Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents

Autores
Cuggino, Julio César; Alvarez Igarzabal, Cecilia Ines; Rueda, Juan Carlos; Quinzani, Lidia Maria; Komber, Kartmurt; Strumia, Miriam Cristina
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In this study, new hydrogels in rod shape were prepared from N-acryloyl-tris-(hydroxymethyl) aminomethane (NAT) using three different crosslinking agents: poly(2-methyl-2-oxazoline) bismacromonomer (BM), ethylene glycol dimethacrylate (EGDMA) and N,N´-methylenebisacrylamide (BIS). Dimethylformamide (DMF) was used as solvent and 2,2´-azobisisobutyronitrile (AIBN) as initiator. Polymeric matrices with different properties were obtained by free radical polymerization by changing the crosslinker (BM, EGDMA or BIS) or the concentration of BM. The hydrogel structures were characterized by high resolution magic angle spinning (HRMAS) NMR technique. Swelling experiments and rheological studies were used to test the water absorption capacity and viscoelastic properties of the hydrogels, respectively. For a given NAT/crosslinking agent molar ratio, the hydrogel synthesized with BM displays higher water absorptive capacity and larger range of linear viscoelasticity than those synthesized with BIS or EGDMA. The relatively larger hydrophilic character of the former and the lower crosslinking density generated by the longer molecules of BM might be the cause of this behavior. The results also reveal that water diffuses into the network following a non-Fickian mechanism. This is concluded from the value of the diffusion exponent n, which is higher than 0.50. The elastic modulus and the equilibrium water content (EWC) measurements suggest that these materials may have potential application as biomaterials.
Fil: Cuggino, Julio César. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Alvarez Igarzabal, Cecilia Ines. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rueda, Juan Carlos. Universidad Nacional de Córdoba; Argentina
Fil: Quinzani, Lidia Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Komber, Kartmurt. Universidad Nacional de Córdoba; Argentina
Fil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Hydrogel
Crosslinking
Diffusion
Rheology
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/25352
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/25352
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking AgentsCuggino, Julio CésarAlvarez Igarzabal, Cecilia InesRueda, Juan CarlosQuinzani, Lidia MariaKomber, KartmurtStrumia, Miriam CristinaHydrogelCrosslinkingDiffusionRheologyhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2In this study, new hydrogels in rod shape were prepared from N-acryloyl-tris-(hydroxymethyl) aminomethane (NAT) using three different crosslinking agents: poly(2-methyl-2-oxazoline) bismacromonomer (BM), ethylene glycol dimethacrylate (EGDMA) and N,N´-methylenebisacrylamide (BIS). Dimethylformamide (DMF) was used as solvent and 2,2´-azobisisobutyronitrile (AIBN) as initiator. Polymeric matrices with different properties were obtained by free radical polymerization by changing the crosslinker (BM, EGDMA or BIS) or the concentration of BM. The hydrogel structures were characterized by high resolution magic angle spinning (HRMAS) NMR technique. Swelling experiments and rheological studies were used to test the water absorption capacity and viscoelastic properties of the hydrogels, respectively. For a given NAT/crosslinking agent molar ratio, the hydrogel synthesized with BM displays higher water absorptive capacity and larger range of linear viscoelasticity than those synthesized with BIS or EGDMA. The relatively larger hydrophilic character of the former and the lower crosslinking density generated by the longer molecules of BM might be the cause of this behavior. The results also reveal that water diffuses into the network following a non-Fickian mechanism. This is concluded from the value of the diffusion exponent n, which is higher than 0.50. The elastic modulus and the equilibrium water content (EWC) measurements suggest that these materials may have potential application as biomaterials.Fil: Cuggino, Julio César. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Alvarez Igarzabal, Cecilia Ines. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rueda, Juan Carlos. Universidad Nacional de Córdoba; ArgentinaFil: Quinzani, Lidia Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Komber, Kartmurt. Universidad Nacional de Córdoba; ArgentinaFil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2008-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/25352Cuggino, Julio César; Alvarez Igarzabal, Cecilia Ines; Rueda, Juan Carlos; Quinzani, Lidia Maria; Komber, Kartmurt; et al.; Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents; Elsevier; European Polymer Journal; 44; 11; 12-2008; 3548-35550014-3057CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.eurpolymj.2008.09.010info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0014305708004709info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:22:44Zoai:ri.conicet.gov.ar:11336/25352instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:22:45.303CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
title Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
spellingShingle Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
Cuggino, Julio César
Hydrogel
Crosslinking
Diffusion
Rheology
title_short Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
