5-Methylcoumaranones from Mutisia friesiana and their bioactivity

Autores
Viturro, Carmen Ines; de la Fuente, Juana Rosa; Maier, Marta Silvia
Año de publicación
2004
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana.
Fil: Viturro, Carmen Ines. Universidad Nacional de Jujuy. Facultad de Ingeniería; Argentina
Fil: de la Fuente, Juana Rosa. Universidad Nacional de Salta. Facultad de Ciencias Exactas; Argentina
Fil: Maier, Marta Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina
Materia
Mutisia friesiana
Bioactivity
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/85634
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling 5-Methylcoumaranones from Mutisia friesiana and their bioactivityViturro, Carmen Inesde la Fuente, Juana RosaMaier, Marta SilviaMutisia friesianaBioactivityhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana.Fil: Viturro, Carmen Ines. Universidad Nacional de Jujuy. Facultad de Ingeniería; ArgentinaFil: de la Fuente, Juana Rosa. Universidad Nacional de Salta. Facultad de Ciencias Exactas; ArgentinaFil: Maier, Marta Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; ArgentinaAmerican Chemical Society2004-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/85634Viturro, Carmen Ines; de la Fuente, Juana Rosa; Maier, Marta Silvia; 5-Methylcoumaranones from Mutisia friesiana and their bioactivity; American Chemical Society; Journal of Natural Products; 67; 5; 5-2004; 778-7820163-3864CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/np0304058info:eu-repo/semantics/altIdentifier/doi/10.1021/np0304058info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:56:05Zoai:ri.conicet.gov.ar:11336/85634instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:56:05.746CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
spellingShingle 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
Viturro, Carmen Ines
Mutisia friesiana
Bioactivity
title_short 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_full 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_fullStr 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_full_unstemmed 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_sort 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
dc.creator.none.fl_str_mv Viturro, Carmen Ines
de la Fuente, Juana Rosa
Maier, Marta Silvia
author Viturro, Carmen Ines
author_facet Viturro, Carmen Ines
de la Fuente, Juana Rosa
Maier, Marta Silvia
author_role author
author2 de la Fuente, Juana Rosa
Maier, Marta Silvia
author2_role author
author
dc.subject.none.fl_str_mv Mutisia friesiana
Bioactivity
topic Mutisia friesiana
Bioactivity
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana.
Fil: Viturro, Carmen Ines. Universidad Nacional de Jujuy. Facultad de Ingeniería; Argentina
Fil: de la Fuente, Juana Rosa. Universidad Nacional de Salta. Facultad de Ciencias Exactas; Argentina
Fil: Maier, Marta Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina
description In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana.
publishDate 2004
dc.date.none.fl_str_mv 2004-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/85634
Viturro, Carmen Ines; de la Fuente, Juana Rosa; Maier, Marta Silvia; 5-Methylcoumaranones from Mutisia friesiana and their bioactivity; American Chemical Society; Journal of Natural Products; 67; 5; 5-2004; 778-782
0163-3864
CONICET Digital
CONICET
url http://hdl.handle.net/11336/85634
identifier_str_mv Viturro, Carmen Ines; de la Fuente, Juana Rosa; Maier, Marta Silvia; 5-Methylcoumaranones from Mutisia friesiana and their bioactivity; American Chemical Society; Journal of Natural Products; 67; 5; 5-2004; 778-782
0163-3864
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/np0304058
info:eu-repo/semantics/altIdentifier/doi/10.1021/np0304058
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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