Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines

Autores
Muñoz, Mercedes; Pasquale, Gustavo; Sathicq, Angel Gabriel; Romanelli, Gustavo Pablo; Cabello, Carmen Ines; Gazzoli, Delia
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The volcanic ash from the Andes mountain range (Puyehue-Cordon Caulle volcanic complex situated in western South America on the Argentinean-Chilean border) was used as heterogeneous acid catalyst in the suitable synthesis of 3H-1,5-benzodiazepines. The natural ashes were classified according to their particle size to generate the different catalytic materials. The catalysts were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS), vibrational spectroscopies (FT-IR and Raman), and textural properties were determined by N2 adsorption (SBET). Potentiometric titration with n-butylamine was used to determine the acidic properties of the catalytic materials. Several 3H-1,5-benzodiazepines were obtained by reaction of o-phenylenediamine and substituted 1,3-diphenyl-1,3-propanedione in solvent-free conditions, giving good to excellent yields of a variety benzodiazepines. The method was carried out in environmentally friendly conditions and it was operationally simple. The volcanic ash resulted in a safe and recyclable catalyst.
Fil: Muñoz, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
Fil: Pasquale, Gustavo. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Centro de Investigacion En Sanidad Vegetal.; Argentina
Fil: Sathicq, Angel Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Centro de Investigacion En Sanidad Vegetal.; Argentina
Fil: Cabello, Carmen Ines. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Gazzoli, Delia. Università di Roma; Italia
Materia
BENZODIAZEPINES
GREEN CHEMISTRY
HETEROGENEOUS CATALYSIS
SOLVENT-FREE REACTION
VOLCANIC ASH
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/152051
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepinesMuñoz, MercedesPasquale, GustavoSathicq, Angel GabrielRomanelli, Gustavo PabloCabello, Carmen InesGazzoli, DeliaBENZODIAZEPINESGREEN CHEMISTRYHETEROGENEOUS CATALYSISSOLVENT-FREE REACTIONVOLCANIC ASHhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The volcanic ash from the Andes mountain range (Puyehue-Cordon Caulle volcanic complex situated in western South America on the Argentinean-Chilean border) was used as heterogeneous acid catalyst in the suitable synthesis of 3H-1,5-benzodiazepines. The natural ashes were classified according to their particle size to generate the different catalytic materials. The catalysts were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS), vibrational spectroscopies (FT-IR and Raman), and textural properties were determined by N2 adsorption (SBET). Potentiometric titration with n-butylamine was used to determine the acidic properties of the catalytic materials. Several 3H-1,5-benzodiazepines were obtained by reaction of o-phenylenediamine and substituted 1,3-diphenyl-1,3-propanedione in solvent-free conditions, giving good to excellent yields of a variety benzodiazepines. The method was carried out in environmentally friendly conditions and it was operationally simple. The volcanic ash resulted in a safe and recyclable catalyst.Fil: Muñoz, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; ArgentinaFil: Pasquale, Gustavo. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Centro de Investigacion En Sanidad Vegetal.; ArgentinaFil: Sathicq, Angel Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; ArgentinaFil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Centro de Investigacion En Sanidad Vegetal.; ArgentinaFil: Cabello, Carmen Ines. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; ArgentinaFil: Gazzoli, Delia. Università di Roma; ItaliaWalter de Gruyter GmbH2019-01-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/152051Muñoz, Mercedes; Pasquale, Gustavo; Sathicq, Angel Gabriel; Romanelli, Gustavo Pablo; Cabello, Carmen Ines; et al.; Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines; Walter de Gruyter GmbH; Green Processing and Synthesis; 8; 1; 28-1-2019; 600-6102191-95422191-9550CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1515/gps-2019-0030info:eu-repo/semantics/altIdentifier/url/https://www.degruyter.com/document/doi/10.1515/gps-2019-0030/htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T09:51:36Zoai:ri.conicet.gov.ar:11336/152051instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 09:51:36.619CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
title Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
spellingShingle Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
Muñoz, Mercedes
BENZODIAZEPINES
GREEN CHEMISTRY
HETEROGENEOUS CATALYSIS
SOLVENT-FREE REACTION
VOLCANIC ASH
title_short Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
