Nanoberries for topical delivery of antioxidants
- Autores
- Martinetti Montanari, Jorge Anibal; Vera, Maria; Mensi, Emanuel; Morilla, María José; Romero, Eder Lilia
- Año de publicación
- 2013
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- With the aim of improving the antioxidant activity of polyphenols from blueberries (Vaccinium myrtillus) on skin targets after topical application, ethanolic extracts from three blueberry varieties (named Millenia, O?Neal and Blue Crisp) were loaded into ultradeformable liposomes. These nanocarriers are known to be capable of penetrating through the stratum corneum reaching its deeper layers and the viable epidermis. On the other hand, blueberries contain large amounts of polyphenols, whose antioxidant properties as tissue protectors against processes mediated by reactive oxygen species have been extensively proved. Blueberries are usually consumed as edible products, but their antioxidant compounds are poorly absorbed. The antioxidant properties of the extracts were screened before and after being loaded into ultradeformable liposomes made of soy phosphatidylcholine and sodium cholate, of nearly 100 nm in size at 0.223 extract/lipid w/w. The ethanolic extract-loaded ultradeformable liposomes (nano-berries) from Millenia variety retained an 85 % of the antioxidant capacity of the free extract and showed low cytotoxicity on HaCaT cells (less than 20%) at active concentration against free radicals.
Fil: Martinetti Montanari, Jorge Anibal. Universidad Nacional de Quilmes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Vera, Maria. Universidad Nacional de Quilmes; Argentina
Fil: Mensi, Emanuel. Universidad Nacional de Quilmes; Argentina
Fil: Morilla, María José. Universidad Nacional de Quilmes; Argentina
Fil: Romero, Eder Lilia. Universidad Nacional de Quilmes; Argentina - Materia
-
Blueberry
Nanocosmetics
Ultradeformable
Liposomes
Antioxidants - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/24741
Ver los metadatos del registro completo
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Nanoberries for topical delivery of antioxidantsMartinetti Montanari, Jorge AnibalVera, MariaMensi, EmanuelMorilla, María JoséRomero, Eder LiliaBlueberryNanocosmeticsUltradeformableLiposomesAntioxidantshttps://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2With the aim of improving the antioxidant activity of polyphenols from blueberries (Vaccinium myrtillus) on skin targets after topical application, ethanolic extracts from three blueberry varieties (named Millenia, O?Neal and Blue Crisp) were loaded into ultradeformable liposomes. These nanocarriers are known to be capable of penetrating through the stratum corneum reaching its deeper layers and the viable epidermis. On the other hand, blueberries contain large amounts of polyphenols, whose antioxidant properties as tissue protectors against processes mediated by reactive oxygen species have been extensively proved. Blueberries are usually consumed as edible products, but their antioxidant compounds are poorly absorbed. The antioxidant properties of the extracts were screened before and after being loaded into ultradeformable liposomes made of soy phosphatidylcholine and sodium cholate, of nearly 100 nm in size at 0.223 extract/lipid w/w. The ethanolic extract-loaded ultradeformable liposomes (nano-berries) from Millenia variety retained an 85 % of the antioxidant capacity of the free extract and showed low cytotoxicity on HaCaT cells (less than 20%) at active concentration against free radicals.Fil: Martinetti Montanari, Jorge Anibal. Universidad Nacional de Quilmes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vera, Maria. Universidad Nacional de Quilmes; ArgentinaFil: Mensi, Emanuel. Universidad Nacional de Quilmes; ArgentinaFil: Morilla, María José. Universidad Nacional de Quilmes; ArgentinaFil: Romero, Eder Lilia. Universidad Nacional de Quilmes; ArgentinaSociety of Cosmetic Chemists2013-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/zipapplication/pdfhttp://hdl.handle.net/11336/24741Martinetti Montanari, Jorge Anibal; Vera, Maria; Mensi, Emanuel; Morilla, María José; Romero, Eder Lilia; Nanoberries for topical delivery of antioxidants; Society of Cosmetic Chemists; Journal of Cosmetic Science; 64; 6; 11-2013; 469-4821525-7886CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://journal.scconline.org/abstracts/cc2013/cc064n06/p00469-p00482.htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:05:22Zoai:ri.conicet.gov.ar:11336/24741instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:05:23.241CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Nanoberries for topical delivery of antioxidants |
title |
Nanoberries for topical delivery of antioxidants |
spellingShingle |
Nanoberries for topical delivery of antioxidants Martinetti Montanari, Jorge Anibal Blueberry Nanocosmetics Ultradeformable Liposomes Antioxidants |
title_short |
