Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis

Autores
Romero, Marta D.; Muiño, Juan Carlos; Bianco, German Ariel; Ferrero, Mercedes; Juarez, Claudio P.; Luna, José Domingo; Rabinovich, Gabriel Adrián
Año de publicación
2006
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Galectin (Gal)-1, an endogenous lectin found at sites of immune privilege, plays a critical role in the regulation of the immune response. Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models of autoimmunity. The purpose of this work was to investigate the occurrence of circulating anti-Gal-1 antibodies in patients with autoimmune and infectious uveitis as potential determinant factors of disease progression.
Fil: Romero, Marta D.. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Fundación Ver; Argentina. Laboratorio Inmunopatología Investigación y Docencia LIIDO; Argentina
Fil: Muiño, Juan Carlos. Universidad Nacional de Córdoba; Argentina. Fundación Ver; Argentina
Fil: Bianco, German Ariel. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Ferrero, Mercedes. Laboratorio Inmunopatología Investigación y Docencia LIIDO; Argentina. Fundación Ver; Argentina
Fil: Juarez, Claudio P.. Fundación Ver; Argentina
Fil: Luna, José Domingo. Fundación Ver; Argentina
Fil: Rabinovich, Gabriel Adrián. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Materia
Autoimmune Diseases
Enzyme-Linked Immunosorbent Assay
Eye Infections
Galectin 1
Uveitis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/28532
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitisRomero, Marta D.Muiño, Juan CarlosBianco, German ArielFerrero, MercedesJuarez, Claudio P.Luna, José DomingoRabinovich, Gabriel AdriánAutoimmune DiseasesEnzyme-Linked Immunosorbent AssayEye InfectionsGalectin 1Uveitishttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Galectin (Gal)-1, an endogenous lectin found at sites of immune privilege, plays a critical role in the regulation of the immune response. Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models of autoimmunity. The purpose of this work was to investigate the occurrence of circulating anti-Gal-1 antibodies in patients with autoimmune and infectious uveitis as potential determinant factors of disease progression.Fil: Romero, Marta D.. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Fundación Ver; Argentina. Laboratorio Inmunopatología Investigación y Docencia LIIDO; ArgentinaFil: Muiño, Juan Carlos. Universidad Nacional de Córdoba; Argentina. Fundación Ver; ArgentinaFil: Bianco, German Ariel. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Ferrero, Mercedes. Laboratorio Inmunopatología Investigación y Docencia LIIDO; Argentina. Fundación Ver; ArgentinaFil: Juarez, Claudio P.. Fundación Ver; ArgentinaFil: Luna, José Domingo. Fundación Ver; ArgentinaFil: Rabinovich, Gabriel Adrián. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaAssociation for Research in Vision and Ophthalmology2006-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/28532Romero, Marta D.; Muiño, Juan Carlos; Bianco, German Ariel; Ferrero, Mercedes; Juarez, Claudio P.; et al.; Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis; Association for Research in Vision and Ophthalmology; Investigative Ophthalmology & Visual Science; 47; 4; 4-2006; 1550-15560146-04041552-5783CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://iovs.arvojournals.org/article.aspx?articleid=2202988info:eu-repo/semantics/altIdentifier/doi/10.1167/iovs.05-1234info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:01:29Zoai:ri.conicet.gov.ar:11336/28532instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:01:30.181CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
title Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
spellingShingle Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
Romero, Marta D.
Autoimmune Diseases
Enzyme-Linked Immunosorbent Assay
Eye Infections
Galectin 1
Uveitis
title_short Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
title_full Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
title_fullStr Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
title_full_unstemmed Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
title_sort Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
dc.creator.none.fl_str_mv Romero, Marta D.
Muiño, Juan Carlos
Bianco, German Ariel
Ferrero, Mercedes
Juarez, Claudio P.
Luna, José Domingo
Rabinovich, Gabriel Adrián
author Romero, Marta D.
author_facet Romero, Marta D.
Muiño, Juan Carlos
Bianco, German Ariel
Ferrero, Mercedes
Juarez, Claudio P.
Luna, José Domingo
Rabinovich, Gabriel Adrián
author_role author
author2 Muiño, Juan Carlos
Bianco, German Ariel
Ferrero, Mercedes
Juarez, Claudio P.
Luna, José Domingo
Rabinovich, Gabriel Adrián
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Autoimmune Diseases
Enzyme-Linked Immunosorbent Assay
Eye Infections
Galectin 1
Uveitis
topic Autoimmune Diseases
Enzyme-Linked Immunosorbent Assay
Eye Infections
Galectin 1
Uveitis
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Galectin (Gal)-1, an endogenous lectin found at sites of immune privilege, plays a critical role in the regulation of the immune response. Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models of autoimmunity. The purpose of this work was to investigate the occurrence of circulating anti-Gal-1 antibodies in patients with autoimmune and infectious uveitis as potential determinant factors of disease progression.
Fil: Romero, Marta D.. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Fundación Ver; Argentina. Laboratorio Inmunopatología Investigación y Docencia LIIDO; Argentina
Fil: Muiño, Juan Carlos. Universidad Nacional de Córdoba; Argentina. Fundación Ver; Argentina
Fil: Bianco, German Ariel. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: Ferrero, Mercedes. Laboratorio Inmunopatología Investigación y Docencia LIIDO; Argentina. Fundación Ver; Argentina
Fil: Juarez, Claudio P.. Fundación Ver; Argentina
Fil: Luna, José Domingo. Fundación Ver; Argentina
Fil: Rabinovich, Gabriel Adrián. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
description Galectin (Gal)-1, an endogenous lectin found at sites of immune privilege, plays a critical role in the regulation of the immune response. Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models of autoimmunity. The purpose of this work was to investigate the occurrence of circulating anti-Gal-1 antibodies in patients with autoimmune and infectious uveitis as potential determinant factors of disease progression.
publishDate 2006
dc.date.none.fl_str_mv 2006-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/28532
Romero, Marta D.; Muiño, Juan Carlos; Bianco, German Ariel; Ferrero, Mercedes; Juarez, Claudio P.; et al.; Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis; Association for Research in Vision and Ophthalmology; Investigative Ophthalmology & Visual Science; 47; 4; 4-2006; 1550-1556
0146-0404
1552-5783
CONICET Digital
CONICET
url http://hdl.handle.net/11336/28532
identifier_str_mv Romero, Marta D.; Muiño, Juan Carlos; Bianco, German Ariel; Ferrero, Mercedes; Juarez, Claudio P.; et al.; Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis; Association for Research in Vision and Ophthalmology; Investigative Ophthalmology & Visual Science; 47; 4; 4-2006; 1550-1556
0146-0404
1552-5783
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://iovs.arvojournals.org/article.aspx?articleid=2202988
info:eu-repo/semantics/altIdentifier/doi/10.1167/iovs.05-1234
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Association for Research in Vision and Ophthalmology
publisher.none.fl_str_mv Association for Research in Vision and Ophthalmology
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781200544301056
score 12.982451

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