title_full Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
title_fullStr Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
title_full_unstemmed Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
title_sort Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines
dc.creator.none.fl_str_mv Muñoz, Mercedes
Pasquale, Gustavo
Sathicq, Angel Gabriel
Romanelli, Gustavo Pablo
Cabello, Carmen Ines
Gazzoli, Delia
author Muñoz, Mercedes
author_facet Muñoz, Mercedes
Pasquale, Gustavo
Sathicq, Angel Gabriel
Romanelli, Gustavo Pablo
Cabello, Carmen Ines
Gazzoli, Delia
author_role author
author2 Pasquale, Gustavo
Sathicq, Angel Gabriel
Romanelli, Gustavo Pablo
Cabello, Carmen Ines
Gazzoli, Delia
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv BENZODIAZEPINES
GREEN CHEMISTRY
HETEROGENEOUS CATALYSIS
SOLVENT-FREE REACTION
VOLCANIC ASH
topic BENZODIAZEPINES
GREEN CHEMISTRY
HETEROGENEOUS CATALYSIS
SOLVENT-FREE REACTION
VOLCANIC ASH
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The volcanic ash from the Andes mountain range (Puyehue-Cordon Caulle volcanic complex situated in western South America on the Argentinean-Chilean border) was used as heterogeneous acid catalyst in the suitable synthesis of 3H-1,5-benzodiazepines. The natural ashes were classified according to their particle size to generate the different catalytic materials. The catalysts were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS), vibrational spectroscopies (FT-IR and Raman), and textural properties were determined by N2 adsorption (SBET). Potentiometric titration with n-butylamine was used to determine the acidic properties of the catalytic materials. Several 3H-1,5-benzodiazepines were obtained by reaction of o-phenylenediamine and substituted 1,3-diphenyl-1,3-propanedione in solvent-free conditions, giving good to excellent yields of a variety benzodiazepines. The method was carried out in environmentally friendly conditions and it was operationally simple. The volcanic ash resulted in a safe and recyclable catalyst.
Fil: Muñoz, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
Fil: Pasquale, Gustavo. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Centro de Investigacion En Sanidad Vegetal.; Argentina
Fil: Sathicq, Angel Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina. Universidad Nacional de la Plata. Facultad de Cs.agrarias y Forestales. Centro de Investigacion En Sanidad Vegetal.; Argentina
Fil: Cabello, Carmen Ines. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas; Argentina
Fil: Gazzoli, Delia. Università di Roma; Italia
description The volcanic ash from the Andes mountain range (Puyehue-Cordon Caulle volcanic complex situated in western South America on the Argentinean-Chilean border) was used as heterogeneous acid catalyst in the suitable synthesis of 3H-1,5-benzodiazepines. The natural ashes were classified according to their particle size to generate the different catalytic materials. The catalysts were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS), vibrational spectroscopies (FT-IR and Raman), and textural properties were determined by N2 adsorption (SBET). Potentiometric titration with n-butylamine was used to determine the acidic properties of the catalytic materials. Several 3H-1,5-benzodiazepines were obtained by reaction of o-phenylenediamine and substituted 1,3-diphenyl-1,3-propanedione in solvent-free conditions, giving good to excellent yields of a variety benzodiazepines. The method was carried out in environmentally friendly conditions and it was operationally simple. The volcanic ash resulted in a safe and recyclable catalyst.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-28
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/152051
Muñoz, Mercedes; Pasquale, Gustavo; Sathicq, Angel Gabriel; Romanelli, Gustavo Pablo; Cabello, Carmen Ines; et al.; Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines; Walter de Gruyter GmbH; Green Processing and Synthesis; 8; 1; 28-1-2019; 600-610
2191-9542
2191-9550
CONICET Digital
CONICET
url http://hdl.handle.net/11336/152051
identifier_str_mv Muñoz, Mercedes; Pasquale, Gustavo; Sathicq, Angel Gabriel; Romanelli, Gustavo Pablo; Cabello, Carmen Ines; et al.; Volcanic ash as reusable catalyst in the green synthesis of 3H-1,5-benzodiazepines; Walter de Gruyter GmbH; Green Processing and Synthesis; 8; 1; 28-1-2019; 600-610
2191-9542
2191-9550
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1515/gps-2019-0030
info:eu-repo/semantics/altIdentifier/url/https://www.degruyter.com/document/doi/10.1515/gps-2019-0030/html
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Walter de Gruyter GmbH
publisher.none.fl_str_mv Walter de Gruyter GmbH
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.084122

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