Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells

Autores
Labovsky, Vivian; Martinez, Leandro Marcelo; Davies, Kevin Mauro; García Rivello, Hernán; Calcagno, María de Luján; Matas, Ayelen; Fernández Vallone, Valeria Beatriz; Wernicke, Alejandra; Choi, Hosoon; Chasseing, Norma Alejandra
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Despite advances in the study of breast cancer (BC), it remains the second leading cause of mortality among women. BC is a heterogeneous system, mainly composed of tumor epithelial cells (TEpCs) and stromal cells (SCs); the interaction through the ligands and their receptors (Rs) plays a major role in BC progression. The aim of the present study was to evaluate the association between ligands, such as osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), receptor activator of nuclear factor kappa B ligand (RANKL), stromal cell-derived factor (SDF)-1, interleukin (IL)-6, macrophage colony stimulating factor, chemokine (C-C motif) ligand-2 (CCL-2), and their Rs in TEpC and spindle-shaped SCs not closely associated with the vasculature.
Fil: Labovsky, Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Martinez, Leandro Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Davies, Kevin Mauro. Hospital Italiano de Buenos Aires; Argentina
Fil: García Rivello, Hernán. Hospital Italiano de Buenos Aires; Argentina
Fil: Calcagno, María de Luján. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Matas, Ayelen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Fernández Vallone, Valeria Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Wernicke, Alejandra. Hospital Italiano de Buenos Aires; Argentina
Fil: Choi, Hosoon. Institute for Regenerative Medicine at Scott & White. College of Medicine; Estados Unidos
Fil: Chasseing, Norma Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Materia
Breast Cancer
Tumor Epithelial Cells
Stromal Cells
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/10168
Acceder
id CONICETDig_dbad99e5331d16b4a652c84c87cb9468
oai_identifier_str oai:ri.conicet.gov.ar:11336/10168
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cellsLabovsky, VivianMartinez, Leandro MarceloDavies, Kevin MauroGarcía Rivello, HernánCalcagno, María de LujánMatas, AyelenFernández Vallone, Valeria BeatrizWernicke, AlejandraChoi, HosoonChasseing, Norma AlejandraBreast CancerTumor Epithelial CellsStromal Cellshttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Despite advances in the study of breast cancer (BC), it remains the second leading cause of mortality among women. BC is a heterogeneous system, mainly composed of tumor epithelial cells (TEpCs) and stromal cells (SCs); the interaction through the ligands and their receptors (Rs) plays a major role in BC progression. The aim of the present study was to evaluate the association between ligands, such as osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), receptor activator of nuclear factor kappa B ligand (RANKL), stromal cell-derived factor (SDF)-1, interleukin (IL)-6, macrophage colony stimulating factor, chemokine (C-C motif) ligand-2 (CCL-2), and their Rs in TEpC and spindle-shaped SCs not closely associated with the vasculature.Fil: Labovsky, Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Martinez, Leandro Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Davies, Kevin Mauro. Hospital Italiano de Buenos Aires; ArgentinaFil: García Rivello, Hernán. Hospital Italiano de Buenos Aires; ArgentinaFil: Calcagno, María de Luján. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Matas, Ayelen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Fernández Vallone, Valeria Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Wernicke, Alejandra. Hospital Italiano de Buenos Aires; ArgentinaFil: Choi, Hosoon. Institute for Regenerative Medicine at Scott & White. College of Medicine; Estados UnidosFil: Chasseing, Norma Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaElsevier2015-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/10168Labovsky, Vivian; Martinez, Leandro Marcelo; Davies, Kevin Mauro; García Rivello, Hernán; Calcagno, María de Luján; et al.; Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells; Elsevier; Clinical Breast Cancer; 15; 1; 2-2015; e13-e211526-82091938-0666enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.clbc.2014.05.006info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S152682091400113Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:43:55Zoai:ri.conicet.gov.ar:11336/10168instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:43:56.187CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
title Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
