Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats

Autores
Lado, Maria B.; Burini, Julieta; Rinaldi, Gustavo Juan; Añon, Maria Cristina; Tironi, Valeria Anahi
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The effects of the dietary addition of 2.5 % (w/w) Amaranthus mantegazzianus protein isolate (AI) on blood pressure, lipid profiles and antioxidative status of Wistar rats were evaluated. Six diets were used to feed animals during 28 days: (base (AIN93G), Chol (cholesterol 1 %, w/w), CE (α-tocopherol 0.005 %, w/w), CholE (cholesterol 1 % (w/w) + α-tocopherol 0.005 %, w/w), CAI (AI 2.5 % w/w), CholAI (cholesterol 1 % (w/w) + AI 2.5 %, w/w). Lipid profiles of plasma and liver and faecal cholesterol content were analyzed. Antioxidant status was evaluated by the ferric reducing activity of plasma (FRAP), the 2-thiobarbituric acid (TBA) assay and superoxide dismutase (SOD) activity in plasma and liver. Blood pressure was measured in the tail artery of rats. CholA group presented a significant (α < 0.05) reduction (16 %) in the plasma total cholesterol. In liver, the intake of cholesterol (Chol group) induced a significant increment in cholesterol and triglycerides (2.5 and 2.3 times, respectively), which could be decreased (18 % and 47 %, respectively) by the addition of AI (CholA group). This last group also showed an increased faecal cholesterol excretion (20 %). Increment (50 %) in FRAP values, diminution of TBA value in plasma and liver (70 % and 38 %, respectively) and diminution of SOD activity (20 %) in plasma of CholA group suggest an antioxidant effect because of the intake of AI. In addition, CA and CholA groups presented a diminution (18 %) of blood pressure after 28 days.
Fil: Lado, Maria B.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Fil: Burini, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Fil: Rinaldi, Gustavo Juan. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico La Plata. Centro de Investigaciones Cardiovasculares "Dr. Horacio Eugenio Cingolani"; Argentina
Fil: Añon, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Fil: Tironi, Valeria Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Materia
Amaranth Protein Isolate
Wistar Rats
Antioxidant Status
Hypolipidemic Profile
Hypotensive Effect
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/10596
Acceder
id CONICETDig_d294517d586b7d91ca7f73fd5c0452bf
oai_identifier_str oai:ri.conicet.gov.ar:11336/10596
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of ratsLado, Maria B.Burini, JulietaRinaldi, Gustavo JuanAñon, Maria CristinaTironi, Valeria AnahiAmaranth Protein IsolateWistar RatsAntioxidant StatusHypolipidemic ProfileHypotensive Effecthttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2The effects of the dietary addition of 2.5 % (w/w) Amaranthus mantegazzianus protein isolate (AI) on blood pressure, lipid profiles and antioxidative status of Wistar rats were evaluated. Six diets were used to feed animals during 28 days: (base (AIN93G), Chol (cholesterol 1 %, w/w), CE (α-tocopherol 0.005 %, w/w), CholE (cholesterol 1 % (w/w) + α-tocopherol 0.005 %, w/w), CAI (AI 2.5 % w/w), CholAI (cholesterol 1 % (w/w) + AI 2.5 %, w/w). Lipid profiles of plasma and liver and faecal cholesterol content were analyzed. Antioxidant status was evaluated by the ferric reducing activity of plasma (FRAP), the 2-thiobarbituric acid (TBA) assay and superoxide dismutase (SOD) activity in plasma and liver. Blood pressure was measured in the tail artery of rats. CholA group presented a significant (α < 0.05) reduction (16 %) in the plasma total cholesterol. In liver, the intake of cholesterol (Chol group) induced a significant increment in cholesterol and triglycerides (2.5 and 2.3 times, respectively), which could be decreased (18 % and 47 %, respectively) by the addition of AI (CholA group). This last group also showed an increased faecal cholesterol excretion (20 %). Increment (50 %) in FRAP values, diminution of TBA value in plasma and liver (70 % and 38 %, respectively) and diminution of SOD activity (20 %) in plasma of CholA group suggest an antioxidant effect because of the intake of AI. In addition, CA and CholA groups presented a diminution (18 %) of blood pressure after 28 days.Fil: Lado, Maria B.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; ArgentinaFil: Burini, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; ArgentinaFil: Rinaldi, Gustavo Juan. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico La Plata. Centro de Investigaciones Cardiovasculares "Dr. Horacio Eugenio Cingolani"; ArgentinaFil: Añon, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; ArgentinaFil: Tironi, Valeria Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; ArgentinaSpringer2015-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/10596Lado, Maria B.; Burini, Julieta; Rinaldi, Gustavo Juan; Añon, Maria Cristina; Tironi, Valeria Anahi; Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats; Springer; Plant Foods For Human Nutrition; 70; 4; 12-2015; 371-3790921-96681573-9104enginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s11130-015-0516-3info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007%2Fs11130-015-0516-3info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:31:47Zoai:ri.conicet.gov.ar:11336/10596instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:31:47.987CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
title Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
spellingShingle Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
Lado, Maria B.
Amaranth Protein Isolate
Wistar Rats
Antioxidant Status
Hypolipidemic Profile
Hypotensive Effect
title_short Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
title_full Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
title_fullStr Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
title_full_unstemmed Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
title_sort Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats
dc.creator.none.fl_str_mv Lado, Maria B.
