Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)
- Autores
- Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides
- Año de publicación
- 2013
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantify relevant microstructural parameters and electrokinetic properties of this polyampholyte-polypeptide hydrogel, for a well defined range of crosslinker to gelatin mass ratios. These polyampholyte crosslinked matrices having different positive effective electrical charge are studied within an experimental and theoretical framework of their elastic and swelling properties. Estimations of average mesh size and toughness of the swollen hydrogels are provided. The feasibility of polyion complexation between positive crosslinked gelatin chains and negative bioactive macromolecules to be delivered through hydrogel biodegradation is analyzed. Several additional hydrogel properties are estimated like shear modulus, average molecular mass of network strands, swelling ratio, FloryeHuggins interaction parameter, hydrogel electrostatic zeta-potential and average effective charge number per chain before and after the crosslinking process to quantify gelatin chain cationization.
Fil: Porcaro, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentina
Fil: Ottone, Mariel Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentina
Fil: Deiber, Julio Alcides. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentina - Materia
-
Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization
Hydrogel Mechanical Properties
Hydrogel Electrokinetic Properties - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/8870
Ver los metadatos del registro completo
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Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol)Porcaro, AndreaOttone, Mariel LorenaDeiber, Julio AlcidesGelatin-Poly(Vinyl Alcohol) Hydrogel CharacterizationHydrogel Mechanical PropertiesHydrogel Electrokinetic Propertieshttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantify relevant microstructural parameters and electrokinetic properties of this polyampholyte-polypeptide hydrogel, for a well defined range of crosslinker to gelatin mass ratios. These polyampholyte crosslinked matrices having different positive effective electrical charge are studied within an experimental and theoretical framework of their elastic and swelling properties. Estimations of average mesh size and toughness of the swollen hydrogels are provided. The feasibility of polyion complexation between positive crosslinked gelatin chains and negative bioactive macromolecules to be delivered through hydrogel biodegradation is analyzed. Several additional hydrogel properties are estimated like shear modulus, average molecular mass of network strands, swelling ratio, FloryeHuggins interaction parameter, hydrogel electrostatic zeta-potential and average effective charge number per chain before and after the crosslinking process to quantify gelatin chain cationization.Fil: Porcaro, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); ArgentinaFil: Ottone, Mariel Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); ArgentinaFil: Deiber, Julio Alcides. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); ArgentinaElsevier2013-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/8870Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides; Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol); Elsevier; Polymer; 54; 11; 5-2013; 2706-27160032-3861enginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.polymer.2013.03.045info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0032386113002644info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:59:52Zoai:ri.conicet.gov.ar:11336/8870instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:59:52.608CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
title |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
spellingShingle |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) Porcaro, Andrea Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization Hydrogel Mechanical Properties Hydrogel Electrokinetic Properties |
title_short |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
title_full |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
title_fullStr |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
title_full_unstemmed |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
title_sort |
Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol) |
dc.creator.none.fl_str_mv |
Porcaro, Andrea Ottone, Mariel Lorena Deiber, Julio Alcides |
author |
Porcaro, Andrea |
author_facet |
Porcaro, Andrea Ottone, Mariel Lorena Deiber, Julio Alcides |
author_role |
author |
author2 |
Ottone, Mariel Lorena Deiber, Julio Alcides |
author2_role |
author author |
dc.subject.none.fl_str_mv |
Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization Hydrogel Mechanical Properties Hydrogel Electrokinetic Properties |
topic |
Gelatin-Poly(Vinyl Alcohol) Hydrogel Characterization Hydrogel Mechanical Properties Hydrogel Electrokinetic Properties |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.9 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantify relevant microstructural parameters and electrokinetic properties of this polyampholyte-polypeptide hydrogel, for a well defined range of crosslinker to gelatin mass ratios. These polyampholyte crosslinked matrices having different positive effective electrical charge are studied within an experimental and theoretical framework of their elastic and swelling properties. Estimations of average mesh size and toughness of the swollen hydrogels are provided. The feasibility of polyion complexation between positive crosslinked gelatin chains and negative bioactive macromolecules to be delivered through hydrogel biodegradation is analyzed. Several additional hydrogel properties are estimated like shear modulus, average molecular mass of network strands, swelling ratio, FloryeHuggins interaction parameter, hydrogel electrostatic zeta-potential and average effective charge number per chain before and after the crosslinking process to quantify gelatin chain cationization. Fil: Porcaro, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentina Fil: Ottone, Mariel Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentina Fil: Deiber, Julio Alcides. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentina |
description |
The microstructure of polyampholyte gelatin hydrogels crosslinked covalently with fully hydrolyzed poly(vinyl alcohol) is characterized. The experimental methodology involves simple mechanical extension, spectroscopic and thermal methods (FTIR, XRD, DSC, TGA) and equilibrium swelling test to quantify relevant microstructural parameters and electrokinetic properties of this polyampholyte-polypeptide hydrogel, for a well defined range of crosslinker to gelatin mass ratios. These polyampholyte crosslinked matrices having different positive effective electrical charge are studied within an experimental and theoretical framework of their elastic and swelling properties. Estimations of average mesh size and toughness of the swollen hydrogels are provided. The feasibility of polyion complexation between positive crosslinked gelatin chains and negative bioactive macromolecules to be delivered through hydrogel biodegradation is analyzed. Several additional hydrogel properties are estimated like shear modulus, average molecular mass of network strands, swelling ratio, FloryeHuggins interaction parameter, hydrogel electrostatic zeta-potential and average effective charge number per chain before and after the crosslinking process to quantify gelatin chain cationization. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-05 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/8870 Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides; Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol); Elsevier; Polymer; 54; 11; 5-2013; 2706-2716 0032-3861 |
url |
http://hdl.handle.net/11336/8870 |
identifier_str_mv |
Porcaro, Andrea; Ottone, Mariel Lorena; Deiber, Julio Alcides; Microstructure characterization through mechanical, electrokinetic and spectroscopic methods of polyampholyte gelatin hydrogels crosslinked with poly(vinyl alcohol); Elsevier; Polymer; 54; 11; 5-2013; 2706-2716 0032-3861 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.polymer.2013.03.045 info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0032386113002644 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842269607247740928 |
score |
13.13397 |