Impaired mesial synchronization in temporal lobe epilepsy

Autores
Ortega, Guillermo José; Peco, Iván Herrera; Sola, Rafael G.; Pastor, Jesús
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objective: Temporal lobe epilepsy is commonly associated with synchronous, hyper-synchronous and des-synchronous activity. The aim of the present work is to explore synchronization activity in both mesial areas in temporal lobe epileptic patients during the interictal state. Methods: Using a cluster technique, we analyzed 17 temporal lobe epilepsy patients’ records of foramen ovale electrodes activity during the inter-ictal state. Results: There exists a clear tendency in the mesial area of the epileptic side to be organized as isolated clusters of electrical activity as compared with the contra-lateral side, which is organized in the form of large clusters of synchronous activity. The number of desynchronized areas is larger in the epileptic side than in the contra-lateral side in 16 out of 17 temporal lobe epileptic patients. Conclusions: The mesial area responsible for the seizures is less synchronous than the contra-lateral; the different kind of synchronous organization accounts for a lower synchronization activity at the epileptic side, suggesting that this lack of synchronous cluster organization would favour the appearance of seizures. Significance: Our results shed new light regarding synchronization issues in temporal lobe epilepsy and also it would help in reducing drastically the time of study.
Fil: Ortega, Guillermo José. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Peco, Iván Herrera. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España
Fil: Sola, Rafael G.. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España
Fil: Pastor, Jesús. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España
Materia
CLUSTERS
COMPLEXITY
FORAMEN OVALE ELECTRODES
SYNCHRONIZATION
TEMPORAL LOBE EPILEPSY
VIDEO-ELECTROENCEPHALOGRAPHY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/194671
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/194671
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Impaired mesial synchronization in temporal lobe epilepsyOrtega, Guillermo JoséPeco, Iván HerreraSola, Rafael G.Pastor, JesúsCLUSTERSCOMPLEXITYFORAMEN OVALE ELECTRODESSYNCHRONIZATIONTEMPORAL LOBE EPILEPSYVIDEO-ELECTROENCEPHALOGRAPHYhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Objective: Temporal lobe epilepsy is commonly associated with synchronous, hyper-synchronous and des-synchronous activity. The aim of the present work is to explore synchronization activity in both mesial areas in temporal lobe epileptic patients during the interictal state. Methods: Using a cluster technique, we analyzed 17 temporal lobe epilepsy patients’ records of foramen ovale electrodes activity during the inter-ictal state. Results: There exists a clear tendency in the mesial area of the epileptic side to be organized as isolated clusters of electrical activity as compared with the contra-lateral side, which is organized in the form of large clusters of synchronous activity. The number of desynchronized areas is larger in the epileptic side than in the contra-lateral side in 16 out of 17 temporal lobe epileptic patients. Conclusions: The mesial area responsible for the seizures is less synchronous than the contra-lateral; the different kind of synchronous organization accounts for a lower synchronization activity at the epileptic side, suggesting that this lack of synchronous cluster organization would favour the appearance of seizures. Significance: Our results shed new light regarding synchronization issues in temporal lobe epilepsy and also it would help in reducing drastically the time of study.Fil: Ortega, Guillermo José. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Peco, Iván Herrera. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; EspañaFil: Sola, Rafael G.. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; EspañaFil: Pastor, Jesús. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; EspañaElsevier Ireland2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/194671Ortega, Guillermo José; Peco, Iván Herrera; Sola, Rafael G.; Pastor, Jesús; Impaired mesial synchronization in temporal lobe epilepsy; Elsevier Ireland; Clinical Neurophysiology; 122; 6; 12-2011; 1106-11161388-2457CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1388245710007856info:eu-repo/semantics/altIdentifier/doi/10.1016/j.clinph.2010.11.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:04:06Zoai:ri.conicet.gov.ar:11336/194671instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:04:06.909CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Impaired mesial synchronization in temporal lobe epilepsy
title Impaired mesial synchronization in temporal lobe epilepsy
spellingShingle Impaired mesial synchronization in temporal lobe epilepsy
Ortega, Guillermo José
CLUSTERS
COMPLEXITY
FORAMEN OVALE ELECTRODES
SYNCHRONIZATION
TEMPORAL LOBE EPILEPSY
VIDEO-ELECTROENCEPHALOGRAPHY
title_short Impaired mesial synchronization in temporal lobe epilepsy
title_full Impaired mesial synchronization in temporal lobe epilepsy
title_fullStr Impaired mesial synchronization in temporal lobe epilepsy
title_full_unstemmed Impaired mesial synchronization in temporal lobe epilepsy
title_sort Impaired mesial synchronization in temporal lobe epilepsy
dc.creator.none.fl_str_mv Ortega, Guillermo José
Peco, Iván Herrera
Sola, Rafael G.
