The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- prod...

Autores
Molehin, O. R.; Ajayi, Ebenezer Idowu O; Attah, A. F.; Awope, O. R.; Ige, E. T.; Omotoyinbo, O. E.; Aladetuyi, B. J.
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Medicinal plants have been shown to exert a plethora of biological and pharmacological which has been associated with the presence of several bioactive components. In this study, the effects of crude extracts of Citrullus lanatus seeds (CACL) and Chrysophyllum albidum cotyledons (CACA) on rat hepatocyte regeneration, liver cytochrome c oxidase activities, and their antimicrobial properties on a few bacteriocin-producing Gram-negative bacteria were determined. CACL and CACA were screened for the presence of amino acids using TLC sprayed with ninhydrin, pyridine and modified Commassie brilliant blue (G250). The amino acids were elucidated by Gas Chromatography-Mass Spectrometry (GC/MS) and Fourier-transform infrared spectroscopy (FTIR). CACA enhanced tissue regeneration in rat hepatocytes, in situ and increased the collagen content. CACA also enhanced the activity cytochrome c oxidase in the liver mitochondrial portion, but inhibited same in the homogenate. CACA and CACL did not inhibit the bacteriocin-producing bacteria at the different concentrations tested. It is evident that CACA and CACL contain amino acids that can improve liver antioxidant functions and its mitochondrial electron transport. Both amino acid-rich fractions, combined with bacteriocin may accelerate aseptic wound healing.
Fil: Molehin, O. R.. Ekiti State University; Nigeria
Fil: Ajayi, Ebenezer Idowu O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Osun State University. Department Of Biochemistry; Nigeria
Fil: Attah, A. F.. University of Ibadan; Nigeria
Fil: Awope, O. R.. Osun State University; Nigeria
Fil: Ige, E. T.. Ekiti State University; Nigeria
Fil: Omotoyinbo, O. E.. Ekiti State University; Nigeria
Fil: Aladetuyi, B. J.. Ekiti State University; Nigeria
Materia
Tissue regeneration
Catalase
Cytochrome c oxidase
Seed amino acids
Citrullus lanatus seeds
Chrysophyllum albidum cotyledons
Bacteriocin-producing bacteria
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/140262
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/140262
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteriaMolehin, O. R.Ajayi, Ebenezer Idowu OAttah, A. F.Awope, O. R.Ige, E. T.Omotoyinbo, O. E.Aladetuyi, B. J.Tissue regenerationCatalaseCytochrome c oxidaseSeed amino acidsCitrullus lanatus seedsChrysophyllum albidum cotyledonsBacteriocin-producing bacteriahttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Medicinal plants have been shown to exert a plethora of biological and pharmacological which has been associated with the presence of several bioactive components. In this study, the effects of crude extracts of Citrullus lanatus seeds (CACL) and Chrysophyllum albidum cotyledons (CACA) on rat hepatocyte regeneration, liver cytochrome c oxidase activities, and their antimicrobial properties on a few bacteriocin-producing Gram-negative bacteria were determined. CACL and CACA were screened for the presence of amino acids using TLC sprayed with ninhydrin, pyridine and modified Commassie brilliant blue (G250). The amino acids were elucidated by Gas Chromatography-Mass Spectrometry (GC/MS) and Fourier-transform infrared spectroscopy (FTIR). CACA enhanced tissue regeneration in rat hepatocytes, in situ and increased the collagen content. CACA also enhanced the activity cytochrome c oxidase in the liver mitochondrial portion, but inhibited same in the homogenate. CACA and CACL did not inhibit the bacteriocin-producing bacteria at the different concentrations tested. It is evident that CACA and CACL contain amino acids that can improve liver antioxidant functions and its mitochondrial electron transport. Both amino acid-rich fractions, combined with bacteriocin may accelerate aseptic wound healing.Fil: Molehin, O. R.. Ekiti State University; NigeriaFil: Ajayi, Ebenezer Idowu O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Osun State University. Department Of Biochemistry; NigeriaFil: Attah, A. F.. University of Ibadan; NigeriaFil: Awope, O. R.. Osun State University; NigeriaFil: Ige, E. T.. Ekiti State University; NigeriaFil: Omotoyinbo, O. E.. Ekiti State University; NigeriaFil: Aladetuyi, B. J.. Ekiti State University; NigeriaSocietà Italo-Latinoamericana di Etnomedicina2019-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/140262Molehin, O. R.; Ajayi, Ebenezer Idowu O; Attah, A. F.; Awope, O. R.; Ige, E. T.; et al.; The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria; Società Italo-Latinoamericana di Etnomedicina; Pharmacology Online; 3; 12-2019; 165-1841827-8620CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pharmacologyonline.silae.it/files/archives/2019/vol3/PhOL_2019_3_A015_Molehin.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:36:17Zoai:ri.conicet.gov.ar:11336/140262instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:36:17.503CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
title The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
spellingShingle The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
Molehin, O. R.
Tissue regeneration
Catalase
Cytochrome c oxidase
Seed amino acids
Citrullus lanatus seeds
Chrysophyllum albidum cotyledons
Bacteriocin-producing bacteria
title_short The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
title_full The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
title_fullStr The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
title_full_unstemmed The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
title_sort The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria
dc.creator.none.fl_str_mv Molehin, O. R.
