Glial modulation by N-acylethanolamides in brain injury and neurodegeneration

Autores
Herrera, María Inés; Kolliker Frers, Rodolfo Alberto; Barreto, George; Blanco, Eduardo; Capani, Francisco
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.
Fil: Herrera, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Kolliker Frers, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Barreto, George. Pontificia Universidad Javeriana; Colombia
Fil: Blanco, Eduardo. Universidad de Lleida; España
Fil: Capani, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Universidad Argentina "John F. Kennedy"; Argentina
Materia
GLIOSIS
N-ACYLETHANOLAMIDES
NEUROINFLAMMATION
NEUROPROTECTION
PPARΑ
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/113893
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Glial modulation by N-acylethanolamides in brain injury and neurodegenerationHerrera, María InésKolliker Frers, Rodolfo AlbertoBarreto, GeorgeBlanco, EduardoCapani, FranciscoGLIOSISN-ACYLETHANOLAMIDESNEUROINFLAMMATIONNEUROPROTECTIONPPARΑhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.Fil: Herrera, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Kolliker Frers, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Barreto, George. Pontificia Universidad Javeriana; ColombiaFil: Blanco, Eduardo. Universidad de Lleida; EspañaFil: Capani, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Universidad Argentina "John F. Kennedy"; ArgentinaFrontiers Media S.A.2016-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/113893Herrera, María Inés; Kolliker Frers, Rodolfo Alberto; Barreto, George; Blanco, Eduardo; Capani, Francisco; Glial modulation by N-acylethanolamides in brain injury and neurodegeneration; Frontiers Media S.A.; Frontiers in Aging Neuroscience; 4-2016; 25-351663-4365CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3389/fnagi.2016.00081info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnagi.2016.00081/fullinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:39:30Zoai:ri.conicet.gov.ar:11336/113893instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:39:31.106CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
title Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
spellingShingle Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
Herrera, María Inés
GLIOSIS
N-ACYLETHANOLAMIDES
NEUROINFLAMMATION
NEUROPROTECTION
PPARΑ
title_short Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
title_full Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
title_fullStr Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
title_full_unstemmed Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
title_sort Glial modulation by N-acylethanolamides in brain injury and neurodegeneration
dc.creator.none.fl_str_mv Herrera, María Inés
Kolliker Frers, Rodolfo Alberto
Barreto, George
Blanco, Eduardo
Capani, Francisco
author Herrera, María Inés
author_facet Herrera, María Inés
Kolliker Frers, Rodolfo Alberto
Barreto, George
Blanco, Eduardo
Capani, Francisco
author_role author
author2 Kolliker Frers, Rodolfo Alberto
Barreto, George
Blanco, Eduardo
Capani, Francisco
author2_role author
author
author
author
dc.subject.none.fl_str_mv GLIOSIS
N-ACYLETHANOLAMIDES
NEUROINFLAMMATION
NEUROPROTECTION
PPARΑ
topic GLIOSIS
N-ACYLETHANOLAMIDES
NEUROINFLAMMATION
NEUROPROTECTION
PPARΑ
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.
Fil: Herrera, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Kolliker Frers, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Barreto, George. Pontificia Universidad Javeriana; Colombia
Fil: Blanco, Eduardo. Universidad de Lleida; España
Fil: Capani, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Universidad Argentina "John F. Kennedy"; Argentina
description Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.
publishDate 2016
dc.date.none.fl_str_mv 2016-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/113893
Herrera, María Inés; Kolliker Frers, Rodolfo Alberto; Barreto, George; Blanco, Eduardo; Capani, Francisco; Glial modulation by N-acylethanolamides in brain injury and neurodegeneration; Frontiers Media S.A.; Frontiers in Aging Neuroscience; 4-2016; 25-35
1663-4365
CONICET Digital
CONICET
url http://hdl.handle.net/11336/113893
identifier_str_mv Herrera, María Inés; Kolliker Frers, Rodolfo Alberto; Barreto, George; Blanco, Eduardo; Capani, Francisco; Glial modulation by N-acylethanolamides in brain injury and neurodegeneration; Frontiers Media S.A.; Frontiers in Aging Neuroscience; 4-2016; 25-35
1663-4365
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3389/fnagi.2016.00081
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnagi.2016.00081/full
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media S.A.
publisher.none.fl_str_mv Frontiers Media S.A.
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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