Autophagy as an innate immunity response against pathogens: a Tango dance

Autores
Aguilera, Milton Osmar; Delgui, Laura Ruth; Reggiori, Fulvio; Romano, Patricia Silvia; Colombo, Maria Isabel
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Intracellular infections as well as changes in the cell nutritional environmentare main events that trigger cellular stress responses. One crucial cellresponse to stress conditions is autophagy. During the last 30 years, severalscenarios involving autophagy induction or inhibition over the course of anintracellular invasion by pathogens have been uncovered. In this review, wewill present how this knowledge was gained by studying different microorganisms.We intend to discuss how the cell, via autophagy, tries to repel theseattacks with the objective of destroying the intruder, but also how some pathogenshave developed strategies to subvert this. These two fates can be comparedwith a Tango, a dance originated in Buenos Aires, Argentina, in whichthe partner dancers are in close connection. One of them is the leader,embracing and involving the partner, but the follower may respond escapingfrom the leader. This joint dance is indeed highly synchronized and controlled,perfectly reflecting the interaction between autophagy and microorganism.
Fil: Aguilera, Milton Osmar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Delgui, Laura Ruth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Reggiori, Fulvio. University Aarhus; Dinamarca
Fil: Romano, Patricia Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Materia
AUTOPHAGY
PATHOGENS
INNATE IMMUNITY
VIRUS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/230506
Acceder
id CONICETDig_e74c201e5204420356b189dd1c9a77d6
oai_identifier_str oai:ri.conicet.gov.ar:11336/230506
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Autophagy as an innate immunity response against pathogens: a Tango danceAguilera, Milton OsmarDelgui, Laura RuthReggiori, FulvioRomano, Patricia SilviaColombo, Maria IsabelAUTOPHAGYPATHOGENSINNATE IMMUNITYVIRUShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Intracellular infections as well as changes in the cell nutritional environmentare main events that trigger cellular stress responses. One crucial cellresponse to stress conditions is autophagy. During the last 30 years, severalscenarios involving autophagy induction or inhibition over the course of anintracellular invasion by pathogens have been uncovered. In this review, wewill present how this knowledge was gained by studying different microorganisms.We intend to discuss how the cell, via autophagy, tries to repel theseattacks with the objective of destroying the intruder, but also how some pathogenshave developed strategies to subvert this. These two fates can be comparedwith a Tango, a dance originated in Buenos Aires, Argentina, in whichthe partner dancers are in close connection. One of them is the leader,embracing and involving the partner, but the follower may respond escapingfrom the leader. This joint dance is indeed highly synchronized and controlled,perfectly reflecting the interaction between autophagy and microorganism.Fil: Aguilera, Milton Osmar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Delgui, Laura Ruth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Reggiori, Fulvio. University Aarhus; DinamarcaFil: Romano, Patricia Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; ArgentinaJohn Wiley and Sons Inc2023-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/230506Aguilera, Milton Osmar; Delgui, Laura Ruth; Reggiori, Fulvio; Romano, Patricia Silvia; Colombo, Maria Isabel; Autophagy as an innate immunity response against pathogens: a Tango dance; John Wiley and Sons Inc; FEBS Letters; 598; 1; 12-2023; 140-1661873-3468CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14788info:eu-repo/semantics/altIdentifier/doi/10.1002/1873-3468.14788info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:57:03Zoai:ri.conicet.gov.ar:11336/230506instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:57:03.902CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Autophagy as an innate immunity response against pathogens: a Tango dance
title Autophagy as an innate immunity response against pathogens: a Tango dance
spellingShingle Autophagy as an innate immunity response against pathogens: a Tango dance
Aguilera, Milton Osmar
AUTOPHAGY
PATHOGENS
INNATE IMMUNITY
VIRUS
