whether or not epistemological simplifications occur when human diseases are studied Our comparative analysis shows that, in general, in Omic Sciences there are both simple and complex conceptualizations of gene action in the genotype-phenotype relationship, while in omics investigations that address human diseases an exacerbation of simplifying conceptualizations is found. It is discussed whether this epistemological simplification is favored in scenarios of intervention in human health, such as the generation of knowledge for the development of Omics technologies for improved diagnosis and treatment of disease. Overall, as in other fields of Natural Sciences, in omics studies of disease a necessary link between epistemological simplifications and the promise of intervention is found.
Fil: Delvitto, Ailin. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Lavagnino, Nicolas Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Instituto de Filosofía "Dr. Alejandro Korn"; Argentina
description Omic Sciences are presented as having the potential to carry out complex approaches to the phenomena they study, as well as the capacity to intervene on human health through the development of technologies for diagnosis and treatment of disease. In this regard, we show an epistemological analysis of the use and scope of complex conceptualizations of gene action in the genotype-phenotype relationship in Omic Sciences. In particular, we focus on whether or not epistemological simplifications occur when human diseases are studied Our comparative analysis shows that, in general, in Omic Sciences there are both simple and complex conceptualizations of gene action in the genotype-phenotype relationship, while in omics investigations that address human diseases an exacerbation of simplifying conceptualizations is found. It is discussed whether this epistemological simplification is favored in scenarios of intervention in human health, such as the generation of knowledge for the development of Omics technologies for improved diagnosis and treatment of disease. Overall, as in other fields of Natural Sciences, in omics studies of disease a necessary link between epistemological simplifications and the promise of intervention is found.
publishDate 2023
dc.date.none.fl_str_mv 2023-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/221115
Delvitto, Ailin; Lavagnino, Nicolas Jose; Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades; Universidade Federal de Santa Catarina; Principia; 27; 2; 10-2023; 165-194
1414-4247
1808-1711
CONICET Digital
CONICET
url http://hdl.handle.net/11336/221115
identifier_str_mv Delvitto, Ailin; Lavagnino, Nicolas Jose; Limitaciones de la complejidad en las ciencias ómicas: simplificación epistemológica en el abordaje de enfermedades; Universidade Federal de Santa Catarina; Principia; 27; 2; 10-2023; 165-194
1414-4247
1808-1711
CONICET Digital
CONICET
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://periodicos.ufsc.br/index.php/principia/article/view/85523
info:eu-repo/semantics/altIdentifier/doi/10.5007/1808-1711.2023.e85523
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Catarina
publisher.none.fl_str_mv Universidade Federal de Santa Catarina
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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