Experimental and numerical response of a passive glaucoma drainage device

Autores
Sassetti, Fernando; Garelli, Luciano; Guarnieri, Fabio Ariel
Año de publicación
2013
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Glaucoma is the optic nerve damage often associated with an increased intraocular pressure that leads to progressive and irreversible loss of vision. The Ahmed valve is a passive device constructed from two opposed deformable silicone elastomers sheets, commonly used for the regulation of intraocular pressure in patients with glaucoma. In this work the dynamic response of the Ahmed valve to different flow conditions and gravity test of FDA is analyzed. This is carried out by means of the numerical simulation using the Finite Element Method, considering a partitioned Fluid-Structure coupling between the fluid and the structure of the valve. The fluid is described by the incompressible Navier-Stokes equations, written in an arbitrary time dependent coordinate system and the structure is described by a constitutive linear elastic solid assuming large displacements and rotations. In order to decrease the computational cost of the simulation, a reduced order model of the system is also presented. This model is developed using data from a previous characterization process using the partitioned fluid-structure solver. With the aim to validate the numerical simulation, the results are compared with experimental ones.
Fil: Sassetti, Fernando. Universidad Nacional de Entre Rios. Facultad de Ingenieria. Departamento de Bioingenieria; Argentina
Fil: Garelli, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro de Investigación de Métodos Computacionales; Argentina
Fil: Guarnieri, Fabio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro de Investigación de Métodos Computacionales; Argentina
Materia
Glaucoma
Ahmed valve
Finite element method
Gravity flow test
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/8596
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/8596
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Experimental and numerical response of a passive glaucoma drainage deviceSassetti, FernandoGarelli, LucianoGuarnieri, Fabio ArielGlaucomaAhmed valveFinite element methodGravity flow testhttps://purl.org/becyt/ford/2.3https://purl.org/becyt/ford/2Glaucoma is the optic nerve damage often associated with an increased intraocular pressure that leads to progressive and irreversible loss of vision. The Ahmed valve is a passive device constructed from two opposed deformable silicone elastomers sheets, commonly used for the regulation of intraocular pressure in patients with glaucoma. In this work the dynamic response of the Ahmed valve to different flow conditions and gravity test of FDA is analyzed. This is carried out by means of the numerical simulation using the Finite Element Method, considering a partitioned Fluid-Structure coupling between the fluid and the structure of the valve. The fluid is described by the incompressible Navier-Stokes equations, written in an arbitrary time dependent coordinate system and the structure is described by a constitutive linear elastic solid assuming large displacements and rotations. In order to decrease the computational cost of the simulation, a reduced order model of the system is also presented. This model is developed using data from a previous characterization process using the partitioned fluid-structure solver. With the aim to validate the numerical simulation, the results are compared with experimental ones.Fil: Sassetti, Fernando. Universidad Nacional de Entre Rios. Facultad de Ingenieria. Departamento de Bioingenieria; ArgentinaFil: Garelli, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro de Investigación de Métodos Computacionales; ArgentinaFil: Guarnieri, Fabio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro de Investigación de Métodos Computacionales; ArgentinaAsociación Argentina de Mecánica Computacional2013-11-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8596Sassetti, Fernando; Garelli, Luciano; Guarnieri, Fabio Ariel; Experimental and numerical response of a passive glaucoma drainage device; Asociación Argentina de Mecánica Computacional; Mecanica Computacional; XXXII; 44; 19-11-2013; 3861-38741666-6070spainfo:eu-repo/semantics/altIdentifier/url/http://www.cimec.org.ar/ojs/index.php/mc/article/view/4589info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:12:28Zoai:ri.conicet.gov.ar:11336/8596instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:12:28.405CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Experimental and numerical response of a passive glaucoma drainage device
title Experimental and numerical response of a passive glaucoma drainage device
spellingShingle Experimental and numerical response of a passive glaucoma drainage device
Sassetti, Fernando
Glaucoma
Ahmed valve
Finite element method