title_full Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
title_fullStr Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
title_full_unstemmed Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
title_sort Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents
dc.creator.none.fl_str_mv Cuggino, Julio César
Alvarez Igarzabal, Cecilia Ines
Rueda, Juan Carlos
Quinzani, Lidia Maria
Komber, Kartmurt
Strumia, Miriam Cristina
author Cuggino, Julio César
author_facet Cuggino, Julio César
Alvarez Igarzabal, Cecilia Ines
Rueda, Juan Carlos
Quinzani, Lidia Maria
Komber, Kartmurt
Strumia, Miriam Cristina
author_role author
author2 Alvarez Igarzabal, Cecilia Ines
Rueda, Juan Carlos
Quinzani, Lidia Maria
Komber, Kartmurt
Strumia, Miriam Cristina
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Hydrogel
Crosslinking
Diffusion
Rheology
topic Hydrogel
Crosslinking
Diffusion
Rheology
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In this study, new hydrogels in rod shape were prepared from N-acryloyl-tris-(hydroxymethyl) aminomethane (NAT) using three different crosslinking agents: poly(2-methyl-2-oxazoline) bismacromonomer (BM), ethylene glycol dimethacrylate (EGDMA) and N,N´-methylenebisacrylamide (BIS). Dimethylformamide (DMF) was used as solvent and 2,2´-azobisisobutyronitrile (AIBN) as initiator. Polymeric matrices with different properties were obtained by free radical polymerization by changing the crosslinker (BM, EGDMA or BIS) or the concentration of BM. The hydrogel structures were characterized by high resolution magic angle spinning (HRMAS) NMR technique. Swelling experiments and rheological studies were used to test the water absorption capacity and viscoelastic properties of the hydrogels, respectively. For a given NAT/crosslinking agent molar ratio, the hydrogel synthesized with BM displays higher water absorptive capacity and larger range of linear viscoelasticity than those synthesized with BIS or EGDMA. The relatively larger hydrophilic character of the former and the lower crosslinking density generated by the longer molecules of BM might be the cause of this behavior. The results also reveal that water diffuses into the network following a non-Fickian mechanism. This is concluded from the value of the diffusion exponent n, which is higher than 0.50. The elastic modulus and the equilibrium water content (EWC) measurements suggest that these materials may have potential application as biomaterials.
Fil: Cuggino, Julio César. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Alvarez Igarzabal, Cecilia Ines. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rueda, Juan Carlos. Universidad Nacional de Córdoba; Argentina
Fil: Quinzani, Lidia Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Komber, Kartmurt. Universidad Nacional de Córdoba; Argentina
Fil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description In this study, new hydrogels in rod shape were prepared from N-acryloyl-tris-(hydroxymethyl) aminomethane (NAT) using three different crosslinking agents: poly(2-methyl-2-oxazoline) bismacromonomer (BM), ethylene glycol dimethacrylate (EGDMA) and N,N´-methylenebisacrylamide (BIS). Dimethylformamide (DMF) was used as solvent and 2,2´-azobisisobutyronitrile (AIBN) as initiator. Polymeric matrices with different properties were obtained by free radical polymerization by changing the crosslinker (BM, EGDMA or BIS) or the concentration of BM. The hydrogel structures were characterized by high resolution magic angle spinning (HRMAS) NMR technique. Swelling experiments and rheological studies were used to test the water absorption capacity and viscoelastic properties of the hydrogels, respectively. For a given NAT/crosslinking agent molar ratio, the hydrogel synthesized with BM displays higher water absorptive capacity and larger range of linear viscoelasticity than those synthesized with BIS or EGDMA. The relatively larger hydrophilic character of the former and the lower crosslinking density generated by the longer molecules of BM might be the cause of this behavior. The results also reveal that water diffuses into the network following a non-Fickian mechanism. This is concluded from the value of the diffusion exponent n, which is higher than 0.50. The elastic modulus and the equilibrium water content (EWC) measurements suggest that these materials may have potential application as biomaterials.
publishDate 2008
dc.date.none.fl_str_mv 2008-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/25352
Cuggino, Julio César; Alvarez Igarzabal, Cecilia Ines; Rueda, Juan Carlos; Quinzani, Lidia Maria; Komber, Kartmurt; et al.; Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents; Elsevier; European Polymer Journal; 44; 11; 12-2008; 3548-3555
0014-3057
CONICET Digital
CONICET
url http://hdl.handle.net/11336/25352
identifier_str_mv Cuggino, Julio César; Alvarez Igarzabal, Cecilia Ines; Rueda, Juan Carlos; Quinzani, Lidia Maria; Komber, Kartmurt; et al.; Synthesis and Characterization of New Hydrogels Through Copolymerization of N-acryloyl-tris-(hydroxymethyl)aminomethane and Different Crosslinking Agents; Elsevier; European Polymer Journal; 44; 11; 12-2008; 3548-3555
0014-3057
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.eurpolymj.2008.09.010
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0014305708004709
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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