Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster

Autores
Gomez, Federico Hernan; Sambucetti, Pablo Daniel; Loeschcke, Volker Helmut Otfried; Norry, Fabian Marcelo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Desiccation, resulting from extremely dry environmental conditions, is a serious obstacle to the survival of organisms. Water is vital for the maintenance of intracellular structure and prevents the irreversible formation of aggregates, an occurrence leading to loss of cellular function. To characterize genetic variation in desiccation stress resistance (DSR) in Drosophila melanogaster Meigen, an intercontinental set of recombinant inbred lines (RIL) is used. Flies are exposed to a low humidity environment (<10% relative humidity) at a constant temperature of 25°C. Desiccation stress resistance is higher in RIL derived from a backcross to the parental stock sensitive to heat stress (from Denmark) than in RIL derived from the reciprocal backcross to the heat-stress resistant stock (from Australia). Composite interval mapping reveals significant quantitative trail loci (QTL) for DSR in the set of RIL. Both major and minor effects QTL are detected, suggesting a complex genetic architecture. When compared with a previous investigation performed on the same set of RIL, the present study indicates that not all traits of resistance to environmental stressors are affected in the same direction by segregating co-localized QTL.
Fil: Gomez, Federico Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Sambucetti, Pablo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Loeschcke, Volker Helmut Otfried. University Aarhus; Dinamarca
Fil: Norry, Fabian Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Materia
DEHYDRATION STRESS
ENVIRONMENTAL STRESS
SMALL INSECTS
THERMAL STRESS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/182483
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogasterGomez, Federico HernanSambucetti, Pablo DanielLoeschcke, Volker Helmut OtfriedNorry, Fabian MarceloDEHYDRATION STRESSENVIRONMENTAL STRESSSMALL INSECTSTHERMAL STRESShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Desiccation, resulting from extremely dry environmental conditions, is a serious obstacle to the survival of organisms. Water is vital for the maintenance of intracellular structure and prevents the irreversible formation of aggregates, an occurrence leading to loss of cellular function. To characterize genetic variation in desiccation stress resistance (DSR) in Drosophila melanogaster Meigen, an intercontinental set of recombinant inbred lines (RIL) is used. Flies are exposed to a low humidity environment (<10% relative humidity) at a constant temperature of 25°C. Desiccation stress resistance is higher in RIL derived from a backcross to the parental stock sensitive to heat stress (from Denmark) than in RIL derived from the reciprocal backcross to the heat-stress resistant stock (from Australia). Composite interval mapping reveals significant quantitative trail loci (QTL) for DSR in the set of RIL. Both major and minor effects QTL are detected, suggesting a complex genetic architecture. When compared with a previous investigation performed on the same set of RIL, the present study indicates that not all traits of resistance to environmental stressors are affected in the same direction by segregating co-localized QTL.Fil: Gomez, Federico Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Sambucetti, Pablo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaFil: Loeschcke, Volker Helmut Otfried. University Aarhus; DinamarcaFil: Norry, Fabian Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; ArgentinaWiley Blackwell Publishing, Inc2015-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/182483Gomez, Federico Hernan; Sambucetti, Pablo Daniel; Loeschcke, Volker Helmut Otfried; Norry, Fabian Marcelo; Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster; Wiley Blackwell Publishing, Inc; Physiological Entomology (print); 40; 3; 7-2015; 205-2110307-6962CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://resjournals.onlinelibrary.wiley.com/doi/full/10.1111/phen.12103info:eu-repo/semantics/altIdentifier/doi/10.1111/phen.12103info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:38:25Zoai:ri.conicet.gov.ar:11336/182483instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:38:26.118CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
title Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
spellingShingle Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
Gomez, Federico Hernan
DEHYDRATION STRESS
ENVIRONMENTAL STRESS
SMALL INSECTS
THERMAL STRESS
title_short Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
title_full Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
