Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis

Autores
Neres Rodrigues, Diego Lucas; Rodrigues da Costa, Francielly Morais; Marques Da Silva, Wanderson; Aburjaile, Flavia; Azevedo, Vasco
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.
Fil: Neres Rodrigues, Diego Lucas. Universidade Federal de Minas Gerais; Brasil
Fil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais; Brasil
Fil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Aburjaile, Flavia. Universidade Federal de Minas Gerais; Brasil
Fil: Azevedo, Vasco. Universidade Federal de Minas Gerais; Brasil
Materia
CRAB
INFECTION
RESISTOME
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/213793
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-AnalysisNeres Rodrigues, Diego LucasRodrigues da Costa, Francielly MoraisMarques Da Silva, WandersonAburjaile, FlaviaAzevedo, VascoCRABINFECTIONRESISTOMEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.Fil: Neres Rodrigues, Diego Lucas. Universidade Federal de Minas Gerais; BrasilFil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais; BrasilFil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Aburjaile, Flavia. Universidade Federal de Minas Gerais; BrasilFil: Azevedo, Vasco. Universidade Federal de Minas Gerais; BrasilMultidisciplinary Digital Publishing Institute2022-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/213793Neres Rodrigues, Diego Lucas; Rodrigues da Costa, Francielly Morais; Marques Da Silva, Wanderson; Aburjaile, Flavia; Azevedo, Vasco; Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis; Multidisciplinary Digital Publishing Institute; Bacteria; 1; 2; 5-2022; 112-1202674-1334CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2674-1334/1/2/10info:eu-repo/semantics/altIdentifier/doi/10.3390/bacteria1020010info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:11:12Zoai:ri.conicet.gov.ar:11336/213793instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:11:12.269CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
title Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
spellingShingle Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
Neres Rodrigues, Diego Lucas
CRAB
INFECTION
RESISTOME
title_short Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
title_full Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
title_fullStr Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
title_full_unstemmed Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
title_sort Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis
dc.creator.none.fl_str_mv Neres Rodrigues, Diego Lucas
Rodrigues da Costa, Francielly Morais
Marques Da Silva, Wanderson
Aburjaile, Flavia
Azevedo, Vasco
author Neres Rodrigues, Diego Lucas
author_facet Neres Rodrigues, Diego Lucas
Rodrigues da Costa, Francielly Morais
Marques Da Silva, Wanderson
Aburjaile, Flavia
Azevedo, Vasco
author_role author
author2 Rodrigues da Costa, Francielly Morais
Marques Da Silva, Wanderson
Aburjaile, Flavia
Azevedo, Vasco
author2_role author
author
author
author
dc.subject.none.fl_str_mv CRAB
INFECTION
RESISTOME
topic CRAB
INFECTION
RESISTOME
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.
Fil: Neres Rodrigues, Diego Lucas. Universidade Federal de Minas Gerais; Brasil
Fil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais; Brasil
Fil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Agrobiotecnología y Biología Molecular. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Aburjaile, Flavia. Universidade Federal de Minas Gerais; Brasil
Fil: Azevedo, Vasco. Universidade Federal de Minas Gerais; Brasil
description Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem.
publishDate 2022
dc.date.none.fl_str_mv 2022-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/213793
Neres Rodrigues, Diego Lucas; Rodrigues da Costa, Francielly Morais; Marques Da Silva, Wanderson; Aburjaile, Flavia; Azevedo, Vasco; Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis; Multidisciplinary Digital Publishing Institute; Bacteria; 1; 2; 5-2022; 112-120
2674-1334
CONICET Digital
CONICET
url http://hdl.handle.net/11336/213793
identifier_str_mv Neres Rodrigues, Diego Lucas; Rodrigues da Costa, Francielly Morais; Marques Da Silva, Wanderson; Aburjaile, Flavia; Azevedo, Vasco; Acinetobacter baumannii and Its Relationship to Carbapenem Resistance: A Meta-Analysis; Multidisciplinary Digital Publishing Institute; Bacteria; 1; 2; 5-2022; 112-120
2674-1334
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2674-1334/1/2/10
info:eu-repo/semantics/altIdentifier/doi/10.3390/bacteria1020010
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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