title_short Autophagy as an innate immunity response against pathogens: a Tango dance
title_full Autophagy as an innate immunity response against pathogens: a Tango dance
title_fullStr Autophagy as an innate immunity response against pathogens: a Tango dance
title_full_unstemmed Autophagy as an innate immunity response against pathogens: a Tango dance
title_sort Autophagy as an innate immunity response against pathogens: a Tango dance
dc.creator.none.fl_str_mv Aguilera, Milton Osmar
Delgui, Laura Ruth
Reggiori, Fulvio
Romano, Patricia Silvia
Colombo, Maria Isabel
author Aguilera, Milton Osmar
author_facet Aguilera, Milton Osmar
Delgui, Laura Ruth
Reggiori, Fulvio
Romano, Patricia Silvia
Colombo, Maria Isabel
author_role author
author2 Delgui, Laura Ruth
Reggiori, Fulvio
Romano, Patricia Silvia
Colombo, Maria Isabel
author2_role author
author
author
author
dc.subject.none.fl_str_mv AUTOPHAGY
PATHOGENS
INNATE IMMUNITY
VIRUS
topic AUTOPHAGY
PATHOGENS
INNATE IMMUNITY
VIRUS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Intracellular infections as well as changes in the cell nutritional environmentare main events that trigger cellular stress responses. One crucial cellresponse to stress conditions is autophagy. During the last 30 years, severalscenarios involving autophagy induction or inhibition over the course of anintracellular invasion by pathogens have been uncovered. In this review, wewill present how this knowledge was gained by studying different microorganisms.We intend to discuss how the cell, via autophagy, tries to repel theseattacks with the objective of destroying the intruder, but also how some pathogenshave developed strategies to subvert this. These two fates can be comparedwith a Tango, a dance originated in Buenos Aires, Argentina, in whichthe partner dancers are in close connection. One of them is the leader,embracing and involving the partner, but the follower may respond escapingfrom the leader. This joint dance is indeed highly synchronized and controlled,perfectly reflecting the interaction between autophagy and microorganism.
Fil: Aguilera, Milton Osmar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Delgui, Laura Ruth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Reggiori, Fulvio. University Aarhus; Dinamarca
Fil: Romano, Patricia Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
description Intracellular infections as well as changes in the cell nutritional environmentare main events that trigger cellular stress responses. One crucial cellresponse to stress conditions is autophagy. During the last 30 years, severalscenarios involving autophagy induction or inhibition over the course of anintracellular invasion by pathogens have been uncovered. In this review, wewill present how this knowledge was gained by studying different microorganisms.We intend to discuss how the cell, via autophagy, tries to repel theseattacks with the objective of destroying the intruder, but also how some pathogenshave developed strategies to subvert this. These two fates can be comparedwith a Tango, a dance originated in Buenos Aires, Argentina, in whichthe partner dancers are in close connection. One of them is the leader,embracing and involving the partner, but the follower may respond escapingfrom the leader. This joint dance is indeed highly synchronized and controlled,perfectly reflecting the interaction between autophagy and microorganism.
publishDate 2023
dc.date.none.fl_str_mv 2023-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/230506
Aguilera, Milton Osmar; Delgui, Laura Ruth; Reggiori, Fulvio; Romano, Patricia Silvia; Colombo, Maria Isabel; Autophagy as an innate immunity response against pathogens: a Tango dance; John Wiley and Sons Inc; FEBS Letters; 598; 1; 12-2023; 140-166
1873-3468
CONICET Digital
CONICET
url http://hdl.handle.net/11336/230506
identifier_str_mv Aguilera, Milton Osmar; Delgui, Laura Ruth; Reggiori, Fulvio; Romano, Patricia Silvia; Colombo, Maria Isabel; Autophagy as an innate immunity response against pathogens: a Tango dance; John Wiley and Sons Inc; FEBS Letters; 598; 1; 12-2023; 140-166
1873-3468
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14788
info:eu-repo/semantics/altIdentifier/doi/10.1002/1873-3468.14788
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv John Wiley and Sons Inc
publisher.none.fl_str_mv John Wiley and Sons Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269437281959936
score 13.13397

Publicaciones similares