Nanoberries for topical delivery of antioxidants |
title_full |
Nanoberries for topical delivery of antioxidants |
title_fullStr |
Nanoberries for topical delivery of antioxidants |
title_full_unstemmed |
Nanoberries for topical delivery of antioxidants |
title_sort |
Nanoberries for topical delivery of antioxidants |
dc.creator.none.fl_str_mv |
Martinetti Montanari, Jorge Anibal Vera, Maria Mensi, Emanuel Morilla, María José Romero, Eder Lilia |
author |
Martinetti Montanari, Jorge Anibal |
author_facet |
Martinetti Montanari, Jorge Anibal Vera, Maria Mensi, Emanuel Morilla, María José Romero, Eder Lilia |
author_role |
author |
author2 |
Vera, Maria Mensi, Emanuel Morilla, María José Romero, Eder Lilia |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
Blueberry Nanocosmetics Ultradeformable Liposomes Antioxidants |
topic |
Blueberry Nanocosmetics Ultradeformable Liposomes Antioxidants |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.10 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
With the aim of improving the antioxidant activity of polyphenols from blueberries (Vaccinium myrtillus) on skin targets after topical application, ethanolic extracts from three blueberry varieties (named Millenia, O?Neal and Blue Crisp) were loaded into ultradeformable liposomes. These nanocarriers are known to be capable of penetrating through the stratum corneum reaching its deeper layers and the viable epidermis. On the other hand, blueberries contain large amounts of polyphenols, whose antioxidant properties as tissue protectors against processes mediated by reactive oxygen species have been extensively proved. Blueberries are usually consumed as edible products, but their antioxidant compounds are poorly absorbed. The antioxidant properties of the extracts were screened before and after being loaded into ultradeformable liposomes made of soy phosphatidylcholine and sodium cholate, of nearly 100 nm in size at 0.223 extract/lipid w/w. The ethanolic extract-loaded ultradeformable liposomes (nano-berries) from Millenia variety retained an 85 % of the antioxidant capacity of the free extract and showed low cytotoxicity on HaCaT cells (less than 20%) at active concentration against free radicals. Fil: Martinetti Montanari, Jorge Anibal. Universidad Nacional de Quilmes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Vera, Maria. Universidad Nacional de Quilmes; Argentina Fil: Mensi, Emanuel. Universidad Nacional de Quilmes; Argentina Fil: Morilla, María José. Universidad Nacional de Quilmes; Argentina Fil: Romero, Eder Lilia. Universidad Nacional de Quilmes; Argentina |
description |
With the aim of improving the antioxidant activity of polyphenols from blueberries (Vaccinium myrtillus) on skin targets after topical application, ethanolic extracts from three blueberry varieties (named Millenia, O?Neal and Blue Crisp) were loaded into ultradeformable liposomes. These nanocarriers are known to be capable of penetrating through the stratum corneum reaching its deeper layers and the viable epidermis. On the other hand, blueberries contain large amounts of polyphenols, whose antioxidant properties as tissue protectors against processes mediated by reactive oxygen species have been extensively proved. Blueberries are usually consumed as edible products, but their antioxidant compounds are poorly absorbed. The antioxidant properties of the extracts were screened before and after being loaded into ultradeformable liposomes made of soy phosphatidylcholine and sodium cholate, of nearly 100 nm in size at 0.223 extract/lipid w/w. The ethanolic extract-loaded ultradeformable liposomes (nano-berries) from Millenia variety retained an 85 % of the antioxidant capacity of the free extract and showed low cytotoxicity on HaCaT cells (less than 20%) at active concentration against free radicals. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-11 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/24741 Martinetti Montanari, Jorge Anibal; Vera, Maria; Mensi, Emanuel; Morilla, María José; Romero, Eder Lilia; Nanoberries for topical delivery of antioxidants; Society of Cosmetic Chemists; Journal of Cosmetic Science; 64; 6; 11-2013; 469-482 1525-7886 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/24741 |
identifier_str_mv |
Martinetti Montanari, Jorge Anibal; Vera, Maria; Mensi, Emanuel; Morilla, María José; Romero, Eder Lilia; Nanoberries for topical delivery of antioxidants; Society of Cosmetic Chemists; Journal of Cosmetic Science; 64; 6; 11-2013; 469-482 1525-7886 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://journal.scconline.org/abstracts/cc2013/cc064n06/p00469-p00482.html |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/zip application/pdf |
dc.publisher.none.fl_str_mv |
Society of Cosmetic Chemists |
publisher.none.fl_str_mv |
Society of Cosmetic Chemists |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1842269909306834944 |
score |
13.13397 |