Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups

Autores
Caputo, Mariela; Corach, Daniel
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objective: Genetic data have complemented archaeological and linguistic investigations for understanding the peopling of the Americas. Aiming to investigate the Native South American genetic background in Argentina, seven Amerindian and one urban population were selected. The analysis focused on locus D9S1120 due to its potential anthropological information about Native American origins. Methods: The sample set included 603 individuals belonging to nine isolated Argentinean aboriginal communities from seven tribes (N=296), 100 individuals living in Buenos Aires city, and three potentially parental population references samples (N=207). We computed allele and genotype frequency distributions, genetic distances, and pairwise differences among and within them. Admixture proportion was determined by means of typing 13 autosomal short tandem repeats plus D9S1120 in all populations, and comparing the data with those from three parental groups including Native American, European and Sub Saharan West African. Results: The Native American-specific allele 9RA was found at an average frequency of 0.26 in aboriginal groups. Statistically significant differences were observed among the Native American groups when compared with the Buenos Aires urban population using analysis of molecular variance (AMOVA) (Fst=0.05669; P<0.0001). Admixture analysis denoted different results between the cohorts of Amerindian samples displaying the specific 9RA allele, compared with those lacking it. A linear correlation was established between positive 9RA and Native American ancestry. Conclusions: Autosomal-based genetic admixture showed that the studied communities have considerable European and Native America contributions. Our results concerning D9S1120 further contribute to a better understanding of the admixture process between Sub Saharan African, Native American, and European individuals that shaped the genetic background of Argentinean extant population.
Fil: Caputo, Mariela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Locus
Genetic
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/38748
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/38748
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network_name_str CONICET Digital (CONICET)
spelling Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groupsCaputo, MarielaCorach, DanielLocusGenetichttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Objective: Genetic data have complemented archaeological and linguistic investigations for understanding the peopling of the Americas. Aiming to investigate the Native South American genetic background in Argentina, seven Amerindian and one urban population were selected. The analysis focused on locus D9S1120 due to its potential anthropological information about Native American origins. Methods: The sample set included 603 individuals belonging to nine isolated Argentinean aboriginal communities from seven tribes (N=296), 100 individuals living in Buenos Aires city, and three potentially parental population references samples (N=207). We computed allele and genotype frequency distributions, genetic distances, and pairwise differences among and within them. Admixture proportion was determined by means of typing 13 autosomal short tandem repeats plus D9S1120 in all populations, and comparing the data with those from three parental groups including Native American, European and Sub Saharan West African. Results: The Native American-specific allele 9RA was found at an average frequency of 0.26 in aboriginal groups. Statistically significant differences were observed among the Native American groups when compared with the Buenos Aires urban population using analysis of molecular variance (AMOVA) (Fst=0.05669; P<0.0001). Admixture analysis denoted different results between the cohorts of Amerindian samples displaying the specific 9RA allele, compared with those lacking it. A linear correlation was established between positive 9RA and Native American ancestry. Conclusions: Autosomal-based genetic admixture showed that the studied communities have considerable European and Native America contributions. Our results concerning D9S1120 further contribute to a better understanding of the admixture process between Sub Saharan African, Native American, and European individuals that shaped the genetic background of Argentinean extant population.Fil: Caputo, Mariela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaWiley-liss, Div John Wiley & Sons Inc2016-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/38748Caputo, Mariela; Corach, Daniel; Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups; Wiley-liss, Div John Wiley & Sons Inc; American Journal of Human Biology; 28; 1; 1-2016; 57-661042-0533CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1002/ajhb.22755info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ajhb.22755/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:46:27Zoai:ri.conicet.gov.ar:11336/38748instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:46:27.763CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
title Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
spellingShingle Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
Caputo, Mariela
Locus
Genetic
title_short Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
title_full Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
title_fullStr Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