Pastor, Jesús
author Ortega, Guillermo José
author_facet Ortega, Guillermo José
Peco, Iván Herrera
Sola, Rafael G.
Pastor, Jesús
author_role author
author2 Peco, Iván Herrera
Sola, Rafael G.
Pastor, Jesús
author2_role author
author
author
dc.subject.none.fl_str_mv CLUSTERS
COMPLEXITY
FORAMEN OVALE ELECTRODES
SYNCHRONIZATION
TEMPORAL LOBE EPILEPSY
VIDEO-ELECTROENCEPHALOGRAPHY
topic CLUSTERS
COMPLEXITY
FORAMEN OVALE ELECTRODES
SYNCHRONIZATION
TEMPORAL LOBE EPILEPSY
VIDEO-ELECTROENCEPHALOGRAPHY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Objective: Temporal lobe epilepsy is commonly associated with synchronous, hyper-synchronous and des-synchronous activity. The aim of the present work is to explore synchronization activity in both mesial areas in temporal lobe epileptic patients during the interictal state. Methods: Using a cluster technique, we analyzed 17 temporal lobe epilepsy patients’ records of foramen ovale electrodes activity during the inter-ictal state. Results: There exists a clear tendency in the mesial area of the epileptic side to be organized as isolated clusters of electrical activity as compared with the contra-lateral side, which is organized in the form of large clusters of synchronous activity. The number of desynchronized areas is larger in the epileptic side than in the contra-lateral side in 16 out of 17 temporal lobe epileptic patients. Conclusions: The mesial area responsible for the seizures is less synchronous than the contra-lateral; the different kind of synchronous organization accounts for a lower synchronization activity at the epileptic side, suggesting that this lack of synchronous cluster organization would favour the appearance of seizures. Significance: Our results shed new light regarding synchronization issues in temporal lobe epilepsy and also it would help in reducing drastically the time of study.
Fil: Ortega, Guillermo José. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Peco, Iván Herrera. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España
Fil: Sola, Rafael G.. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España
Fil: Pastor, Jesús. Universidad Autonoma de Madrid. Hospital Universitario de la Princesa; España
description Objective: Temporal lobe epilepsy is commonly associated with synchronous, hyper-synchronous and des-synchronous activity. The aim of the present work is to explore synchronization activity in both mesial areas in temporal lobe epileptic patients during the interictal state. Methods: Using a cluster technique, we analyzed 17 temporal lobe epilepsy patients’ records of foramen ovale electrodes activity during the inter-ictal state. Results: There exists a clear tendency in the mesial area of the epileptic side to be organized as isolated clusters of electrical activity as compared with the contra-lateral side, which is organized in the form of large clusters of synchronous activity. The number of desynchronized areas is larger in the epileptic side than in the contra-lateral side in 16 out of 17 temporal lobe epileptic patients. Conclusions: The mesial area responsible for the seizures is less synchronous than the contra-lateral; the different kind of synchronous organization accounts for a lower synchronization activity at the epileptic side, suggesting that this lack of synchronous cluster organization would favour the appearance of seizures. Significance: Our results shed new light regarding synchronization issues in temporal lobe epilepsy and also it would help in reducing drastically the time of study.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/194671
Ortega, Guillermo José; Peco, Iván Herrera; Sola, Rafael G.; Pastor, Jesús; Impaired mesial synchronization in temporal lobe epilepsy; Elsevier Ireland; Clinical Neurophysiology; 122; 6; 12-2011; 1106-1116
1388-2457
CONICET Digital
CONICET
url http://hdl.handle.net/11336/194671
identifier_str_mv Ortega, Guillermo José; Peco, Iván Herrera; Sola, Rafael G.; Pastor, Jesús; Impaired mesial synchronization in temporal lobe epilepsy; Elsevier Ireland; Clinical Neurophysiology; 122; 6; 12-2011; 1106-1116
1388-2457
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1388245710007856
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.clinph.2010.11.001
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Ireland
publisher.none.fl_str_mv Elsevier Ireland
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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