Gravity flow test
title_short Experimental and numerical response of a passive glaucoma drainage device
title_full Experimental and numerical response of a passive glaucoma drainage device
title_fullStr Experimental and numerical response of a passive glaucoma drainage device
title_full_unstemmed Experimental and numerical response of a passive glaucoma drainage device
title_sort Experimental and numerical response of a passive glaucoma drainage device
dc.creator.none.fl_str_mv Sassetti, Fernando
Garelli, Luciano
Guarnieri, Fabio Ariel
author Sassetti, Fernando
author_facet Sassetti, Fernando
Garelli, Luciano
Guarnieri, Fabio Ariel
author_role author
author2 Garelli, Luciano
Guarnieri, Fabio Ariel
author2_role author
author
dc.subject.none.fl_str_mv Glaucoma
Ahmed valve
Finite element method
Gravity flow test
topic Glaucoma
Ahmed valve
Finite element method
Gravity flow test
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.3
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Glaucoma is the optic nerve damage often associated with an increased intraocular pressure that leads to progressive and irreversible loss of vision. The Ahmed valve is a passive device constructed from two opposed deformable silicone elastomers sheets, commonly used for the regulation of intraocular pressure in patients with glaucoma. In this work the dynamic response of the Ahmed valve to different flow conditions and gravity test of FDA is analyzed. This is carried out by means of the numerical simulation using the Finite Element Method, considering a partitioned Fluid-Structure coupling between the fluid and the structure of the valve. The fluid is described by the incompressible Navier-Stokes equations, written in an arbitrary time dependent coordinate system and the structure is described by a constitutive linear elastic solid assuming large displacements and rotations. In order to decrease the computational cost of the simulation, a reduced order model of the system is also presented. This model is developed using data from a previous characterization process using the partitioned fluid-structure solver. With the aim to validate the numerical simulation, the results are compared with experimental ones.
Fil: Sassetti, Fernando. Universidad Nacional de Entre Rios. Facultad de Ingenieria. Departamento de Bioingenieria; Argentina
Fil: Garelli, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro de Investigación de Métodos Computacionales; Argentina
Fil: Guarnieri, Fabio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro de Investigación de Métodos Computacionales; Argentina
description Glaucoma is the optic nerve damage often associated with an increased intraocular pressure that leads to progressive and irreversible loss of vision. The Ahmed valve is a passive device constructed from two opposed deformable silicone elastomers sheets, commonly used for the regulation of intraocular pressure in patients with glaucoma. In this work the dynamic response of the Ahmed valve to different flow conditions and gravity test of FDA is analyzed. This is carried out by means of the numerical simulation using the Finite Element Method, considering a partitioned Fluid-Structure coupling between the fluid and the structure of the valve. The fluid is described by the incompressible Navier-Stokes equations, written in an arbitrary time dependent coordinate system and the structure is described by a constitutive linear elastic solid assuming large displacements and rotations. In order to decrease the computational cost of the simulation, a reduced order model of the system is also presented. This model is developed using data from a previous characterization process using the partitioned fluid-structure solver. With the aim to validate the numerical simulation, the results are compared with experimental ones.
publishDate 2013
dc.date.none.fl_str_mv 2013-11-19
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/8596
Sassetti, Fernando; Garelli, Luciano; Guarnieri, Fabio Ariel; Experimental and numerical response of a passive glaucoma drainage device; Asociación Argentina de Mecánica Computacional; Mecanica Computacional; XXXII; 44; 19-11-2013; 3861-3874
1666-6070
url http://hdl.handle.net/11336/8596
identifier_str_mv Sassetti, Fernando; Garelli, Luciano; Guarnieri, Fabio Ariel; Experimental and numerical response of a passive glaucoma drainage device; Asociación Argentina de Mecánica Computacional; Mecanica Computacional; XXXII; 44; 19-11-2013; 3861-3874
1666-6070
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.cimec.org.ar/ojs/index.php/mc/article/view/4589
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Asociación Argentina de Mecánica Computacional
publisher.none.fl_str_mv Asociación Argentina de Mecánica Computacional
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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