spellingShingle Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
Labovsky, Vivian
Breast Cancer
Tumor Epithelial Cells
Stromal Cells
title_short Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
title_full Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
title_fullStr Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
title_full_unstemmed Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
title_sort Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells
dc.creator.none.fl_str_mv Labovsky, Vivian
Martinez, Leandro Marcelo
Davies, Kevin Mauro
García Rivello, Hernán
Calcagno, María de Luján
Matas, Ayelen
Fernández Vallone, Valeria Beatriz
Wernicke, Alejandra
Choi, Hosoon
Chasseing, Norma Alejandra
author Labovsky, Vivian
author_facet Labovsky, Vivian
Martinez, Leandro Marcelo
Davies, Kevin Mauro
García Rivello, Hernán
Calcagno, María de Luján
Matas, Ayelen
Fernández Vallone, Valeria Beatriz
Wernicke, Alejandra
Choi, Hosoon
Chasseing, Norma Alejandra
author_role author
author2 Martinez, Leandro Marcelo
Davies, Kevin Mauro
García Rivello, Hernán
Calcagno, María de Luján
Matas, Ayelen
Fernández Vallone, Valeria Beatriz
Wernicke, Alejandra
Choi, Hosoon
Chasseing, Norma Alejandra
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Breast Cancer
Tumor Epithelial Cells
Stromal Cells
topic Breast Cancer
Tumor Epithelial Cells
Stromal Cells
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Despite advances in the study of breast cancer (BC), it remains the second leading cause of mortality among women. BC is a heterogeneous system, mainly composed of tumor epithelial cells (TEpCs) and stromal cells (SCs); the interaction through the ligands and their receptors (Rs) plays a major role in BC progression. The aim of the present study was to evaluate the association between ligands, such as osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), receptor activator of nuclear factor kappa B ligand (RANKL), stromal cell-derived factor (SDF)-1, interleukin (IL)-6, macrophage colony stimulating factor, chemokine (C-C motif) ligand-2 (CCL-2), and their Rs in TEpC and spindle-shaped SCs not closely associated with the vasculature.
Fil: Labovsky, Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Martinez, Leandro Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Davies, Kevin Mauro. Hospital Italiano de Buenos Aires; Argentina
Fil: García Rivello, Hernán. Hospital Italiano de Buenos Aires; Argentina
Fil: Calcagno, María de Luján. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Matas, Ayelen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Fernández Vallone, Valeria Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
Fil: Wernicke, Alejandra. Hospital Italiano de Buenos Aires; Argentina
Fil: Choi, Hosoon. Institute for Regenerative Medicine at Scott & White. College of Medicine; Estados Unidos
Fil: Chasseing, Norma Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina
description Despite advances in the study of breast cancer (BC), it remains the second leading cause of mortality among women. BC is a heterogeneous system, mainly composed of tumor epithelial cells (TEpCs) and stromal cells (SCs); the interaction through the ligands and their receptors (Rs) plays a major role in BC progression. The aim of the present study was to evaluate the association between ligands, such as osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), receptor activator of nuclear factor kappa B ligand (RANKL), stromal cell-derived factor (SDF)-1, interleukin (IL)-6, macrophage colony stimulating factor, chemokine (C-C motif) ligand-2 (CCL-2), and their Rs in TEpC and spindle-shaped SCs not closely associated with the vasculature.
publishDate 2015
dc.date.none.fl_str_mv 2015-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/10168
Labovsky, Vivian; Martinez, Leandro Marcelo; Davies, Kevin Mauro; García Rivello, Hernán; Calcagno, María de Luján; et al.; Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells; Elsevier; Clinical Breast Cancer; 15; 1; 2-2015; e13-e21
1526-8209
1938-0666
url http://hdl.handle.net/11336/10168
identifier_str_mv Labovsky, Vivian; Martinez, Leandro Marcelo; Davies, Kevin Mauro; García Rivello, Hernán; Calcagno, María de Luján; et al.; Association between of ligands and receptors related to the progression of early breast cancer in tumor epithelial and stromal cells; Elsevier; Clinical Breast Cancer; 15; 1; 2-2015; e13-e21
1526-8209
1938-0666
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.clbc.2014.05.006
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S152682091400113X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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