Antidepressants: Influence on cancer and immunity?

Autores
Frick, Luciana Romina; Rapanelli, Maximiliano
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Two decades ago, it was hypothesized that antidepressants could alter the course of neoplastic diseases. However, contradictory findings indicated that antidepressants could either have carcinogenic properties or improve the disease outcome. Intriguingly, controversial results were reported on the action of antidepressant drugs on immune function. Further hypotheses proposed that antidepressants could indirectly affect the cancer prognosis through the modulation of antitumor activity. Here we review the literature in order to elucidate the influence of antidepressants on cancer and immunity.
Fil: Frick, Luciana Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Rapanelli, Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Materia
ANTIDEPRESSANT
APOPTOSIS
CANCER
CYTOKINES
CYTOTOXICITY
FLUOXETINE
IMMUNITY
TUMOR PROLIFERATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/2465

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network_name_str CONICET Digital (CONICET)
spelling Antidepressants: Influence on cancer and immunity?Frick, Luciana RominaRapanelli, MaximilianoANTIDEPRESSANTAPOPTOSISCANCERCYTOKINESCYTOTOXICITYFLUOXETINEIMMUNITYTUMOR PROLIFERATIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Two decades ago, it was hypothesized that antidepressants could alter the course of neoplastic diseases. However, contradictory findings indicated that antidepressants could either have carcinogenic properties or improve the disease outcome. Intriguingly, controversial results were reported on the action of antidepressant drugs on immune function. Further hypotheses proposed that antidepressants could indirectly affect the cancer prognosis through the modulation of antitumor activity. Here we review the literature in order to elucidate the influence of antidepressants on cancer and immunity.Fil: Frick, Luciana Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Rapanelli, Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaElsevier2013-01-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/2465Frick, Luciana Romina; Rapanelli, Maximiliano; Antidepressants: Influence on cancer and immunity?; Elsevier; Life Sciences; 92; 10; 28-1-2013; 525-5320024-32051879-0631enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.lfs.2013.01.020info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0024320513000489info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:58:58Zoai:ri.conicet.gov.ar:11336/2465instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:58:58.594CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antidepressants: Influence on cancer and immunity?
title Antidepressants: Influence on cancer and immunity?
spellingShingle Antidepressants: Influence on cancer and immunity?
Frick, Luciana Romina
ANTIDEPRESSANT
APOPTOSIS
CANCER
CYTOKINES
CYTOTOXICITY
FLUOXETINE
IMMUNITY
TUMOR PROLIFERATION
title_short Antidepressants: Influence on cancer and immunity?
title_full Antidepressants: Influence on cancer and immunity?
title_fullStr Antidepressants: Influence on cancer and immunity?
title_full_unstemmed Antidepressants: Influence on cancer and immunity?
title_sort Antidepressants: Influence on cancer and immunity?
dc.creator.none.fl_str_mv Frick, Luciana Romina
Rapanelli, Maximiliano
author Frick, Luciana Romina
author_facet Frick, Luciana Romina
Rapanelli, Maximiliano
author_role author
author2 Rapanelli, Maximiliano
author2_role author
dc.subject.none.fl_str_mv ANTIDEPRESSANT
APOPTOSIS
CANCER
CYTOKINES
CYTOTOXICITY
FLUOXETINE
IMMUNITY
TUMOR PROLIFERATION
topic ANTIDEPRESSANT
APOPTOSIS
CANCER
CYTOKINES
CYTOTOXICITY
FLUOXETINE
IMMUNITY
TUMOR PROLIFERATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Two decades ago, it was hypothesized that antidepressants could alter the course of neoplastic diseases. However, contradictory findings indicated that antidepressants could either have carcinogenic properties or improve the disease outcome. Intriguingly, controversial results were reported on the action of antidepressant drugs on immune function. Further hypotheses proposed that antidepressants could indirectly affect the cancer prognosis through the modulation of antitumor activity. Here we review the literature in order to elucidate the influence of antidepressants on cancer and immunity.
Fil: Frick, Luciana Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Rapanelli, Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
description Two decades ago, it was hypothesized that antidepressants could alter the course of neoplastic diseases. However, contradictory findings indicated that antidepressants could either have carcinogenic properties or improve the disease outcome. Intriguingly, controversial results were reported on the action of antidepressant drugs on immune function. Further hypotheses proposed that antidepressants could indirectly affect the cancer prognosis through the modulation of antitumor activity. Here we review the literature in order to elucidate the influence of antidepressants on cancer and immunity.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-28
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/2465
Frick, Luciana Romina; Rapanelli, Maximiliano; Antidepressants: Influence on cancer and immunity?; Elsevier; Life Sciences; 92; 10; 28-1-2013; 525-532
0024-3205
1879-0631
url http://hdl.handle.net/11336/2465
identifier_str_mv Frick, Luciana Romina; Rapanelli, Maximiliano; Antidepressants: Influence on cancer and immunity?; Elsevier; Life Sciences; 92; 10; 28-1-2013; 525-532
0024-3205
1879-0631
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.lfs.2013.01.020
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0024320513000489
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432