Ajayi, Ebenezer Idowu O
Attah, A. F.
Awope, O. R.
Ige, E. T.
Omotoyinbo, O. E.
Aladetuyi, B. J.
author Molehin, O. R.
author_facet Molehin, O. R.
Ajayi, Ebenezer Idowu O
Attah, A. F.
Awope, O. R.
Ige, E. T.
Omotoyinbo, O. E.
Aladetuyi, B. J.
author_role author
author2 Ajayi, Ebenezer Idowu O
Attah, A. F.
Awope, O. R.
Ige, E. T.
Omotoyinbo, O. E.
Aladetuyi, B. J.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Tissue regeneration
Catalase
Cytochrome c oxidase
Seed amino acids
Citrullus lanatus seeds
Chrysophyllum albidum cotyledons
Bacteriocin-producing bacteria
topic Tissue regeneration
Catalase
Cytochrome c oxidase
Seed amino acids
Citrullus lanatus seeds
Chrysophyllum albidum cotyledons
Bacteriocin-producing bacteria
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Medicinal plants have been shown to exert a plethora of biological and pharmacological which has been associated with the presence of several bioactive components. In this study, the effects of crude extracts of Citrullus lanatus seeds (CACL) and Chrysophyllum albidum cotyledons (CACA) on rat hepatocyte regeneration, liver cytochrome c oxidase activities, and their antimicrobial properties on a few bacteriocin-producing Gram-negative bacteria were determined. CACL and CACA were screened for the presence of amino acids using TLC sprayed with ninhydrin, pyridine and modified Commassie brilliant blue (G250). The amino acids were elucidated by Gas Chromatography-Mass Spectrometry (GC/MS) and Fourier-transform infrared spectroscopy (FTIR). CACA enhanced tissue regeneration in rat hepatocytes, in situ and increased the collagen content. CACA also enhanced the activity cytochrome c oxidase in the liver mitochondrial portion, but inhibited same in the homogenate. CACA and CACL did not inhibit the bacteriocin-producing bacteria at the different concentrations tested. It is evident that CACA and CACL contain amino acids that can improve liver antioxidant functions and its mitochondrial electron transport. Both amino acid-rich fractions, combined with bacteriocin may accelerate aseptic wound healing.
Fil: Molehin, O. R.. Ekiti State University; Nigeria
Fil: Ajayi, Ebenezer Idowu O. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Osun State University. Department Of Biochemistry; Nigeria
Fil: Attah, A. F.. University of Ibadan; Nigeria
Fil: Awope, O. R.. Osun State University; Nigeria
Fil: Ige, E. T.. Ekiti State University; Nigeria
Fil: Omotoyinbo, O. E.. Ekiti State University; Nigeria
Fil: Aladetuyi, B. J.. Ekiti State University; Nigeria
description Medicinal plants have been shown to exert a plethora of biological and pharmacological which has been associated with the presence of several bioactive components. In this study, the effects of crude extracts of Citrullus lanatus seeds (CACL) and Chrysophyllum albidum cotyledons (CACA) on rat hepatocyte regeneration, liver cytochrome c oxidase activities, and their antimicrobial properties on a few bacteriocin-producing Gram-negative bacteria were determined. CACL and CACA were screened for the presence of amino acids using TLC sprayed with ninhydrin, pyridine and modified Commassie brilliant blue (G250). The amino acids were elucidated by Gas Chromatography-Mass Spectrometry (GC/MS) and Fourier-transform infrared spectroscopy (FTIR). CACA enhanced tissue regeneration in rat hepatocytes, in situ and increased the collagen content. CACA also enhanced the activity cytochrome c oxidase in the liver mitochondrial portion, but inhibited same in the homogenate. CACA and CACL did not inhibit the bacteriocin-producing bacteria at the different concentrations tested. It is evident that CACA and CACL contain amino acids that can improve liver antioxidant functions and its mitochondrial electron transport. Both amino acid-rich fractions, combined with bacteriocin may accelerate aseptic wound healing.
publishDate 2019
dc.date.none.fl_str_mv 2019-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/140262
Molehin, O. R.; Ajayi, Ebenezer Idowu O; Attah, A. F.; Awope, O. R.; Ige, E. T.; et al.; The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria; Società Italo-Latinoamericana di Etnomedicina; Pharmacology Online; 3; 12-2019; 165-184
1827-8620
CONICET Digital
CONICET
url http://hdl.handle.net/11336/140262
identifier_str_mv Molehin, O. R.; Ajayi, Ebenezer Idowu O; Attah, A. F.; Awope, O. R.; Ige, E. T.; et al.; The effects of solvent extracts of Citrulluslanatus seeds and Chrysophyllum albidum cotyledons on rat hepatocyte regeneration, cytochrome c oxidase activities and bacteriocin- producing gram-negative bacteria; Società Italo-Latinoamericana di Etnomedicina; Pharmacology Online; 3; 12-2019; 165-184
1827-8620
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pharmacologyonline.silae.it/files/archives/2019/vol3/PhOL_2019_3_A015_Molehin.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Società Italo-Latinoamericana di Etnomedicina
publisher.none.fl_str_mv Società Italo-Latinoamericana di Etnomedicina
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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