title_full_unstemmed Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
title_sort Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups
dc.creator.none.fl_str_mv Caputo, Mariela
Corach, Daniel
author Caputo, Mariela
author_facet Caputo, Mariela
Corach, Daniel
author_role author
author2 Corach, Daniel
author2_role author
dc.subject.none.fl_str_mv Locus
Genetic
topic Locus
Genetic
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Objective: Genetic data have complemented archaeological and linguistic investigations for understanding the peopling of the Americas. Aiming to investigate the Native South American genetic background in Argentina, seven Amerindian and one urban population were selected. The analysis focused on locus D9S1120 due to its potential anthropological information about Native American origins. Methods: The sample set included 603 individuals belonging to nine isolated Argentinean aboriginal communities from seven tribes (N=296), 100 individuals living in Buenos Aires city, and three potentially parental population references samples (N=207). We computed allele and genotype frequency distributions, genetic distances, and pairwise differences among and within them. Admixture proportion was determined by means of typing 13 autosomal short tandem repeats plus D9S1120 in all populations, and comparing the data with those from three parental groups including Native American, European and Sub Saharan West African. Results: The Native American-specific allele 9RA was found at an average frequency of 0.26 in aboriginal groups. Statistically significant differences were observed among the Native American groups when compared with the Buenos Aires urban population using analysis of molecular variance (AMOVA) (Fst=0.05669; P<0.0001). Admixture analysis denoted different results between the cohorts of Amerindian samples displaying the specific 9RA allele, compared with those lacking it. A linear correlation was established between positive 9RA and Native American ancestry. Conclusions: Autosomal-based genetic admixture showed that the studied communities have considerable European and Native America contributions. Our results concerning D9S1120 further contribute to a better understanding of the admixture process between Sub Saharan African, Native American, and European individuals that shaped the genetic background of Argentinean extant population.
Fil: Caputo, Mariela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Corach, Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Servicio de Huellas Digitales Genéticas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Objective: Genetic data have complemented archaeological and linguistic investigations for understanding the peopling of the Americas. Aiming to investigate the Native South American genetic background in Argentina, seven Amerindian and one urban population were selected. The analysis focused on locus D9S1120 due to its potential anthropological information about Native American origins. Methods: The sample set included 603 individuals belonging to nine isolated Argentinean aboriginal communities from seven tribes (N=296), 100 individuals living in Buenos Aires city, and three potentially parental population references samples (N=207). We computed allele and genotype frequency distributions, genetic distances, and pairwise differences among and within them. Admixture proportion was determined by means of typing 13 autosomal short tandem repeats plus D9S1120 in all populations, and comparing the data with those from three parental groups including Native American, European and Sub Saharan West African. Results: The Native American-specific allele 9RA was found at an average frequency of 0.26 in aboriginal groups. Statistically significant differences were observed among the Native American groups when compared with the Buenos Aires urban population using analysis of molecular variance (AMOVA) (Fst=0.05669; P<0.0001). Admixture analysis denoted different results between the cohorts of Amerindian samples displaying the specific 9RA allele, compared with those lacking it. A linear correlation was established between positive 9RA and Native American ancestry. Conclusions: Autosomal-based genetic admixture showed that the studied communities have considerable European and Native America contributions. Our results concerning D9S1120 further contribute to a better understanding of the admixture process between Sub Saharan African, Native American, and European individuals that shaped the genetic background of Argentinean extant population.
publishDate 2016
dc.date.none.fl_str_mv 2016-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/38748
Caputo, Mariela; Corach, Daniel; Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups; Wiley-liss, Div John Wiley & Sons Inc; American Journal of Human Biology; 28; 1; 1-2016; 57-66
1042-0533
CONICET Digital
CONICET
url http://hdl.handle.net/11336/38748
identifier_str_mv Caputo, Mariela; Corach, Daniel; Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups; Wiley-liss, Div John Wiley & Sons Inc; American Journal of Human Biology; 28; 1; 1-2016; 57-66
1042-0533
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1002/ajhb.22755
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/ajhb.22755/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley-liss, Div John Wiley & Sons Inc
publisher.none.fl_str_mv Wiley-liss, Div John Wiley & Sons Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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