Burini, Julieta
Rinaldi, Gustavo Juan
Añon, Maria Cristina
Tironi, Valeria Anahi
author Lado, Maria B.
author_facet Lado, Maria B.
Burini, Julieta
Rinaldi, Gustavo Juan
Añon, Maria Cristina
Tironi, Valeria Anahi
author_role author
author2 Burini, Julieta
Rinaldi, Gustavo Juan
Añon, Maria Cristina
Tironi, Valeria Anahi
author2_role author
author
author
author
dc.subject.none.fl_str_mv Amaranth Protein Isolate
Wistar Rats
Antioxidant Status
Hypolipidemic Profile
Hypotensive Effect
topic Amaranth Protein Isolate
Wistar Rats
Antioxidant Status
Hypolipidemic Profile
Hypotensive Effect
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv The effects of the dietary addition of 2.5 % (w/w) Amaranthus mantegazzianus protein isolate (AI) on blood pressure, lipid profiles and antioxidative status of Wistar rats were evaluated. Six diets were used to feed animals during 28 days: (base (AIN93G), Chol (cholesterol 1 %, w/w), CE (α-tocopherol 0.005 %, w/w), CholE (cholesterol 1 % (w/w) + α-tocopherol 0.005 %, w/w), CAI (AI 2.5 % w/w), CholAI (cholesterol 1 % (w/w) + AI 2.5 %, w/w). Lipid profiles of plasma and liver and faecal cholesterol content were analyzed. Antioxidant status was evaluated by the ferric reducing activity of plasma (FRAP), the 2-thiobarbituric acid (TBA) assay and superoxide dismutase (SOD) activity in plasma and liver. Blood pressure was measured in the tail artery of rats. CholA group presented a significant (α < 0.05) reduction (16 %) in the plasma total cholesterol. In liver, the intake of cholesterol (Chol group) induced a significant increment in cholesterol and triglycerides (2.5 and 2.3 times, respectively), which could be decreased (18 % and 47 %, respectively) by the addition of AI (CholA group). This last group also showed an increased faecal cholesterol excretion (20 %). Increment (50 %) in FRAP values, diminution of TBA value in plasma and liver (70 % and 38 %, respectively) and diminution of SOD activity (20 %) in plasma of CholA group suggest an antioxidant effect because of the intake of AI. In addition, CA and CholA groups presented a diminution (18 %) of blood pressure after 28 days.
Fil: Lado, Maria B.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Fil: Burini, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Fil: Rinaldi, Gustavo Juan. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnológico La Plata. Centro de Investigaciones Cardiovasculares "Dr. Horacio Eugenio Cingolani"; Argentina
Fil: Añon, Maria Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
Fil: Tironi, Valeria Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Centro de Investigaciones en Criotecnología de Alimentos (i); Argentina. Universidad Nacional de La Plata; Argentina
description The effects of the dietary addition of 2.5 % (w/w) Amaranthus mantegazzianus protein isolate (AI) on blood pressure, lipid profiles and antioxidative status of Wistar rats were evaluated. Six diets were used to feed animals during 28 days: (base (AIN93G), Chol (cholesterol 1 %, w/w), CE (α-tocopherol 0.005 %, w/w), CholE (cholesterol 1 % (w/w) + α-tocopherol 0.005 %, w/w), CAI (AI 2.5 % w/w), CholAI (cholesterol 1 % (w/w) + AI 2.5 %, w/w). Lipid profiles of plasma and liver and faecal cholesterol content were analyzed. Antioxidant status was evaluated by the ferric reducing activity of plasma (FRAP), the 2-thiobarbituric acid (TBA) assay and superoxide dismutase (SOD) activity in plasma and liver. Blood pressure was measured in the tail artery of rats. CholA group presented a significant (α < 0.05) reduction (16 %) in the plasma total cholesterol. In liver, the intake of cholesterol (Chol group) induced a significant increment in cholesterol and triglycerides (2.5 and 2.3 times, respectively), which could be decreased (18 % and 47 %, respectively) by the addition of AI (CholA group). This last group also showed an increased faecal cholesterol excretion (20 %). Increment (50 %) in FRAP values, diminution of TBA value in plasma and liver (70 % and 38 %, respectively) and diminution of SOD activity (20 %) in plasma of CholA group suggest an antioxidant effect because of the intake of AI. In addition, CA and CholA groups presented a diminution (18 %) of blood pressure after 28 days.
publishDate 2015
dc.date.none.fl_str_mv 2015-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/10596
Lado, Maria B.; Burini, Julieta; Rinaldi, Gustavo Juan; Añon, Maria Cristina; Tironi, Valeria Anahi; Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats; Springer; Plant Foods For Human Nutrition; 70; 4; 12-2015; 371-379
0921-9668
1573-9104
url http://hdl.handle.net/11336/10596
identifier_str_mv Lado, Maria B.; Burini, Julieta; Rinaldi, Gustavo Juan; Añon, Maria Cristina; Tironi, Valeria Anahi; Effects of the dietary addition of Amaranth (Amaranthus mantegazzianus) protein isolate on antioxidant status, lipid profiles and blood pressure of rats; Springer; Plant Foods For Human Nutrition; 70; 4; 12-2015; 371-379
0921-9668
1573-9104
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s11130-015-0516-3
info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007%2Fs11130-015-0516-3
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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