title_fullStr Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
title_full_unstemmed Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
title_sort Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster
dc.creator.none.fl_str_mv Gomez, Federico Hernan
Sambucetti, Pablo Daniel
Loeschcke, Volker Helmut Otfried
Norry, Fabian Marcelo
author Gomez, Federico Hernan
author_facet Gomez, Federico Hernan
Sambucetti, Pablo Daniel
Loeschcke, Volker Helmut Otfried
Norry, Fabian Marcelo
author_role author
author2 Sambucetti, Pablo Daniel
Loeschcke, Volker Helmut Otfried
Norry, Fabian Marcelo
author2_role author
author
author
dc.subject.none.fl_str_mv DEHYDRATION STRESS
ENVIRONMENTAL STRESS
SMALL INSECTS
THERMAL STRESS
topic DEHYDRATION STRESS
ENVIRONMENTAL STRESS
SMALL INSECTS
THERMAL STRESS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Desiccation, resulting from extremely dry environmental conditions, is a serious obstacle to the survival of organisms. Water is vital for the maintenance of intracellular structure and prevents the irreversible formation of aggregates, an occurrence leading to loss of cellular function. To characterize genetic variation in desiccation stress resistance (DSR) in Drosophila melanogaster Meigen, an intercontinental set of recombinant inbred lines (RIL) is used. Flies are exposed to a low humidity environment (<10% relative humidity) at a constant temperature of 25°C. Desiccation stress resistance is higher in RIL derived from a backcross to the parental stock sensitive to heat stress (from Denmark) than in RIL derived from the reciprocal backcross to the heat-stress resistant stock (from Australia). Composite interval mapping reveals significant quantitative trail loci (QTL) for DSR in the set of RIL. Both major and minor effects QTL are detected, suggesting a complex genetic architecture. When compared with a previous investigation performed on the same set of RIL, the present study indicates that not all traits of resistance to environmental stressors are affected in the same direction by segregating co-localized QTL.
Fil: Gomez, Federico Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Sambucetti, Pablo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
Fil: Loeschcke, Volker Helmut Otfried. University Aarhus; Dinamarca
Fil: Norry, Fabian Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Ecología, Genética y Evolución de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Ecología, Genética y Evolución de Buenos Aires; Argentina
description Desiccation, resulting from extremely dry environmental conditions, is a serious obstacle to the survival of organisms. Water is vital for the maintenance of intracellular structure and prevents the irreversible formation of aggregates, an occurrence leading to loss of cellular function. To characterize genetic variation in desiccation stress resistance (DSR) in Drosophila melanogaster Meigen, an intercontinental set of recombinant inbred lines (RIL) is used. Flies are exposed to a low humidity environment (<10% relative humidity) at a constant temperature of 25°C. Desiccation stress resistance is higher in RIL derived from a backcross to the parental stock sensitive to heat stress (from Denmark) than in RIL derived from the reciprocal backcross to the heat-stress resistant stock (from Australia). Composite interval mapping reveals significant quantitative trail loci (QTL) for DSR in the set of RIL. Both major and minor effects QTL are detected, suggesting a complex genetic architecture. When compared with a previous investigation performed on the same set of RIL, the present study indicates that not all traits of resistance to environmental stressors are affected in the same direction by segregating co-localized QTL.
publishDate 2015
dc.date.none.fl_str_mv 2015-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/182483
Gomez, Federico Hernan; Sambucetti, Pablo Daniel; Loeschcke, Volker Helmut Otfried; Norry, Fabian Marcelo; Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster; Wiley Blackwell Publishing, Inc; Physiological Entomology (print); 40; 3; 7-2015; 205-211
0307-6962
CONICET Digital
CONICET
url http://hdl.handle.net/11336/182483
identifier_str_mv Gomez, Federico Hernan; Sambucetti, Pablo Daniel; Loeschcke, Volker Helmut Otfried; Norry, Fabian Marcelo; Patterns of variation in desiccation resistance in a set of recombinant inbred lines in Drosophila melanogaster; Wiley Blackwell Publishing, Inc; Physiological Entomology (print); 40; 3; 7-2015; 205-211
0307-6962
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://resjournals.onlinelibrary.wiley.com/doi/full/10.1111/phen.12103
info:eu-repo/semantics/altIdentifier/doi/10.1111/phen.12103
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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